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公开(公告)号:US11406964B2
公开(公告)日:2022-08-09
申请号:US17040572
申请日:2019-03-26
发明人: Stefan Wershofen , Anton Vidal-Ferran , José Luis Núñez Rico , Javier Perez-Ramirez , Begona Puertolas Lacambra , Amol P. Amrute
IPC分类号: B01J23/10 , B01J6/00 , B01J37/03 , B01J37/12 , C07C269/04 , C07C271/28
摘要: The present invention relates to a catalyst for preparing carbamates, in particular aromatic carbamates, comprising a binary oxide having the formula L1-xMxO2, wherein L is a metal selected from the lanthanoid series and M is a metal selected from the group consisting of Sc, Y, Ti, Zr, Hf, metals from the lanthanoid series and metals from the actinoid series, and wherein x ranges from 0.01 to 0.05. The present invention also relates to a method for producing said catalysts and a method of utilizing said catalysts in the production of carbamates, in particular aromatic carbamates.
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公开(公告)号:US20220017456A1
公开(公告)日:2022-01-20
申请号:US17291099
申请日:2019-11-07
发明人: Takenori ISHIZAWA
IPC分类号: C07C269/04 , C07D291/04 , C07C227/18 , C07D333/16 , C07D291/06
摘要: It was discovered that a cyclic sulfamidate can be produced by reacting an amino acid derivative with a cyclization reagent. In addition, it was discovered that an O-substituted serine derivative can be produced by reacting a cyclic sulfamidate with an alcohol.
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公开(公告)号:US20220002236A1
公开(公告)日:2022-01-06
申请号:US16768866
申请日:2018-11-19
发明人: Ji Hoon PARK , Tae Sun CHANG , Young Woo YOU , lljeong HEO , Jin Hee LEE , Seul Gi HAN , Kwan Yong JEONG
IPC分类号: C07C269/04 , B01J23/10 , B01J23/44
摘要: The present invention relates to a method of directly preparing a dicarbamate compound from a diamine compound, and more particularly to a method of directly preparing a dicarbamate compound by reacting a diamine compound with an alcohol compound in the presence of a mixed gas of carbon monoxide (CO) and oxygen (O2) using a Pd/MOx catalyst configured such that a palladium (Pd) active metal is supported on a metal oxide or metalloid oxide carrier.
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4.
公开(公告)号:US20200368675A1
公开(公告)日:2020-11-26
申请号:US16959436
申请日:2019-09-24
申请人: Tiangong University
发明人: Qingsong ZHANG , Xiaopeng LI , Yunfei LI , Juan ZHANG , Yirong CAI , Anan LI , Xuedong JIN , Pengfei LIU , Li CHEN
IPC分类号: B01D53/14 , C07C269/04
摘要: Disclosed in the present disclosure are a low energy consumption anhydrous CO2 phase change absorption agent, and a regeneration method and an application thereof, the absorption agent using a unitary diamine with a primary amine (NH2—) and a tertiary amine (—N—), and not containing any other organic solvent, water, and ionic liquid; two alkyl branches are linked to a nitrogen atom of the tertiary amine, forming a certain hydrophobicity; after absorbing the CO2, the diamine changes from a liquid phase to a solid phase, undergoing liquid-solid phase change to form white amino formate crystals.
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5.
公开(公告)号:US20200317602A1
公开(公告)日:2020-10-08
申请号:US16378152
申请日:2019-04-08
发明人: Lain-Tze LEE , Hui-Ping TSAI , Shu-Fen HUANG , Yi-Wen LIN , Pi-Tsan HUANG , Ying-Ying WU , Mei-Hui CHEN , Li-Jie HSU
IPC分类号: C07C69/24 , C07C67/313 , C07C69/94 , C07C69/635 , C07C271/22 , C07C235/74 , C07C235/76 , C07C235/84 , C07C269/04 , C07C231/02 , A61P9/10
摘要: The present invention discloses a novel 3-aryl-2-propen-1-one series derivative and the synthesis processes thereof. Besides, the present invention also discloses the series derivative as a pharmaceutical composition and their use for promoting myocardial regeneration.
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公开(公告)号:US10759743B2
公开(公告)日:2020-09-01
申请号:US16344092
申请日:2017-10-19
发明人: Jin-Quan Yu
IPC分类号: C07C211/35 , C07C211/03 , C07C269/04 , C07D215/12 , C07C209/68 , C07D213/40 , C07D213/61 , C07B37/04 , B01J31/22 , C07D213/64 , C07D241/42 , C07D319/18 , C07D333/22 , C07D471/04
摘要: Pd(II)-catalyzed g-G(sp3)-H arylation or heteroarylation of primary amines is realized by using 2-hydroxynicotinaldehyde as a catalytic transient directing group. Importantly, the catalyst and the directing group loading can be lowered to 2% and 4% respectively, thus demonstrating high efficiency of this newly designed transient directing group. Heterocyclic aryl iodides are also compatible with this reaction. Furthermore, swift synthesis of 1,2,3,4-tetrahydronaphthyridine derivatives is accomplished using this reaction.
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公开(公告)号:US10703714B2
公开(公告)日:2020-07-07
申请号:US16617144
申请日:2018-05-25
IPC分类号: C07C269/04 , B01J23/10 , B01J37/08 , B01J37/03 , B01J37/02 , B01J37/04 , C07C263/04 , C07C271/28
摘要: The present invention discloses a process for the synthesis of aromatic carbamates from amine with dialkyl carbonate in the presence of binary or ternary mixed metal oxide catalyst. The present invention further discloses the yield of said aromatic carbamate in the range of 60 to 99%. Further, the ratio of amine to dialkyl carbonate is in the range of 1:2 to 1:30.
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公开(公告)号:US10450265B2
公开(公告)日:2019-10-22
申请号:US15653591
申请日:2017-07-19
IPC分类号: C07C269/04 , C08G69/00 , C07C263/04 , C07C267/00 , C07C273/18 , C07C231/10 , C08G69/04 , C08G69/26 , C08G69/28 , C08G69/32
摘要: The present invention is directed to a process for preparing amides or polyamides by replacing isocyanate starting materials of a catalyzed thermal reaction with aromatic carbamates. Through the catalyzed thermal process involving a non-isocyanate precursor of the present invention, efficiency for producing amides or polyamides can be significantly improved, and the impure side products produced from a side reaction of isocyanate can be greatly curtailed. Hence, amides or polyamides of high purity and yield can be achieved. The invention also relates to a process for preparing aromatic carbamates, the new non-isocyanate precursors for amides or polyamides.
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公开(公告)号:US10414720B2
公开(公告)日:2019-09-17
申请号:US16076486
申请日:2017-06-12
IPC分类号: C07C231/02 , C07C269/04 , C07C269/06 , C07C237/00 , C07B51/00 , C07C237/22
摘要: The present invention relates to an improved process for the synthesis of (R)-Lacosamide in which free base of O-methyl-N-benzyl-D-Serinamide is not isolated before acylation. The process avoids the use of column chromatography and chiral resolution for the preparation of different stages of Lacosamide.
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公开(公告)号:US10385013B2
公开(公告)日:2019-08-20
申请号:US16191369
申请日:2018-11-14
发明人: Fei Liao , Gaobo Long , Hai Yang , Hu Feng
IPC分类号: C07C269/04 , C07C231/12 , C08G81/02 , C08F220/58 , C08F222/38 , C08F8/32 , C07C227/12 , C07C227/16 , C07C269/06 , C07C303/04 , C07C303/32 , C07C319/14 , C07C231/08 , C07D207/40 , C07C67/08 , C08G65/332 , C08G65/333 , C08G65/334
摘要: Micro-nano materials, products obtained by covalently modifying the surfaces of micro/nano materials with hydrophilic materials, and methods for making the same. The micro/nano materials on the surfaces have carboxyl groups or/and pro-carboxyl groups which are converted into their active esters. The products are covalently modified by forming amide bonds between the active esters on the surfaces and the modification agents; where the modification agents are hydrophilic compounds and/or hydrophilic polymers bearing primary and/or secondary aliphatic amines. Monomers bearing carboxyl groups and/or pro-carboxyl groups are used to produce an adequate number of carboxyl groups and/or pro-carboxyl groups on the surface of a polymer material to be modified. The carboxyl groups and/or pro-carboxyl groups are converted into active esters. A reasonably-sized modification agent bearing primary and/or secondary amines, zwitterions and hydrophilic linear spacer arms is used to form amide bonds and obtain a covalently modified surface layer.
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