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公开(公告)号：US12102943B2
公开(公告)日：2024-10-01
申请号：US18258531
申请日：2021-12-21
发明人： Dean John Ackerman , Sean Goodwin
CPC分类号： B01D21/32 , B01D21/28 , G01N27/043
摘要： Method and apparatus are provided to select target metal particles from aggregate ore. A feed stream of aggregate is directed along a path and a higher density portion is segregated therefrom. Detectors are arranged in-line and along the flow of the higher density portion. High resolution detection of a target particles within the feed stream triggers ejection of a select portion of the feed stream and target particle as a concentrate and the balance continues to a further phase of detection/ejection. The concentrate is processed in further stages or collected as product. Multiple parallel detector/ejectors across the path can isolate target particles and minimize the ejected gangue portion associated therewith. Dry or hydrodynamic transport of the feed stream is available determined by aggregate characteristics. A compact footprint of the apparatus is achieved with arcuate paths and multi-level conveyance whilst low energy requirements enables use in artisan installations.
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公开(公告)号：US20240110908A1
公开(公告)日：2024-04-04
申请号：US18528061
申请日：2023-12-04
发明人： Jason O. Fiering , Kenneth T. Kotz
CPC分类号： G01N33/491 , A61M1/3678 , A61M1/3693 , B01D21/283 , B01L3/502753 , B03B1/04 , G01N15/02 , G01N15/06 , B01D2221/10 , B01L2400/0436 , G01N2015/0065
摘要： A method for separating particles in a biofluid includes pretreating the biofluid by introducing an additive, flowing the pretreated biofluid through a microfluidic separation channel, and applying acoustic energy to the microfluidic separation channel. A system for microfluidic separation, capable of separating target particles from non-target particles in a biofluid includes at least one microfluidic separation channel, a source of biofluid, a source of additive, and at least one acoustic transducer coupled to the microfluidic separation channel. A kit for microfluidic particle separation includes a microfluidic separation channel connected to an acoustic transducer, a source of an additive, and instructions for use.
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公开(公告)号：US11925893B2
公开(公告)日：2024-03-12
申请号：US17424471
申请日：2020-08-04
申请人： BEIHANG UNIVERSITY
发明人： Xiaodong Li , Jizhou Liu
CPC分类号： B01D49/006 , A61M1/3678 , B01D21/283 , B01J19/10 , B01L2300/0861 , B01L2400/0439 , C12N13/00
摘要： The present disclosure provides a device for separating sub-micron particles in the air, comprising a first separation channel, a second separation channel and a collection device which are connected in sequence, wherein each of the first separation channel and the second separation channel is of a rectangle structure with two open ends, the height H1 of the first separation channel is greater than the height H2 of the second separation channel, and each separation channel is provided with a vibration sound source and an antimicrobial coating layer. Based on the agglomeration theory of suspended particles in the air by ultrasonic standing waves, the device can aggregate sub-micron suspended particles flowing into each channel of the device on the upper and lower wall surfaces and the centerline of the channel, and sterilize the aggregated particles, thereby effectively removing the sub-micron suspended particles in the air.
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公开(公告)号：US20240003932A1
公开(公告)日：2024-01-04
申请号：US18343077
申请日：2023-06-28
发明人： Keita KUBO , Chikara KOJIMA , Mitsuru MIYASAKA , Yoshio ARAI , Hiroto TOMIOKA
CPC分类号： G01P5/241 , G01N1/2035 , C02F1/36 , C02F1/008 , B01D21/283 , B01D21/34 , C02F2209/40
摘要： A fluid device 10 includes: a flow path 20 through which a fluid containing a fine particle flows; an ultrasonic transmitter 60 configured to transmit an ultrasonic wave to the fluid in the flow path 20 in response to an input of a drive signal; a flow velocity measurement unit 40 configured to measure a flow velocity of the fluid in the flow path 20; and a controller 70 configured to control the ultrasonic transmitter 60. The controller 70 sets an amplitude of the drive signal according to a measured flow velocity that is a flow velocity measured by the flow velocity measurement unit 40, and inputs the drive signal having the set amplitude to the ultrasonic transmitter 60.
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公开(公告)号：US11807558B2
公开(公告)日：2023-11-07
申请号：US14947795
申请日：2015-11-20
申请人： SUEZ International
发明人： Peter Temple Ballard , Raed Labban
CPC分类号： C02F1/5236 , B01D21/01 , B01D21/267 , B01D21/28 , C02F1/56 , C02F1/385 , C02F1/72 , C02F2301/046 , C02F2303/18 , C02F2305/12
摘要： In general, the present invention is directed to systems and methods of providing improved ballasted clarification systems for the treatment of water or wastewater. In accordance with some embodiments, a method may include introducing an influent including the water or wastewater and a coagulant; agitating or mixing the influent causing flocs to develop; introducing polymer and ballast wherein the ballast has an aspect ratio of less than 1.15; agitating or mixing the influent causing the ballast to move through the influent and penetrate the flocs; agitation or mixing the flocs to cause larger flocs to form through collision of smaller flocs among the flocs; providing the influent into a clarifying tank having a bottom and a top, wherein the ballast particles in flocs cause the flocs to settle to the bottom of the clarifier; and outputting an effluent from the top of the clarifying tank.
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公开(公告)号：US20230218813A1
公开(公告)日：2023-07-13
申请号：US18121192
申请日：2023-03-14
CPC分类号： A61M1/3693 , B01D21/283 , B01D21/28 , A61M1/362 , A61M1/3692 , A61M1/3678 , B01D2221/10
摘要： Systems and methods for cleansing blood are disclosed herein. The methods include acoustically separating undesirable particles bound to capture particles from formed elements of whole blood. After introducing the capture particles to whole blood containing undesirable particles, the whole blood and capture particles are flowed through a microfluidic separation channel. At least one bulk acoustic transducer is attached to the microfluidic separation channel. A standing acoustic wave, imparted on the channel and its contents by the bulk acoustic transducer, drives the formed elements and undesirable particles bound to capture particles to specific aggregation axes. After aggregating the particles, the formed elements exit the separation channel through a first outlet and are returned to the patient. The undesirable particles, bound to the capture particles, exit through a second outlet and can be discarded to saved for later study.
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公开(公告)号：US20230071935A1
公开(公告)日：2023-03-09
申请号：US17884705
申请日：2022-08-10
摘要： A sonicator assembly, including: a microplate defining a plurality of wells; a manifold for containing a transducer fluid that is thermally coupled to the plurality of wells of the microplate; an ultrasonic generator operable for applying an ultrasonic excitation to the wells of the microplate; one or more of a heating module thermally coupled to and operable for selectively heating the transducer fluid and a cooling module thermally coupled to and operable for selectively cooling the transducer fluid; and a controller operable for controlling operation of the ultrasonic generator and the one or more of the heating module and the cooling module. The controller is further operable for monitoring a temperature and a pressure within the manifold. A temperature of the plurality of wells is controllable over a temperature range from 4° C. to 95° C. Optionally, the plurality of wells include a plurality of heat-resistant round-bottom hydrophilic wells.
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8.发明授权公开(公告)号：US11566978B2
公开(公告)日：2023-01-31
申请号：US16707552
申请日：2019-12-09
申请人： Hitachi, Ltd.
摘要： The object of the invention is to perform, rapidly and at a low cost, a pretreatment of an analysis sample containing a turbid substance. Provided is an analysis sample pretreatment apparatus in which a clarified liquid is obtained by removing a turbid substance from an analysis sample. The analysis sample pretreatment apparatus includes a cell configured to store the analysis sample, and a cell holder in which at least a part of a housing is opened to mount the cell. The cell holder includes an ultrasonic wave transducer and an ultrasonic wave reflection plate that are disposed on facing plane pairs while sandwiching the cell mounted inside the cell holder. The cell includes a first opening unit from which the analysis sample flows in, a second opening unit from which the clarified liquid flows out, and a third opening unit from which the turbid substance is discharged. In a state where the cell is mounted in the cell holder, the first opening unit is provided at a position lower than an upper end of the ultrasonic wave transducer in a vertical direction, or at a position higher than a lower end of the ultrasonic wave transducer in the vertical direction.
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公开(公告)号：US20230008026A1
公开(公告)日：2023-01-12
申请号：US17719307
申请日：2022-04-12
申请人： Duke University
发明人： Yuyang Gu , Tony Jun Huang
IPC分类号： B01L3/00 , G01N1/40 , C12Q1/6806 , G01N21/64 , B01D21/28
摘要： The present disclosure provides for acoustofluidic centrifuge systems that can enrich and separate nanoparticles disposed in a fluid, such as liquid droplets, in a fast and efficient manner. Exemplary systems include a sound wave generator, such as a pair of slanted interdigitated transducers, and a containment boundary, such as a PDMS ring. The sound wave generator can produce surface acoustic waves that are capable of driving droplets to spin in a manner that can separate different sized particles into groups. In some embodiments, the acoustofluidic centrifuge system can include a plurality of containment boundaries in fluid communication with each other, allowing particles to separate between the containment boundaries. Methods of operating such systems, including methods of isolating different exosome subpopulations, are also disclosed.
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公开(公告)号：US20220193663A1
公开(公告)日：2022-06-23
申请号：US17599703
申请日：2020-03-26
发明人： Xin Yang
摘要： The invention concerns a novel acoustofluidic device to separate acoustically active particles from fluids comprising a novel device arrangement for improved acoustic pressure and particle velocity; and a method of separating particles from a fluid comprising use of same.
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