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1.发明授权公开(公告)号：US12128221B2
公开(公告)日：2024-10-29
申请号：US17336263
申请日：2021-06-01
CPC分类号： A61M5/31596 , A61M5/19 , A61M5/2066 , A61M5/3202 , A61M5/3294 , A61M2005/202 , A61M2005/2073 , A61M2005/31598
摘要： A mixing device configured to hold two containers, each having a separate medicament component disposed therein. A fluidic channel is provided that upon creating fluidic communication with each container once seals about each container are opened. Then a transfer mechanism can transfer the medicament components from one container to the other container until ready to be delivered or transferred through the fluidic channel through a delivery assembly.
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公开(公告)号：US12128209B2
公开(公告)日：2024-10-29
申请号：US18347076
申请日：2023-07-05
申请人： Sanofi
发明人： Michael Helmer
IPC分类号： A61M5/00 , A61M5/20 , F25D11/00 , G06K7/10 , G06K7/14 , G06Q10/0875 , G16H20/17 , G16H40/20 , G16H40/40 , G16H40/67 , H04W76/10
CPC分类号： A61M5/002 , A61M5/20 , F25D11/00 , G06K7/10297 , G06K7/10861 , G06K7/1413 , G06Q10/0875 , G16H20/17 , G16H40/20 , G16H40/40 , G16H40/67 , H04W76/10 , A61M2205/3576 , A61M2205/3606 , A61M2205/502 , A61M2205/52 , A61M2205/6054 , A61M2205/6063 , A61M2205/6072 , G06K2007/10504
摘要： A computing device comprises a memory and a data interface for connecting to a corresponding interface in a storage assembly. The memory comprises instructions which, on connection with the storage assembly, cause a processor of the storage assembly to: detect, using a device sensor of the storage assembly, one or more medicament delivery devices stored in the storage assembly; and display, on a display screen provided on the storage assembly, information relating to a medicament stored in the storage assembly.
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公开(公告)号：US12121704B2
公开(公告)日：2024-10-22
申请号：US17930950
申请日：2022-09-09
申请人： Antares Pharma, Inc.
发明人： Paul R. Lesch , Matthew H. Rust , Thomas E. Kramer
CPC分类号： A61M5/2033 , A61M2005/2013 , A61M2005/206 , A61M5/30 , A61M2005/3125 , A61M5/31541 , A61M5/31553 , A61M5/31563 , A61M5/3158 , A61M5/31591 , A61M5/3202 , A61M5/326 , A61M5/425
摘要： An injector for injecting a medicament in a patient. The injector includes a container comprising a fluid chamber containing a first volume of a medicament, and an injection conduit associated with the fluid chamber for defining a fluid pathway therefrom to inject the medicament from the fluid chamber through the injection conduit to an injection location. The injector also includes a firing mechanism associated with the fluid chamber for expelling the medicament from the fluid chamber through the injection conduit, arid a volume-control mechanism operable to control a fraction of the first volume of medicament that is injected when the firing mechanism is actuated to inject the medicament.
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公开(公告)号：US12115360B2
公开(公告)日：2024-10-15
申请号：US17256243
申请日：2019-07-22
申请人： AMGEN INC.
CPC分类号： A61M5/3204 , A61M5/20 , A61M2005/2013 , A61M2005/208 , A61M2005/3107
摘要： Drug delivery devices are described that provide hybrid forms with gripping and stability functionalities, such as a grip portion on a skin contact surface. In some versions, the drug delivery devices can include a cep having a release liner such that removal of the cap exposes the grip portion. In some versions, the drug delivery devices include a retractable needle guard having the grip portion extending therearound.
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公开(公告)号：US12115358B2
公开(公告)日：2024-10-15
申请号：US16981328
申请日：2019-03-22
申请人： Novo Nordisk A/S
CPC分类号： A61M5/31595 , A61M5/2033 , A61M5/31526 , A61M5/3202 , A61M2005/3126
摘要： A drug delivery device includes a dose counting mechanism and an end-of-content or remaining-dose indication. For example, a dose expelling mechanism is coupled to a reciprocating element configured to undergo a predefined motion during each dose expelling action to allow a dose to be expelled. The predefined motion includes displacement in a first axial direction from a first position to a second position followed by displacement in a second axial direction from the second position to the first position, with a counter element being movable in the first axial direction. First and second unidirectional ratchet mechanisms prevent motion in the first axial direction and allow motion in the second axial direction of the reciprocating element relative to the counter element, and vice versa, respectively.
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公开(公告)号：US12115353B2
公开(公告)日：2024-10-15
申请号：US17102958
申请日：2020-11-24
发明人： Robert J. Dyer , Carl Tappan , Eric VanWyk
CPC分类号： A61M5/3007 , A61M5/1452 , A61M5/16877 , A61M5/172 , A61M5/20 , A61M5/48 , A61M2205/3327
摘要： An apparatus for injectate delivery includes a cartridge, a linear actuator, a rotary motor mechanically coupled the actuator, and a controller coupled to the motor. The controller controls a linear motion of the actuator by controlling an electrical input supplied to the motor in a first interval during which the motor is stationary with the linear actuator engaged with the cartridge to displace an injectate in the cartridge, a second interval following the first interval during which the controller accelerates the motor from stationary to a first speed selected to create a jet of the injectate from the cartridge with a velocity sufficient to pierce human tissue to a subcutaneous depth, a third interval during which the controller maintains the motor at or above the first speed, and a fourth interval during which the controller decelerates the motor to a second speed to deliver the injectate at the subcutaneous depth.
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公开(公告)号：US12109395B2
公开(公告)日：2024-10-08
申请号：US16764041
申请日：2018-11-15
申请人： SANOFI
发明人： Michael Schabbach , Claus Geiger , Andrea Heiberger , Dieter Kadereit , Charlotte Emma Harvey , Congyi Huang , Timothy Charles Frearson , Alexander David Norman
CPC分类号： A61M5/19 , A61J1/201 , A61J1/2093 , A61M5/2066 , A61M5/31596
摘要： The disclosure refers to a device, for example a cartridge, a syringe or an autoinjector, which reduces the possibility of user error and provides an easy and automatic operation during mixing and/or reconstitution. The device is adapted such that activation of the device causes movement one of a first piston and a second piston in second chamber in an axial direction of the device, thereby moving the other one of the first piston and the second piston into the same axial direction of the device, opening a fluid communication path between the second chamber and a first chamber of the device, and expelling a second material from the second chamber into the first chamber via the fluid communication path. The disclosure is further directed to a respective mixing and/or reconstitution method.
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公开(公告)号：US20240325651A1
公开(公告)日：2024-10-03
申请号：US18744036
申请日：2024-06-14
申请人： AMGEN INC.
CPC分类号： A61M5/3134 , A61M5/20 , A61M5/2033 , A61M5/31511 , F16F9/16 , F16F9/3228 , F16F9/3481 , F16F9/361 , A61M2005/2086 , A61M2005/3143 , A61M5/3243
摘要： An injection device, method, and system for drug delivery includes a primary container for storing a drug, the container having a stopper movably disposed in the container for expelling the drug, an injection drive mechanism comprising a plunger for acting on the stopper and an energy source for exerting a force on the plunger to cause the plunger to act on the stopper to expel the drug, the force causing the plunger to accelerate to a velocity prior to acting on the stopper, and a damping mechanism for reducing the velocity of the plunger prior to acting on the stopper. The damping mechanism can include a dashpot or an energy absorbing material associated with the plunger. Alternatively or additionally, the damping mechanisms can include absorbing material disposed between support members of an outer casing of the injection device and the primary container.
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公开(公告)号：US20240325642A1
公开(公告)日：2024-10-03
申请号：US18293959
申请日：2022-08-03
申请人： SHL Medical AG
CPC分类号： A61M5/2033 , A61M5/31578 , A61M2005/3131 , A61M2005/3142 , A61M2205/19 , A61M2207/00
摘要： A subassembly (100) of a medicament delivery device (102), the subassembly (100) comprising a housing (104) configured to contain a medicament container structure (250) from which medicament is expelled during use of the medicament delivery device (102), the housing (104) having a proximal end (106) and a distal end (108), and a drive assembly (110) comprising a plunger rod (124) at a proximal end (120) of the drive assembly (110), the plunger rod (124) being configured to, upon activation, apply an activating force on the medicament container structure (250) for expelling the medicament from the medicament delivery device (102), wherein the proximal end (106) of the housing (104) comprises an opening (112), and the distal end (108) comprises a sealable portion (114), wherein the drive assembly (110) is insertable into the housing (104) at the proximal end (106) to form the subassembly (100).
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公开(公告)号：US12102810B2
公开(公告)日：2024-10-01
申请号：US17831134
申请日：2022-06-02
发明人： Michael Helmer
CPC分类号： A61M5/3157 , A61M5/2033 , A61M2205/43 , A61M2205/581 , A61M2205/582 , A61M2207/00
摘要： The present disclosure relates to an audible indicator for use with a drug delivery device, the audible indicator including a spring element configured to reside in one of a relaxed state and a biased state, wherein the audible indicator includes a rotatable element coupled to the spring element, and wherein the spring element releases stored energy to rotate the rotatable element such that the rotatable element impacts a surface to generate an audible signal when the spring element changes from the biased state into the relaxed state.
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