公开(公告)号：US20240019779A1

公开(公告)日：2024-01-18

申请号：US17749880

申请日：2022-05-20

申请人： ROHM AND HAAS ELECTRONIC MATERIALS LLC

发明人： Li Cui ,  Emad Aqad ,  Yinjie Cen ,  Conner A. Hoelzel ,  James F. Cameron ,  Jong Keun Park ,  Suzanne M. Coley ,  Choong-Bong Lee

IPC分类号： G03F7/004 ,  C07C317/22 ,  C07C69/78

CPC分类号： G03F7/0045 ,  C07C317/22 ,  C07C2601/16 ,  C07C2601/08 ,  C07C69/78

摘要： A compound represented by Formula (1):




wherein X is a group having a valency of r; each R1 is independently an organic group comprising an acid-labile group; m is an integer greater than or equal to 1; k is an integer from 1 to 5; and r is an integer from 2 to 10, wherein the compound is non-polymeric, and wherein Ar1, L1, L2, R2, and R3 are as defined herein.

公开(公告)号：US11760735B2

公开(公告)日：2023-09-19

申请号：US17711205

申请日：2022-04-01

申请人： Novartis AG

发明人： Gary Glick ,  Shomir Ghosh ,  William R. Roush

IPC分类号： C07D263/46 ,  A61K31/41 ,  C07D333/34 ,  C07D405/12 ,  C07D417/12 ,  C07D295/096 ,  C07D213/34 ,  C07D307/64 ,  C07D311/54 ,  C07D213/71 ,  C07D277/36 ,  C07C317/22

CPC分类号： C07D263/46 ,  A61K31/41 ,  C07C317/22 ,  C07D213/34 ,  C07D213/71 ,  C07D277/36 ,  C07D295/096 ,  C07D307/64 ,  C07D311/54 ,  C07D333/34 ,  C07D405/12 ,  C07D417/12 ,  C07C2603/10

摘要： In one aspect, compounds of Formulae (I) and (II), or pharmaceutically acceptable salts thereof, are featured; Formula (I), Formula (II) or a pharmaceutically acceptable salt thereof, wherein the variables shown in Formulae (I) and (II) can be as defined anywhere herein.

公开(公告)号：US20230167053A1

公开(公告)日：2023-06-01

申请号：US17919080

申请日：2021-04-16

申请人： KUMIAI CHEMICAL INDUSTRY CO., LTD.

发明人： Yudai HOTTA

IPC分类号： C07C317/14 ,  C07C317/22 ,  C07C309/66

CPC分类号： C07C317/14 ,  C07C317/22 ,  C07C309/66

摘要： Provided are a methane-production inhibitor capable of inhibiting methane production for a long period of time, and a method for inhibiting methane production using the composition. A methane-production inhibitor composition contains one or more compounds selected from compounds represented by formula [I] as an effective ingredient, and a method for inhibiting methane production uses the composition.




(In formula [I], X represents an —OR1 group, a hydroxyl group, or a halogen atom, Y represents an —OR2 group or an —SO2R3 group, R1 represents a benzoyl group, R2 represents a methylsulfonyl group or a chloromethylsulfonyl group, and R3 represents a chloromethyl group or a hydroxymethyl group.)

公开(公告)号：US20230134776A1

公开(公告)日：2023-05-04

申请号：US17626519

申请日：2020-07-10

申请人： CANOPY GROWTH CORPORATION

发明人： SIAWASH AHMAR ,  KRISHNA KUMAR GNANASEKARAN ,  JEFFREY ALAN OMEARA ,  JI SUNG PARK

IPC分类号： C07C311/29 ,  C07D295/26 ,  C07C311/51 ,  C07C317/22 ,  C07C69/16 ,  C07D213/71 ,  C07C309/42 ,  C07D307/64 ,  C07D233/84 ,  C07D305/08 ,  C07D207/404 ,  C07D211/54 ,  C07D239/38 ,  C07D205/06 ,  C07D205/12 ,  C07D487/10 ,  C07D249/08 ,  C07D249/10 ,  C07D235/16 ,  C07D277/30 ,  C07D263/32

摘要： This disclosure relates to cannabinoid derivatives having the structure of formula (I), pharmaceutical compositions comprising them, and methods of using the cannabinoid derivatives in treating or preventing a diseases associated with a cannabinoid receptor in subject in need thereof, wherein the cannabinoid receptor is one or more of CB1, CB2, 5HT1A, 5HT2A, GPR18, GPR55, GPR119, TRPV1, TRPV2, PPARγ or a μ-opioid receptor.

公开(公告)号：US20220411364A1

公开(公告)日：2022-12-29

申请号：US17767188

申请日：2020-10-09

申请人： Heptares Therapeutics Limited

发明人： Miles Stuart Congreve ,  Nigel Alan Swain ,  Benjamin Whitehurst

IPC分类号： C07C233/55 ,  C07D257/04 ,  C07D305/06 ,  C07C311/51 ,  C07C317/22

摘要： The disclosures herein relate to novel compounds of formula (1): (1) and salts thereof, wherein A, X, R1, R2, R3, R4, R10 and R11 are defined herein, and their use in treating, preventing, ameliorating, controlling or reducing the risk of disorders associated with EP4 receptors.

公开(公告)号：US20220194885A1

公开(公告)日：2022-06-23

申请号：US17604522

申请日：2020-05-05

申请人： SOLVAY SPECIALTY POLYMERS ITALY S.P.A.

发明人： Rahul SHINGTE ,  Debaki GHOSH ,  Letanzio BRAGANTE ,  Manuel GREGORI ,  Stefano MILLEFANTI ,  Emanuela ANTENUCCI ,  Joel POLLINO

IPC分类号： C07C43/275 ,  C07C43/29 ,  C07C317/22 ,  C07D263/57 ,  C08G73/10

摘要： The invention pertains to a multi-step process for making polyfunctional aromatic compounds comprising two phenyl rings bearing reactive groups susceptible of polycondensation reaction to provide polycondensed polymers, said method using economic raw materials, and possessing high selectivity and overall yield.

公开(公告)号：US20220135574A1

公开(公告)日：2022-05-05

申请号：US17577139

申请日：2022-01-17

申请人： LG CHEM, LTD.

发明人： Young Kwan Kim ,  Sang Yun Park ,  Hyun Woo Joo ,  Eun Sil Choi ,  Seung Yup Paek ,  Seung Wan Kang ,  Byung Gyu Kim ,  Chang Seok Lee ,  Sung Wook Kim ,  Sang Dae Lee

IPC分类号： C07D487/04 ,  C07D401/04 ,  A61K31/4725 ,  C07C59/31 ,  C07C229/42 ,  C07C229/44 ,  C07C317/22 ,  C07D207/06 ,  C07D209/08 ,  C07D211/34 ,  C07D213/30 ,  C07D213/64 ,  C07D213/70 ,  C07D231/56 ,  C07D235/16 ,  C07D239/34 ,  C07D241/18 ,  C07D261/08 ,  C07D277/34 ,  C07D307/42 ,  C07D307/80 ,  C07D311/58 ,  C07D317/46 ,  C07D317/72 ,  C07D333/16 ,  C07D401/10 ,  C07D401/12 ,  C07D401/14 ,  C07D405/04 ,  C07D405/12 ,  C07D405/14 ,  C07D407/04 ,  C07D409/04 ,  C07D409/10 ,  C07D409/14 ,  C07D413/10 ,  C07D413/12 ,  C07D417/10

摘要： The present invention relates to a biaryl derivative expressed by the chemical formula 1, a method for producing the biaryl derivative, a pharmaceutical composition comprising same, and use of same, the biaryl derivative expressed by the chemical formula 1, as a GPR120 agonist, promoting GLP-1 generation in the gastro-intestinal tract, reducing insulin resistance in the liver, muscles and the like from anti-inflammatory activity in the macrophage, pancreatic cells and the like, and allowing effective use in prevention or treatment of inflammation or metabolic diseases such as diabetes, complications from diabetes, obesity, non-alcoholic fatty liver disease, fatty liver disease, and osteoporosis.

公开(公告)号：US20220064114A1

公开(公告)日：2022-03-03

申请号：US17500593

申请日：2021-10-13

申请人： TriOptoTec GmbH

发明人： Andreas SPÄTH ,  Anja EICHNER

IPC分类号： C07D213/30 ,  C07C49/755 ,  C07C69/56 ,  C07C69/76 ,  C07C211/62 ,  C07C233/18 ,  C07C233/20 ,  C07C317/22 ,  C07D303/18 ,  C07D309/14 ,  C07F7/02 ,  C07F7/18

摘要： A phenalene-1-one compound, a photosensitizer composition including the phenalene-1-one compound, an article including the phenalene-1-one compound and/or photosensitizer composition and the use thereof.

公开(公告)号：US11261186B2

公开(公告)日：2022-03-01

申请号：US15539310

申请日：2015-12-23

申请人： LG CHEM, LTD.

发明人： Young Kwan Kim ,  Sang Yun Park ,  Hyun Woo Joo ,  Eun Sil Choi ,  Seung Yup Paek ,  Seung Wan Kang ,  Byung Gyu Kim ,  Chang Seok Lee ,  Sung Wook Kim ,  Sang Dae Lee

IPC分类号： C07D239/34 ,  C07D401/10 ,  C07D403/10 ,  C07D471/04 ,  C07D487/04 ,  C07D401/04 ,  A61K31/4725 ,  C07C59/31 ,  C07C229/42 ,  C07C229/44 ,  C07C317/22 ,  C07D207/06 ,  C07D209/08 ,  C07D211/34 ,  C07D213/30 ,  C07D213/64 ,  C07D213/70 ,  C07D231/56 ,  C07D235/16 ,  C07D241/18 ,  C07D261/08 ,  C07D277/34 ,  C07D307/42 ,  C07D307/80 ,  C07D311/58 ,  C07D317/46 ,  C07D317/72 ,  C07D333/16 ,  C07D401/12 ,  C07D401/14 ,  C07D405/04 ,  C07D405/12 ,  C07D405/14 ,  C07D407/04 ,  C07D409/04 ,  C07D409/10 ,  C07D409/14 ,  C07D413/10 ,  C07D413/12 ,  C07D417/10

摘要： Compounds having the chemical formula 1, a method for producing the compounds of chemical formula 1, a pharmaceutical composition comprising same, and use thereof as a GPR120 agonist for prevention or treatment of inflammation or metabolic diseases such as diabetes, complications from diabetes, obesity, non-alcoholic fatty liver disease, fatty liver disease, and osteoporosis.

公开(公告)号：US11208378B2

公开(公告)日：2021-12-28

申请号：US16475637

申请日：2018-01-11

申请人： HONSHU CHEMICAL INDUSTRY CO., LTD.

发明人： Akihito Nasu

IPC分类号： C07C317/22

摘要： The present invention addresses the problem of providing a novel alkoxymethyl-substituted bisphenol compound having exceptional storage stability and exceptional solvent solubility, heat resistance, and optical properties when used as a resin raw material. This problem can be solved by using an alkoxymethyl-substituted bisphenol compound represented by General Formula (1): (wherein each R independently represents an alkyl group having 1 to 4 carbon atoms).