公开(公告)号：US20250064709A1

公开(公告)日：2025-02-27

申请号：US18713993

申请日：2022-11-25

Applicant: DAICEL CORPORATION

Inventor： Hitomi MORIMOTO ,  Taro MORI ,  Hiroshi KOYAMA

IPC: A61K8/73 ,  A61K8/92 ,  A61Q19/00

Abstract: To provide a cellulose derivative having excellent affinity for various oil agents and a composition containing the cellulose derivative. A composition containing: a cellulose derivative and an oil agent, the cellulose derivative containing a monovalent organic group (La) that substitutes for at least some of hydrogen atoms constituting hydroxy groups in cellulose, the monovalent organic group (La) containing a hydrocarbon group having 6 or more carbons at a terminal, the monovalent organic group (La) containing no ether bond, and an average degree of substitution of the monovalent organic group (La) being 1.1 or greater. The oil agent is preferably at least one selected from the group consisting of a hydrocarbon oil, an ester oil, and a silicone oil.

公开(公告)号：US20250064706A1

公开(公告)日：2025-02-27

申请号：US18292037

申请日：2022-12-07

Applicant: Evonik Operations GmbH

Inventor： Stephan BRINKMANN ,  Martin SCHILLING ,  Anne BENEDIKT ,  Christina JOST ,  Tamara HEINZE

IPC: A61K8/64 ,  A61K47/18 ,  A61Q19/00 ,  C12N5/00

Abstract: Photostabilized compositions may include a water-soluble tyrosine-containing compound with a molecular weight of below 1 kDa and at least one photosensitive component. A method for stabilizing one or more photosensitive components may include the addition of a tyrosine-containing dipeptide with the one or more photosensitive components. The water-soluble tyrosine-comprising compound may be present at a concentration of at least 0.5 mM. The composition may be a culture medium.

公开(公告)号：US12233152B2

公开(公告)日：2025-02-25

申请号：US18447391

申请日：2023-08-10

Applicant: LOCUS SOLUTIONS IPCO, LLC

Inventor： Sean Farmer ,  Ken Alibek

IPC: A61K8/24 ,  A61K8/66 ,  A61K8/73 ,  A61K8/9728 ,  A61Q5/00 ,  A61Q19/00

Abstract: The subject invention provides materials and methods for improving facial skin, hair and scalp health using cosmetic yeast-based masks. In a specific embodiment, the subject invention provides a yeast-based mask for application to the face, which can improve the health and appearance of thereof. In another specific embodiment, the subject invention provides a yeast-based mask for application to the hair and scalp, which can aid in preventing hair loss, as well as improve the health and appearance of the hair and scalp. Methods of using the yeast-based masks are also provided.

公开(公告)号：US20250057754A1

公开(公告)日：2025-02-20

申请号：US18723425

申请日：2022-12-23

Applicant: DOW TORAY CO., LTD.

Inventor： Tsunehito SUGIURA ,  Mari WAKITA ,  Hiroko TANIGUCHI ,  Liyi TAN ,  Yasue KANZAKI ,  Kei NAGAYAMA ,  Hiro SETOGUCHI

IPC: A61K8/893 ,  A61K8/02 ,  A61K8/892 ,  A61Q19/00 ,  C07C69/675 ,  C08G77/16 ,  C08G77/18

Abstract: Provided are silicone elastomer particles having a crosslinked structure which is active with respect to biodegradability, and can provide texture and feel during use that is equal to or higher than conventional silicone elastomer particles when blended in a cosmetic composition or the like, a reactive group-containing polycaprolactone compound having a specific structure and useful as a raw material for synthesis reactions, and a method for producing the same. A polycaprolactone compound containing a reactive group having two or more modified polycaprolactone structures has the structural formula (1) as described herein, where in the formula, n is a number in the range 1 to 5 and Ra is a specific (meth)acryl terminal group or alkenyl terminal group, specifically, a compound selected from the aforementioned (meth)acryl-modified polycaprolactone compounds and alkenyl-modified polycaprolactone compounds.

公开(公告)号：US12226513B2

公开(公告)日：2025-02-18

申请号：US17852525

申请日：2022-06-29

Applicant: L'OREAL

Inventor： Jonathan Faig ,  Nicole Burkhard ,  David Chan ,  Susan Halpern Chirch

IPC: A61K8/44 ,  A61K8/04 ,  A61K8/34 ,  A61K8/368 ,  A61K8/49 ,  A61K8/73 ,  A61K8/81 ,  A61Q19/00

Abstract: The instant disclosure relates to a rheological-modifying and stabilizing polymer blend, cosmetic compositions comprising the polymer blend, and methods for stabilizing, for modifying viscosity, and for treating the skin using the polymer blend or using cosmetic compositions comprising the polymer blend. The rheological-modifying and stabilizing polymer blend comprises: (i) a carbomer; (ii) acrylates/C10-30 alkyl acrylate crosspolymer; and (iii) ammonium acryloyldimethyltaurate/steareth-25 methacrylate crosspolymer.

公开(公告)号：US12226423B2

公开(公告)日：2025-02-18

申请号：US17852142

申请日：2022-06-28

Applicant: Virginia Commonwealth University ,  Durect Corporation ,  The United States Government as Represented by the Department of Veterans Affairs

Inventor： Shunlin Ren ,  Leyuan Xu ,  Yanxia Ning ,  Jin Koung Kim ,  WeiQi Lin ,  Andrew R. Miksztal ,  Hongwei Wu ,  Min L. Lee

IPC: A61K31/565 ,  A61K8/63 ,  A61K8/73 ,  A61K9/00 ,  A61K9/19 ,  A61K31/575 ,  A61K31/724 ,  A61K47/10 ,  A61K47/40 ,  A61P1/16 ,  A61P3/06 ,  A61P17/06 ,  A61P31/04 ,  A61Q19/00 ,  C07J31/00

Abstract: Compositions comprising 5-cholesten-3, 25-diol, 3-sulfate (25HC3S) or pharmaceutically acceptable salt thereof and at least one cyclic oligosaccharide, e.g., a cyclodextrin (CD), are provided. The compositions may be used to prevent and/or treat a variety of diseases and conditions, including organ failure (e.g. acute liver failure), high cholesterol/high lipids, and various inflammatory diseases and conditions.

公开(公告)号：US20250049695A1

公开(公告)日：2025-02-13

申请号：US18722877

申请日：2022-12-20

Applicant: KAO CORPORATION

Inventor： Moeko ASANO ,  Hikaru TEZUKA ,  Shogo ISHIYAMA ,  Masanori TAKAI

IPC: A61K8/894 ,  A61K8/25 ,  A61K8/73 ,  A61Q19/00

Abstract: The present invention relates to a surface-coated particle in which a portion or all of the surface of a particle (A) is coated with a surface treatment agent (B), wherein a dynamic friction coefficient of the surface-coated particle is 0.50 or less, when a 5% by mass ethanol dispersion of the surface-coated particle is applied onto a polyurethane substrate in an amount of 2 mg/cm2, and dried for 24 hours under atmospheric pressure at 23° C., followed by measurement under conditions of a load of 3.53 N, a moving speed of 10 mm/sec, a moving distance of 50 mm, 30 reciprocations, and a temperature of 25±2° C., and the standard deviation of the dynamic friction coefficient is 0.020 or less.

公开(公告)号：US20250049683A1

公开(公告)日：2025-02-13

申请号：US18591891

申请日：2024-02-29

Applicant: Elise A. Olsen

Inventor： Mitchell A. deLong ,  Elise A. Olsen

IPC: A61K8/64 ,  A61K8/37 ,  A61K8/49 ,  A61K8/69 ,  A61K31/198 ,  A61K31/215 ,  A61K31/4439 ,  A61K31/585 ,  A61K31/7004 ,  A61K45/06 ,  A61Q5/02 ,  A61Q5/08 ,  A61Q7/00 ,  A61Q7/02 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/02 ,  A61Q19/10

Abstract: A method for inhibiting hair growth in mammals using compositions containing FP receptor antagonists (e.g., prostaglandin F analogs that are block activation of the FP receptor). The compositions can be applied topically to the skin and/or hair. The compositions can arrest hirsutism or hypertrichosis, reverse hirsutism and hypertrichosis, and further prevent hair growth. These compositions can also be used to protect hair from chemical or radiation-induced alopecia or hair loss. These compositions can also be used to inhibit pigmentation of the hair or skin.

公开(公告)号：US20250049662A1

公开(公告)日：2025-02-13

申请号：US18719945

申请日：2022-12-21

Applicant: L'OREAL

Inventor： Nathalie GUILLIER ,  Géraldine LEREBOUR

IPC: A61K8/34 ,  A61K8/44 ,  A61Q19/00

Abstract: The present invention relates to a composition, in particular cosmetic, comprising water and: i) at least one (C1-C6)(alkyl)vanillin, one of the organic or mineral basic salts thereof, or one of the solvates thereof such as hydrates; ii) at least one sequestering agent selected from the salts of formula (I) as well as the solvates thereof such as hydrates, and ethylene diamine disuccinic acid and the salts thereof, and iii) optionally at least one additional antimicrobial, preferably selected from C2 to C6 alkanols, C2 to C10 polyols, surfactants in particular non-ionic and mixtures thereof.

公开(公告)号：US20250049645A1

公开(公告)日：2025-02-13

申请号：US18290466

申请日：2022-04-25

Applicant: DAICEL CORPORATION

Inventor： Keiko KOBAYASHI ,  Sadaki TAKATA ,  Masaya OMURA

IPC: A61K8/02 ,  A61K8/19 ,  A61K8/27 ,  A61K8/73 ,  A61Q19/00

Abstract: A composition includes particles of a cellulose derivative and a surface treatment compound. The particles of the cellulose derivative have an average particle size from 0.08 μm to 100 μm. The surface treatment compound is an organic compound having a long-chain alkyl group and/or an inorganic powder. The inorganic powder has an average particle size of ⅓ or less of the average particle size of the particles of the cellulose derivative. A cosmetic composition includes the composition. A method for producing the composition includes mixing the particles of the cellulose derivative and the surface treatment compound. In the mixing, the particles of the cellulose derivative and the surface treatment compound are dry-mixed.