METHOD FOR MANUFACTURING DIARYLMETHANE COMPOUND

    公开(公告)号:US20210198231A1

    公开(公告)日:2021-07-01

    申请号:US17058908

    申请日:2019-05-30

    Inventor: Masahiko SEKI

    Abstract: An object is to provide a method for producing a compound which is useful as a synthetic intermediate for an active pharmaceutical ingredient of an antidiabetic drug or the like in an industrially inexpensive and efficient manner, and the present invention can achieve the object by reducing a compound (2) represented by the following formula (2): wherein R1, Ar, n and X are as mentioned herein in the presence of a titanium compound by using a reducing agent to produce a compound (1) represented by the following formula (1): wherein R1, Ar and n are the same as defined above.

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