公开(公告)号：US20240342374A1

公开(公告)日：2024-10-17

申请号：US18682140

申请日：2022-08-12

申请人： Becton, Dickinson and Copany

发明人： Tianqi Hang ,  Nicole Jean DiStefano ,  Balaji Sadasivam ,  Rafael Gonzalez Macias ,  Noel Antonio Medrano ,  Shivani Rajesh Patel

IPC分类号： A61M5/178 ,  A61M5/34 ,  A61M39/10

CPC分类号： A61M5/1782 ,  A61M5/343 ,  A61M2039/1066

摘要： A syringe adapter includes an outer housing having a sidewall defining an interior space, a membrane housing positioned within the interior space of the outer housing and moveable from a first position within the outer housing to a second position within the outer housing spaced from the first position, with the membrane housing receiving a membrane, a needle hub connected to the outer housing and configured to be connected to a syringe, with the needle hub rotatable relative to the outer housing, and a needle connected to the needle hub. The needle having a first end and a second end positioned opposite the first end, with the second end of the needle received within the membrane when membrane housing is in the first position. The needle is rotatable relative to the needle hub.

公开(公告)号：US12109396B2

公开(公告)日：2024-10-08

申请号：US17845392

申请日：2022-06-21

申请人： CareFusion 303, Inc.

发明人： George Mansour ,  Eugene Mason ,  Ryan Callahan ,  Todd Oda ,  Wesley Underwood ,  Adel Shams ,  Dylan Beyhl ,  Seyed Salehi Borojerdi

IPC分类号： A61M5/19 ,  A61M5/28 ,  A61M5/178 ,  A61M5/31

CPC分类号： A61M5/19 ,  A61M5/284 ,  A61M2005/1787 ,  A61M2005/3132

摘要： A dual-chamber syringe may include an end wall and a primary plunger. The primary plunger may include a primary stopper. The primary stopper may form a primary chamber with the end wall. A secondary plunger may be in mechanical association with the primary plunger. The secondary plunger may include a secondary stopper. The secondary stopper may form a secondary chamber with the primary stopper. A primary nozzle may extend from the end wall and may be in fluid communication with the primary chamber. A secondary nozzle may extend from the end wall and may be in fluid communication with the secondary chamber.

公开(公告)号：US12102789B1

公开(公告)日：2024-10-01

申请号：US18618798

申请日：2024-03-27

申请人： Jubilant Draximage Inc.

发明人： James A. Kaufman ,  Dominic Siewko ,  Indranil Nandi

IPC分类号： A61M5/142 ,  A61M5/168 ,  A61M5/178 ,  G16H10/60 ,  G16H40/63

CPC分类号： A61M5/142 ,  A61M5/16831 ,  A61M5/1785 ,  G16H10/60 ,  G16H40/63 ,  A61M2005/14208 ,  A61M2005/16863 ,  A61M2202/0007 ,  A61M2202/049 ,  A61M2205/10 ,  A61M2205/18 ,  A61M2205/3327 ,  A61M2205/3331 ,  A61M2205/3379 ,  A61M2205/502 ,  A61M2205/584 ,  A61M2205/6009

摘要： The invention is a theranostic delivery system or radiopharmaceutical drugs delivery system with movable workstation having handles. The workstation of theranostic delivery system or radiopharmaceutical drugs delivery system also has an on-board shielded disposal system for waste collection, which is operated by foot actuated system for locked and unlocked modes during the device journey. The theranostic delivery system or radiopharmaceutical drugs delivery system comprises a status light system that illuminates the working area to enable distance monitoring. Further, the delivery system includes a disposable secondary containment system that protects the core workstation from contamination, a configurable dose transporter and a disposable sealed fluid cartridge to withdraw custom volume from the vial or syringe. The delivery system includes a theranostic informatics management system, which contains a computer screen as a graphical user interface with a retractable rotating arm to receive the various patient infusion parameters.

公开(公告)号：US20240299532A1

公开(公告)日：2024-09-12

申请号：US18549722

申请日：2022-03-09

申请人： The Board of Trustees of the Leland Stanford Junior University

发明人： Eric Andrew Appel ,  Emily C. Gale ,  Lingyin Li ,  Lauren J. Lahey

IPC分类号： A61K39/215 ,  A61K39/00 ,  A61M5/178 ,  A61P37/04

CPC分类号： A61K39/215 ,  A61M5/178 ,  A61P37/04 ,  A61K2039/54 ,  A61K2039/55505 ,  A61K2039/55511 ,  A61K2039/5555 ,  A61K2039/55561 ,  A61K2039/55572 ,  A61K2039/55577 ,  A61K2039/6087 ,  A61K2039/6093

摘要： Provided herein are vaccine delivery systems including a polymer hydrogel non-covalently crossed-linked with a plurality of nanoparticles, a dinucleotide adjuvant encapsulated in the hydrogel, and an antigen encapsulated in the hydrogel. The provided vaccine delivery systems are particularly useful for slowly releasing the antigen and adjuvant within a subject, thereby triggering a more therapeutically effective immune response. Also provided are kits including the disclosed vaccine delivery systems, and methods of using the disclosed materials.

公开(公告)号：US20240280395A1

公开(公告)日：2024-08-22

申请号：US18642437

申请日：2024-04-22

申请人： Becton, Dickinson and Company

发明人： Gary SEARLE ,  Francis L. ROSS, III

IPC分类号： G01F11/02 ,  A61M5/142 ,  A61M5/168 ,  A61M5/172 ,  A61M5/178 ,  A61M5/31 ,  A61M5/315 ,  B65B3/00 ,  G01R33/07 ,  G16H20/17

CPC分类号： G01F11/027 ,  A61M5/14248 ,  A61M5/16804 ,  A61M5/16831 ,  A61M5/172 ,  A61M5/31511 ,  G01R33/072 ,  A61M5/1782 ,  A61M2005/3125 ,  A61M2205/3317 ,  A61M2205/3389 ,  A61M2205/3576 ,  A61M2205/50 ,  B65B3/003 ,  G16H20/17

摘要： A system for capture of dose delivery information is provided. The system includes a medication delivery device, a dose information capture device adapted to be attached to the medication delivery device, and a target element adapted to be attached to the medication delivery device. The target element comprises a magnet or ferrous element and the target element attaches to the medication delivery device on a dose delivery mechanism of the medication delivery device. The dose information capture device includes a magnetic position sensor adapted to detect a position of the target element. As an alternative to magnetic sensing, MEMS flow sensors, and the like may also be used. Exemplary systems preferably transmit dose information in real time to remote devices for further processing.

公开(公告)号：US20240277936A1

公开(公告)日：2024-08-22

申请号：US18693303

申请日：2022-09-14

申请人： SHL Medical AG

发明人： Anders Boström

IPC分类号： A61M5/178

CPC分类号： A61M5/178 ,  A61M2205/581 ,  A61M2205/582

摘要： The present disclosure provides a feedback mechanism for a medicament delivery device, comprising: a rotator, and a ring member arranged coaxially with the rotator, wherein the rotator and the ring member are configured to be rotatable relative to each other, wherein one of the rotator and the ring member has a radially resilient feedback structure and the other one of the rotator and the ring member has a first counter feedback structure configured to interact with the feedback structure when one of the rotator and the ring member is rotated relative to the other one of the rotator and the ring member, wherein when the feedback structure interacts with the first counter feedback structure the feedback structure is configured to relax and hit the first counter feedback structure to thereby provide a first feedback sound.

公开(公告)号：US20240261189A1

公开(公告)日：2024-08-08

申请号：US18612266

申请日：2024-03-21

申请人： BAYER HEALTHCARE LLC

发明人： Michael Swantner ,  Ian Menego

IPC分类号： A61J1/20 ,  A61M5/178 ,  A61M39/10

CPC分类号： A61J1/2096 ,  A61M5/1782 ,  A61M39/1011

摘要： A fluid path connector for a medical fluid delivery system, the fluid path connector including a first connector element comprising a body, a first lumen, a first flexible leg, and a second flexible leg, and a second connector element comprising a body defining an undercut, a second lumen, a channel defined in the body, and at least one sealing element positioned within the channel, in which the first flexible leg comprises a first flange and the second flexible leg comprises a second flange, and in which, upon engagement of the first connector element with the second connector element, the first flange and the second flange engage with the undercut of the body of the second connector element to prevent disengagement of the first connector element and the second connector element.

公开(公告)号：US12053618B2

公开(公告)日：2024-08-06

申请号：US16761149

申请日：2018-11-06

申请人： AMGEN INC.

发明人： Justin Harris ,  Matthew Wayne Janke ,  Wael Mismar ,  Jerome Olivas ,  Thomas Clark Pearson ,  Sudeshna Dutta Ray ,  Ryan M. Agard ,  Alexis Dechelette ,  Michael Gammelager ,  Mads Hansen ,  Valerio Mazzon ,  Owen Ryan ,  Clive Smith

IPC分类号： A61M5/28 ,  A61M5/178 ,  A61M5/24 ,  A61M5/31

CPC分类号： A61M5/28 ,  A61M5/1782 ,  A61M5/24 ,  A61M5/3134 ,  A61M2005/2488 ,  A61M2005/3115

摘要： Fill-finish assemblies facilitating the manufacture of a drug delivery device are disclosed. The fill-finish assembly may include a container, an insertion mechanism, a fluid pathway connection assembly disposed between the container and the insertion mechanism, and a carrier. The insertion mechanism may include a delivery member and an insertion mechanism housing. The insertion mechanism may be configured to move the delivery member from a retracted position inside the insertion mechanism housing to a deployed position outside the insertion mechanism housing. The fluid pathway connection assembly may be selectively activatable to establish fluid communication between the container and the delivery member. The carrier may have a hollow interior containing at least a portion of each of the container, the insertion mechanism, and the fluid pathway connection assembly. The carrier may be configured to hold the container, the insertion mechanism, and the fluid pathway connection assembly in alignment with each other.

公开(公告)号：US12053610B2

公开(公告)日：2024-08-06

申请号：US15672691

申请日：2017-08-09

申请人： Kimberley Levy ,  Frank Levy

发明人： Kimberley Levy ,  Frank Levy

IPC分类号： A61M39/22 ,  A61M5/00 ,  A61M5/19 ,  A61M5/178 ,  A61M39/00 ,  A61M39/24

CPC分类号： A61M5/007 ,  A61M5/19 ,  A61M39/223 ,  A61M2005/006 ,  A61M2005/1787 ,  A61M2039/0009 ,  A61M2039/0027 ,  A61M39/24 ,  A61M2202/0225 ,  F04C2270/0421

摘要： A system for controlled delivery of medical fluids to a patient includes an inlet conduit attached to a source of a medical fluid and an outlet conduit connected to the patient. The inlet and outlet conduits are interconnected by a multiple stage control valve assembly and a pair of syringes. The control valve assembly is alternated between a first state wherein the inlet conduit communicates with a first syringe for transmitting fluid from the source to the first syringe, a second state wherein the first syringe communicates with a second syringe and is isolated from the inlet conduit and the outlet for transmitting fluid from the first syringe to the second syringe, and a third state wherein the second syringe communicates with the outlet and is isolated from the inlet and the first syringe for transmitting fluid from the second syringe to the patient through the outlet.

公开(公告)号：US12042633B2

公开(公告)日：2024-07-23

申请号：US17622410

申请日：2020-06-23

申请人： Revive Innovations +Ltd

发明人： Abhisheik Kamal ,  Urshita Gautam ,  Alexander Kalogroulis

IPC分类号： A61M5/19 ,  A61M5/178 ,  A61M5/20 ,  A61M5/28 ,  A61M5/34

CPC分类号： A61M5/19 ,  A61M5/178 ,  A61M5/20 ,  A61M2005/206 ,  A61M5/281 ,  A61M2005/342

摘要： A syringe (200, 400) for use in a medication delivery device (100) comprises a vial. The vial (201, 411) comprises a chamber (206). The chamber is configured to receive a piston or plunger (205, 416). The syringe further comprises a needle attachment point (202), for the attachment of a hypodermic needle (204). The chamber is offset from the needle attachment point.