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公开(公告)号：US20250032955A1
公开(公告)日：2025-01-30
申请号：US18361615
申请日：2023-07-28
Applicant: Varda Space Industries, Inc.
Inventor： Jeffrey Michael ANDERSON , Haley Coddington BAUSER , Larry Robin CHAN , Eric Douglas MILLER , Ami Sanat BHAVSAR , Kenneth Hoyt CONDON , Jordan Michael CROOM , Andrew Steven McCALIP , Adrian RADOCEA
IPC: B01D9/00
Abstract: Payload systems for processing chemical substances under various gravity levels, such as hypergravity and/or microgravity. The payload systems may include a hypergravity thermal payload system configured to enable melt or cooling of a sample under hypergravity. Alternatively, or in addition, the payload systems may include a gravity-independent thermal payload system for enabling melt or cooling of a sample under various gravity levels, such as microgravity. Alternatively, or in addition, the payload systems may include a hypergravity crystallization payload system configured to enable crystallization of a chemical substance under hypergravity. Alternatively, or in addition, the payload systems may include a gravity-independent crystallization system configured to enable crystallization of a chemical substance in various gravity levels, such as microgravity.
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公开(公告)号：US20250032954A1
公开(公告)日：2025-01-30
申请号：US18361625
申请日：2023-07-28
Applicant: Varda Space Industries, Inc.
Inventor： Jeffrey Michael ANDERSON , Haley Coddington BAUSER , Larry Robin CHAN , Eric Douglas MILLER , Ami Sanat BHAVSAR , Kenneth Hoyt CONDON , Jordan Michael CROOM , Andrew Steven McCALIP , Adrian RADOCEA
Abstract: Payload systems for processing chemical substances under various gravity levels, such as hypergravity and/or microgravity. The payload systems may include a hypergravity thermal payload system configured to enable melt or cooling of a sample under hypergravity. Alternatively, or in addition, the payload systems may include a gravity-independent thermal payload system for enabling melt or cooling of a sample under various gravity levels, such as microgravity. Alternatively, or in addition, the payload systems may include a hypergravity crystallization payload system configured to enable crystallization of a chemical substance under hypergravity. Alternatively, or in addition, the payload systems may include a gravity-independent crystallization system configured to enable crystallization of a chemical substance in various gravity levels, such as microgravity.
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公开(公告)号：US20250019367A1
公开(公告)日：2025-01-16
申请号：US18697948
申请日：2022-10-06
Applicant: Mirati Therapeutics, Inc.
Inventor： Michal Achmatowicz , Svitlana Kulyk , David Snead , Cheng Chen , Matthew Marx , Christopher Smith
IPC: C07D403/04 , B01D9/00 , B01D15/38 , C07B57/00
Abstract: The present invention relates to methods for separating enantiomers of 5-phenyl and 5-naphthyl substituted 4-(aminomethyl)-6-(1-methyl-1H-pyrazol-4-yl)phthalazin-1(2H)-ones using N-Boc-L-phenylalanine, N-Boc-D-phenylalanine, and similar chiral acids.
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公开(公告)号：US20250002364A1
公开(公告)日：2025-01-02
申请号：US18760935
申请日：2024-07-01
Applicant: Carbon Engineering ULC
Inventor： Kenton Robert Heidel , David William Keith , Jane Anne Ritchie , Nicholas Vollendorf , Eric Fessler
Abstract: Techniques for growing crystalline calcium carbonate solids such that the crystalline calcium carbonate solids include a volume of 0.0005 mm3 to 5 mm3, include a slaker to react quicklime (CaO) and a low carbonate content fluid to yield a slurry of primarily slaked lime (Ca(OH)2); a fluidized-bed reactive crystallizer that encloses a solid bed mass and includes an input for a slurry of primarily slaked lime, an input for an alkaline solution and carbonate, and an output for crystalline calcium carbonate solids that include particles and an alkaline carbonate solution; a dewatering apparatus that includes an input coupled to the crystallizer and an output to discharge a plurality of separate streams that each include a portion of the crystalline calcium carbonate solids and alkaline carbonate solution; and a seed transfer apparatus to deliver seed material into the crystallizer to maintain a consistent mass of seed material.
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公开(公告)号：US20240342091A1
公开(公告)日：2024-10-17
申请号：US18634454
申请日：2024-04-12
Inventor： Keith P. JOHNSTON , Joshua ENGSTROM , Robert O. WILLIAMS, III
CPC classification number: A61K9/1682 , A61K9/1658 , B01D9/005 , Y10T428/2982
Abstract: The present invention includes compositions and methods for preparing micron-sized or submicron-sized particles by dissolving a water soluble effective ingredient in one or more solvents; spraying or dripping droplets solvent such that the effective ingredient is exposed to a vapor-liquid interface of less than 50, 100, 150, 200, 250, 200, 400 or 500 cm−1 area/volume to, e.g., increase protein stability; and contacting the droplet with a freezing surface that has a temperature differential of at least 30° C. between the droplet and the surface, wherein the surface freezes the droplet into a thin film with a thickness of less than 500 micrometers and a surface area to volume between 25 to 500 cm−1.
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Patent Agency Ranking
公开(公告)号：US20240279192A1
公开(公告)日：2024-08-22
申请号：US18560771
申请日：2022-04-24
Applicant: B-FCTL CO., LTD.
IPC: C07D295/24 , B01D9/00 , D01F2/08 , D01F13/00
CPC classification number: C07D295/24 , B01D9/0004 , B01D9/0031 , B01D9/0036 , D01F2/08 , D01F13/00 , B01D2009/0086
Abstract: The invention discloses a purification method, system and a detection method of N-methylmorpholine N-oxide (NMMO), and a N-methylmorpholine N-oxide obtained thereof. The NMMO is derived from a NMMO crude product prepared by the reaction of N-methylmorpholine with hydrogen peroxide. The mass concentration of NMMO in the NMMO crude product is 50% to 60%. The purification method includes: performing cooling crystallization to the NMMO crude product between −20° C. and 78° C. to obtain crystalline NMMO. The NMMO purification method has a low cost, a high purity of the obtained NMMO product, and almost no generation of exhaust gas, waste water, and solid waste. Different from current NMMO purification process, the purification method of the invention does not require ion-exchange resin, thus completely solved problems of significant amount of wastewater with high concentration of salt and COD and spent ion-exchange resin caused by the regeneration of ion-exchange resin.
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公开(公告)号：US12054403B2
公开(公告)日：2024-08-06
申请号：US17027873
申请日：2020-09-22
Applicant: ROC WATER TECHNOLOGIES (PTY) LTD
Inventor： Johannes Philippus Maree
IPC: C02F1/22 , B01D9/00 , B01D61/02 , C02F1/44 , C02F101/10 , C02F103/10
CPC classification number: C02F1/22 , B01D9/0013 , B01D61/025 , C02F1/441 , B01D2317/02 , C02F2101/10 , C02F2103/10
Abstract: A water treatment process (10) includes, in a crystallisation stage (12), passing a saline water feed (16) through an elongate conduit kept in a cold environment at a temperature below the equilibrium freezing temperature of the saline water, forming a slurry of brine and ice crystals inside the conduit, and, in a separation stage (14), separating the ice crystals from a bulk of the brine, producing a brine stream (22) and an ice stream (26). The elongate conduit is of a material, or has an inner material layer in contact with the saline water and with the slurry of brine and ice crystals, with a thermal conductivity of less than 5 W/m·K and has a length configured to ensure formation of the slurry of brine and ice crystals in the conduit at the flow rate of the saline water feed through the elongate conduit.
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公开(公告)号：US20240238695A1
公开(公告)日：2024-07-18
申请号：US18558814
申请日：2022-05-05
Applicant: COOL SEPARATIONS B.V.
Inventor： Dirk Cornelis NOOTENBOOM , Jacob VAN SPRONSEN
CPC classification number: B01D9/0013 , B01D9/02 , B01D2009/0086
Abstract: A system is provided for performing crystallisation by cooling, comprising two crystallisation units, each of the two crystallisation units comprising a cooling body with a crystallisation surface for forming crystals on, and a scraper unit, comprising a scraping member arranged to be moved over the crystallisation surface for scraping crystals from the crystallisation surface and a scraper actuator for moving the scraping member over the crystallisation surface, wherein the scraper actuator of a first of the two crystallisation units can be actuated independently from a scraper actuator of a second of the two crystallisation units.
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公开(公告)号：US12017182B2
公开(公告)日：2024-06-25
申请号：US17507959
申请日：2021-10-22
Inventor： Chen Yang , Bingbing Qin , Yufeng Yang , Kai Wang , Xiucai Liu
IPC: B01D15/08 , B01D3/10 , B01D3/12 , B01D9/00 , B01D25/12 , B01D29/00 , B01D36/00 , B01D61/14 , B01D61/18 , B01D61/36 , B01D69/02
CPC classification number: B01D61/18 , B01D3/10 , B01D3/12 , B01D9/005 , B01D9/0068 , B01D15/08 , B01D25/12 , B01D29/00 , B01D36/00 , B01D61/145 , B01D61/147 , B01D61/149 , B01D61/364 , B01D69/02 , B01D2009/0086 , B01D2311/103 , B01D2311/106 , B01D2311/2626 , B01D2311/2642 , B01D2311/2649 , B01D2311/2669 , B01D2317/025 , B01D2325/0283 , B01D2325/20
Abstract: The present disclosure provides a system for refining long chain dicarboxylic acid, comprising: a first membrane filtration unit, for a first membrane filtration of a long chain dicarboxylic acid fermentation broth or a treated liquid therefrom; a first decolorization unit, for carrying out a first decolorization treatment to the filtrate obtained after the membrane filtration; a first acidification/crystallization unit, for carrying out a first acidification/crystallization of a filtrate obtained after the membrane filtration to give a solid-liquid mixture; a first separation unit, for a solid-liquid separation of the solid-liquid mixture; a drying unit, for drying the solid separated by the separation unit to give a first solid. By using the refining system according to the present disclosure, the purity of the obtained product is high, and the disadvantages such as poor quality of the product obtained by crystallization from a solvent and environment pollution caused by a solvent can be overcome.
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公开(公告)号：US20240165538A1
公开(公告)日：2024-05-23
申请号：US18283267
申请日：2022-03-15
Applicant: TSUKISHIMA KIKAI CO., LTD.
Inventor： Hiroya TSUZAKI , Shinichi YAMAMOTO , Yuma NAGASAWA , Tatsuya KAMBE
CPC classification number: B01D9/02 , B01D2009/0086
Abstract: A crystallization device (4) includes a stirring blade (W) including a plurality of radially penetrating holes (h) and rotating about a rotating shaft (3), a reaction tank (1) having a bottomed cylindrical shape and concentrically accommodating the stirring blade (W) inside, a first liquid supply portion (5a) provided on the reaction tank (1) and supplying a first reaction liquid (L1) to the inside of the reaction tank (1), and a second liquid supply portion (5b) provided on the stirring blade (W) and supplying a second reaction liquid (L2).
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