Methods of Making and Using pH Modulating Compositions in the Reproductive System

    公开(公告)号:US20230346724A1

    公开(公告)日:2023-11-02

    申请号:US17300191

    申请日:2019-10-08

    Abstract: The present invention relates generally to compositions (e.g., gels, suppositories, and the like) and methods for modulating the acidity and/or alkalinity of the fluidic environment of human reproductive organs and systems (e.g., vagina, and cervical fluids/mucus). In particular, the compositions and methods of the present invention are useful for modulating the acidity and/or alkalinity of the fluids within the vagina and that bathe the mucosal surfaces therein. The compositions and methods are useful for promoting and/or sustaining colonization of the vagina by beneficial and/or typically nonpathogenic species of commensal microorganisms (e.g., bacterial species). Additionally, the compositions and methods are useful as adjuvants and/or carriers for introducing one or more species of beneficial commensal microorganisms (e.g., bacterial species) into the vagina such as lactic acid producing bacteria, and in particular, species of Lactobacilli.

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