公开(公告)号：US20250065149A1

公开(公告)日：2025-02-27

申请号：US18729485

申请日：2023-01-17

Applicant: QUIREM Medical B.V.

Inventor： Gradus VAN WOLFSWINKEL

IPC: A61N5/10 ,  A61M5/178 ,  A61M5/20

Abstract: A system (1) for administration of a mixture of particles, the system comprising an administration subsystem (3) comprising at least one administration hydraulic element (14) for containing a mixture with the particles, wherein the at least one administration hydraulic element is movably mounted for, when moving, homogenizing the mixture, wherein said at least one administration hydraulic element is arranged for administering of the mixture to a further system (15), an actuation subsystem (2) comprising at least one actuation hydraulic element (4); wherein the at least one actuation hydraulic element is operably connected to the at least one administration hydraulic element for actuating said administration hydraulic element to administer mixture to the further system; wherein the at least one actuation hydraulic element is further fluidly connected with an operating element (5) to operate the at least one actuation hydraulic element.

公开(公告)号：US20250065047A1

公开(公告)日：2025-02-27

申请号：US18830332

申请日：2024-09-10

Applicant: Masaki MATSUMOTO

Inventor： Masaki MATSUMOTO

IPC: A61M5/178 ,  A61J15/00

Abstract: [Problem] To provide an economic suction adaptor that is capable of suctioning a highly viscous enteral nutrient to a gastric fistula catheter syringe without the intake of air.
[Solution] The number of people having meals of highly viscous enteral nutrients such as blended diets through a gastric fistula catheter is increasing among pediatric patients who need long-term intubation nutrients, and among elderly people who have trouble with oral intake. Suctioning a blended diet on a dish with a syringe alone is undesirable because air is introduced. The suction adaptor of the present invention is used by being connected to the syringe, wherein a suction tube having, on an upper portion thereof, a connection part connected to a nozzle of the syringe is formed in the middle of a bowl-shaped suction pad which is an elastic body.

公开(公告)号：US20250064634A1

公开(公告)日：2025-02-27

申请号：US18652633

申请日：2024-05-01

Applicant: ForSight Vision4, Inc.

Inventor： Eugene de Juan, JR. ,  Yair Alster ,  Kathleen Cogan Farinas ,  K. Angela Macfarlane ,  Cary J. Reich ,  Randolph E. Campbell ,  Darren Doud ,  Signe Erickson ,  Michael Barrett ,  David Batten ,  Christina Skieller ,  Greg Stine

IPC: A61F9/00 ,  A61M5/142 ,  A61M5/178 ,  A61M5/31 ,  A61M5/32 ,  A61M5/46 ,  A61M39/02

Abstract: Methods and apparatus provide a therapeutic fluid to devices implanted in the body, for example to containers of devices implanted in the eye of a patient. The methods and apparatus may comprise an injector to increase an amount of therapeutic agent injected into the device implanted in the eye, or a structure to receive the therapeutic fluid within the device implanted in the eye, or combinations thereof. The device implanted in the eye may comprise a reservoir chamber having a fluid with a density different than the therapeutic fluid, and the apparatus can be adapted to at least partially separate the implanted device fluid from therapeutic fluid within the reservoir chamber to increase and amount of therapeutic fluid placed in the reservoir chamber.

公开(公告)号：US12226607B2

公开(公告)日：2025-02-18

申请号：US18819145

申请日：2024-08-29

Applicant: Jubilant Draximage Inc.

Inventor： James A. Kaufman ,  Dominic Siewko ,  Indranil Nandi

IPC: A61M5/142 ,  A61M5/168 ,  A61M5/178 ,  G16H10/60 ,  G16H40/63

Abstract: The invention is a theranostic delivery system or radiopharmaceutical drugs delivery system with movable workstation having handles. The workstation of theranostic delivery system or radiopharmaceutical drugs delivery system also has an on-board shielded disposal system for waste collection, which is operated by foot actuated system for locked and unlocked modes during the device journey. The theranostic delivery system or radiopharmaceutical drugs delivery system comprises a status light system that illuminates the working area to enable distance monitoring. Further, the delivery system includes a disposable secondary containment system that protects the core workstation from contamination, a configurable dose transporter and a disposable sealed fluid cartridge to withdraw custom volume from the vial or syringe. The delivery system includes a theranostic informatics management system, which contains a computer screen as a graphical user interface with a retractable rotating arm to receive the various patient infusion parameters.

公开(公告)号：US20250042972A1

公开(公告)日：2025-02-06

申请号：US18924707

申请日：2024-10-23

Applicant: Regeneron Pharmaceuticals, Inc.

Inventor： Eric FURFINE ,  Daniel DIX ,  Kenneth GRAHAM ,  Kelly FRYE

IPC: C07K14/71 ,  A61K9/00 ,  A61K9/19 ,  A61K38/17 ,  A61K47/02 ,  A61K47/10 ,  A61K47/26 ,  A61M5/178 ,  C07K14/47

Abstract: Ophthalmic formulations of a vascular endothelial growth factor (VEGF)-specific fusion protein antagonist are provided suitable for intravitreal administration to the eye. The ophthalmic formulations include a stable liquid formulation and a lyophilizable formulation. Preferably, the protein antagonist has an amino acid sequence of SEQ ID NO:4.

公开(公告)号：US20250041521A1

公开(公告)日：2025-02-06

申请号：US18927335

申请日：2024-10-25

Applicant: HALOZYME, INC.

Inventor： Paul R. Lesch

IPC: A61M5/20 ,  A61M5/178 ,  A61M5/28 ,  A61M5/30 ,  A61M5/32 ,  A61M5/46 ,  A61M5/48

Abstract: A jet injector that includes a prefilled syringe. The syringe includes a fluid chamber that contains a medicament. The syringe also has an injection-assisting needle, and a plunger is movable within the fluid chamber. A housing is configured for allowing insertion of the needle to a penetration depth. An energy source is configured for biasing the plunger to produce an injecting pressure in the medicament in the fluid chamber of between about 80 and 1000 p.s.i. to jet inject the medicament from the fluid chamber through the needle to an injection site.

公开(公告)号：US20250032715A1

公开(公告)日：2025-01-30

申请号：US18915974

申请日：2024-10-15

Applicant: DexCom, Inc.

Inventor： John Michael Dobbles ,  Apurv Ullas Kamath ,  Aarthi Mahalingam ,  James H. Brauker

IPC: A61M5/172 ,  A61B5/00 ,  A61B5/145 ,  A61M5/00 ,  A61M5/142 ,  A61M5/178 ,  A61M5/20 ,  A61M5/30 ,  A61M11/00 ,  A61M15/00 ,  A61M35/00 ,  G16H20/17 ,  G16H40/63

Abstract: Systems and methods for integrating a continuous glucose sensor 12, including a receiver 14, a medicament delivery device 16, a controller module, and optionally a single point glucose monitor 18 are provided. Integration may be manual, semi-automated and/or fully automated.

公开(公告)号：US20250032714A1

公开(公告)日：2025-01-30

申请号：US18915878

申请日：2024-10-15

Applicant: DexCom, Inc.

Inventor： John Michael Dobbles ,  Apurv Ullas Kamath ,  Aarthi Mahalingam ,  James H. Brauker

IPC: A61M5/172 ,  A61B5/00 ,  A61B5/145 ,  A61M5/00 ,  A61M5/142 ,  A61M5/178 ,  A61M5/20 ,  A61M5/30 ,  A61M11/00 ,  A61M15/00 ,  A61M35/00 ,  G16H20/17 ,  G16H40/63

Abstract: Systems and methods for integrating a continuous glucose sensor 12, including a receiver 14, a medicament delivery device 16, a controller module, and optionally a single point glucose monitor 18 are provided. Integration may be manual, semi-automated and/or fully automated.

公开(公告)号：US12194284B2

公开(公告)日：2025-01-14

申请号：US16615991

申请日：2018-05-25

Applicant: West Pharmaceutical Services, Inc.

Inventor： Stacy Faught ,  Jorge Santos

IPC: A61M5/20 ,  A61M5/24 ,  A61M5/315 ,  A61M5/178 ,  G16H20/17 ,  G16H40/63

Abstract: A syringe includes a plunger having multiple sections of differing diameters or materials, and a barrel with a cavity into which the plunger is inserted. The barrel includes a first probe and a second probe opposite to one another such that an interior volume of the barrel is radially between the first and second probes. A microcontroller is configured to measure a capacitance between the first and second probes, with the measured capacitance having a first capacitance value when the first section of the plunger shaft is between the first and second probes and a second capacitance value different from the first capacitance value when a second section of the plunger shaft is between the first and second probes. The microcontroller is configured to determine that an injection has been completed when the second capacitance value is measured.

公开(公告)号：US12194141B2

公开(公告)日：2025-01-14

申请号：US17142744

申请日：2021-01-06

Applicant: Nevakar Injectables Inc.

Inventor： Kumaresh Soppimath ,  Tushar Hingorani ,  Anant Patel

IPC: A61K9/00 ,  A61K31/137 ,  A61K31/225 ,  A61K47/02 ,  A61K47/12 ,  A61M5/145 ,  A61M5/178 ,  A61M5/31 ,  A61M25/00 ,  A61M39/10

Abstract: Pre-filled syringes, pharmaceutical compositions, and kits and methods relating to same allow for emergency administration of one or more drugs from prefilled glass syringes to a patient via a needleless connector. In preferred embodiments, the prefilled glass syringe has a drug volume of at least 5 mL, has a Luer-lock, and has a syringe tip with an internal channel that has a diameter of about 1.7 mm. Such syringes advantageously allow storage of emergency drugs without leaching of plastic materials and degradation, and substantially improve the safety profile where the syringe is attached to an IV line via a needleless connector.