公开(公告)号：US20250000857A1

公开(公告)日：2025-01-02

申请号：US18826495

申请日：2024-09-06

Applicant: Albert Einstein College of Medicine ,  The University of Manitoba

Inventor： Evripidis Gavathiotis ,  Richard N. Kitsis

IPC: A61K31/496 ,  A61K31/495 ,  C07D209/86 ,  C07D209/88 ,  C07D279/26 ,  C07D295/13

Abstract: Compounds as inhibitors of Bcl-2-associated x-protein (BAX) and pharmaceutical compositions thereof are disclosed. Also disclosed are methods of using these compounds for preserving a tissue or treating a disease or disorder in which it is desirable to inhibit BAX.

公开(公告)号：US12178121B2

公开(公告)日：2024-12-24

申请号：US17445815

申请日：2021-08-24

Applicant: Samsung Display Co., Ltd.

Inventor： Hankyu Pak ,  Eunjae Jeong ,  Sanghyun Han ,  Dongjun Kim ,  Minji Kim ,  Sohee Jo

IPC: C07C211/61 ,  C07D209/86 ,  C07D209/88 ,  C07D333/76 ,  H10K85/60 ,  H10K50/15

Abstract: An organic electroluminescence device includes a first electrode, a hole transport region on the first electrode, an emission layer on the hole transport region, an electron transport region on the emission layer, and a second electrode on the electron transport region. The hole transport region may include an amine compound represented by Formula 1, thereby exhibiting high luminous efficiency:

公开(公告)号：US20240276872A1

公开(公告)日：2024-08-15

申请号：US18404236

申请日：2024-01-04

Applicant: ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD.

Inventor： So-Young JUNG ,  Tae-Jun HAN ,  YeJin JEON ,  Seung-Hyun YOON ,  Young-Jae KIM ,  Hyun-Ju KANG ,  Bitnari KIM ,  Sang-Hee CHO

IPC: H10K85/60 ,  C07D209/88 ,  C07D405/04 ,  C07D405/12 ,  C09K11/06

CPC classification number: H10K85/622 ,  C07D209/88 ,  C07D405/04 ,  C07D405/12 ,  C09K11/06 ,  H10K85/626 ,  H10K85/633 ,  H10K85/636 ,  H10K85/654 ,  H10K85/6574 ,  H10K2101/90

Abstract: The present disclosure relates to a plurality of host materials comprising at least one first host compound represented by Formula 1 and at least one second host compound represented by Formula 3 different from the first host compound, and an organic electroluminescent device comprising the same. By comprising a specific combination of compounds according to the present disclosure as host materials, an organic electroluminescent device having low driving voltage, high luminous efficiency, and/or significantly improved lifespan characteristic, can be provided.

公开(公告)号：US12035617B2

公开(公告)日：2024-07-09

申请号：US17246691

申请日：2021-05-02

Applicant: Samsung Display Co., Ltd.

Inventor： Hyun Shin ,  Sunwoo Kang ,  Jaejin Lyu ,  Yoonkyoo Lee ,  Jin-Won Sun ,  Jungsub Lee

IPC: H01L51/50 ,  C07D209/88 ,  C07D405/10 ,  C07F7/08 ,  C07F15/00 ,  C09K11/06 ,  H10K85/30 ,  H10K85/40 ,  H10K85/60 ,  H10K50/11 ,  H10K50/15 ,  H10K50/16 ,  H10K50/17 ,  H10K50/18 ,  H10K101/00 ,  H10K101/10

CPC classification number: H10K85/346 ,  C07D209/88 ,  C07D405/10 ,  C07F7/0812 ,  C07F15/0086 ,  C09K11/06 ,  H10K85/40 ,  H10K85/6572 ,  H10K85/6574 ,  C07B2200/05 ,  C09K2211/1018 ,  C09K2211/1044 ,  C09K2211/185 ,  H10K50/11 ,  H10K50/15 ,  H10K50/16 ,  H10K50/17 ,  H10K50/171 ,  H10K50/18 ,  H10K85/654 ,  H10K2101/10 ,  H10K2101/90

Abstract: An organic electroluminescence device includes: a first electrode; a second electrode facing the first electrode; and a plurality of organic layers disposed between the first electrode and the second electrode, wherein at least one organic layer of the plurality of organic layers includes a first compound represented by Formula 1, a second compound represented by Formula 2, and a third compound represented by Formula 3, wherein Formulae 1-3 are defined herein.

公开(公告)号：US20240199549A1

公开(公告)日：2024-06-20

申请号：US18430974

申请日：2024-02-02

Applicant: Universal Display Corporation

Inventor： Bin MA ,  Ting-Chih WANG ,  Vadim ADAMOVICH

IPC: C07D209/88 ,  H10K50/11 ,  H10K50/14 ,  H10K50/18 ,  H10K50/81 ,  H10K50/82

CPC classification number: C07D209/88 ,  H10K50/11 ,  H10K50/14 ,  H10K50/18 ,  H10K50/81 ,  H10K50/82

Abstract: A composition comprising a first compound and a second compound, wherein the first compound has a formula selected from the group consisting of







wherein the second compound has the formula




is disclosed.

公开(公告)号：US20240174608A1

公开(公告)日：2024-05-30

申请号：US18279162

申请日：2022-03-11

Applicant: The General Hospital Corporation

Inventor： Changning Wang ,  Yulong Xu ,  Can Zhang ,  Rudolph E. Tanzi

IPC: C07D209/88 ,  A61K51/04 ,  C07B59/00

CPC classification number: C07D209/88 ,  A61K51/0446 ,  C07B59/002 ,  A61K2123/00 ,  C07B2200/05

Abstract: The present application provides radiolabeled tetrahydrocarbazole compounds that can be used as positron emission tomography imaging probes. Pharmaceutical compositions and methods of using these compounds for diagnosis and monitoring treatment of neurodegenerative diseases (such as Alzheimer's disease) are also provided.

公开(公告)号：US20240150289A1

公开(公告)日：2024-05-09

申请号：US18497531

申请日：2023-10-30

Applicant: Raziel Therapeutics Ltd.

Inventor： Sharon COHEN-VERED ,  Eran BLAUGRUND ,  Racheli GUETA ,  Alon BLOOMENFELD

IPC: C07D209/88

CPC classification number: C07D209/88 ,  C07B2200/13

Abstract: A crystalline carbazole derivative, pharmaceutical compositions thereof, and methods of treatment are provided herein.

公开(公告)号：US11939293B2

公开(公告)日：2024-03-26

申请号：US17954841

申请日：2022-09-28

Applicant: Universal Display Corporation

Inventor： Bin Ma ,  Ting-Chih Wang ,  Vadim Adamovich

IPC: C07D209/88 ,  H10K50/11 ,  H10K50/14 ,  H10K50/18 ,  H10K50/81 ,  H10K50/82

CPC classification number: C07D209/88 ,  H10K50/11 ,  H10K50/14 ,  H10K50/18 ,  H10K50/81 ,  H10K50/82

Abstract: A novel compound selected from







is disclosed.

公开(公告)号：US20240043394A1

公开(公告)日：2024-02-08

申请号：US18041193

申请日：2021-08-10

Applicant: Board of Trustees of Michigan State University

Inventor： Jetze J. Tepe ,  Sophia Staerz

IPC: C07D279/28 ,  C07D265/38 ,  C07D265/36 ,  C07D209/88 ,  C07D471/04 ,  C07D473/40 ,  C07D233/64 ,  C07D235/26 ,  C07D207/327 ,  C07D295/192

CPC classification number: C07D279/28 ,  C07D265/38 ,  C07D265/36 ,  C07D209/88 ,  C07D471/04 ,  C07D473/40 ,  C07D233/64 ,  C07D235/26 ,  C07D207/327 ,  C07D295/192

Abstract: Described herein are chlorpromazine, methods for making such compounds, and the use of such compounds in the treatment of cancer, an inflammatory disease or condition or neurodegenerative diseases, such as Parkinson's disease, Alzheimer's disease, Huntington's disease, and ALS.

公开(公告)号：US11839147B2

公开(公告)日：2023-12-05

申请号：US16101565

申请日：2018-08-13

Applicant: BEIJING SUMMER SPROUT TECHNOLOGY CO., LTD.

Inventor： Chuanjun Xia

IPC: C07C211/54 ,  C07C211/58 ,  C07C211/61 ,  C07C255/31 ,  C07C255/34 ,  C07C255/37 ,  C07C255/51 ,  C07C321/26 ,  C07C381/00 ,  C07D209/86 ,  C07D209/88 ,  C07D307/52 ,  C07D307/91 ,  C07D333/20 ,  C07D333/76 ,  C07D405/12 ,  C07D409/12 ,  C07D409/14 ,  C07D471/14 ,  C07D487/04 ,  C07D487/06 ,  C07D487/14 ,  C09K11/06 ,  H10K50/11 ,  H10K50/13 ,  H10K50/15 ,  H10K50/17 ,  H10K85/60

CPC classification number: H10K85/624 ,  C07C255/34 ,  C07C255/37 ,  C07C255/51 ,  C07C381/00 ,  H10K50/13 ,  H10K85/611 ,  H10K85/633 ,  H10K85/636 ,  H10K85/6572 ,  C07C2603/54 ,  H10K50/17 ,  H10K85/631

Abstract: Hole injection layer and charge generation layer containing a truxene based compound are disclosed for organic electronic devices. By applying the truxene based compound for the hole injection layer, low driving voltage, high efficiency and long lifetime of the device can be achieved. In addition, a P-type charge generation layer comprising the truxene based compound can be used in tandem OLEDs structure and can further improve the voltage, efficiency and lifetime of the device.