公开(公告)号：US20240294448A1

公开(公告)日：2024-09-05

申请号：US18571768

申请日：2022-06-10

申请人： BASF SE

发明人： Thomas SCHAUB ,  Mathias SCHELWIES ,  Viktoriia ZUBAR

IPC分类号： C07C29/149 ,  B01J31/18 ,  C07D307/92

CPC分类号： C07C29/149 ,  B01J31/189 ,  C07D307/92

摘要： A method for hydrogenating an ester of the general formula (III)






with molecular hydrogen to give the alcohols










at a temperature of 50 to 200° C. and a pressure of 0.1 to 20 MPa abs in the presence of a manganese(I) complex, in which the manganese complex comprises a tridentate ligand L with the general formula (II)










and comprises at least two carbonyl ligands.

公开(公告)号：US20240132439A1

公开(公告)日：2024-04-25

申请号：US18374838

申请日：2023-09-29

申请人： Semiconductor Energy Laboratory Co., Ltd.

发明人： Sachiko Kawakami ,  Kazuki KAJIYAMA

IPC分类号： C07C211/55 ,  C07D307/91 ,  C07D307/92 ,  C07D333/74 ,  C07D333/76 ,  C07D411/12 ,  H10K85/60

CPC分类号： C07C211/55 ,  C07D307/91 ,  C07D307/92 ,  C07D333/74 ,  C07D333/76 ,  C07D411/12 ,  H10K85/615 ,  H10K85/633 ,  H10K85/6574 ,  H10K85/6576

摘要： A highly heat-resistant organic compound with favorable hole-transport properties is provided. The organic compound is represented by General Formula (G1). In General Formula (G1), X represents a sulfur atom or an oxygen atom, and R21 to R25 and R27 to R30 each independently represent any one of hydrogen, halogen, a nitrile group, an alkenyl group, a vinyl group, an alkynyl group, an ethynyl group, a straight-chain alkyl group having 1 to 6 carbon atoms, a cycloalkyl group having 3 to 10 carbon atoms, an alkoxy group having 1 to 6 carbon atoms, an alkylsilyl group having 3 to 10 carbon atoms, an aryl group having 6 to 30 carbon atoms, and a heteroaryl group having 2 to 30 carbon atoms. Ar1 represents an aryl group having 6 to 30 carbon atoms or a heteroaryl group having 2 to 30 carbon atoms. Ar2 is represented by General Formula (G1-1).

公开(公告)号：US11858948B2

公开(公告)日：2024-01-02

申请号：US16766543

申请日：2019-03-12

申请人： Firmenich SA

发明人： Philippe Dupau ,  Lucia Bonomo ,  Laurent Kermorvan ,  Murielle Haldimann Sanchez

IPC分类号： C07F9/58 ,  C07F15/00 ,  C07C29/149 ,  B01J31/24 ,  B01J31/18 ,  C07B35/00 ,  C07D307/92

CPC分类号： C07F15/0053 ,  B01J31/189 ,  B01J31/2409 ,  C07B35/00 ,  C07D307/92 ,  C07F9/58 ,  B01J2231/641 ,  B01J2531/004 ,  B01J2531/821 ,  C07C29/149

摘要： Described herein are catalytic hydrogenation processes, using Ru complexes with tetradentate ligands of formula L in hydrogenation processes for the reduction of ketone, aldehyde, ester, or lactone into the corresponding alcohol or diol respectively. These processes use a ruthenium complex of formula (1) as defined herein.

公开(公告)号：US20230416209A1

公开(公告)日：2023-12-28

申请号：US18253384

申请日：2021-11-23

申请人： Health Research, Inc.

发明人： Steven HOCHWALD ,  Jianliang ZHANG

IPC分类号： C07D253/07 ,  C07D487/04 ,  C07C233/81 ,  C07D307/92 ,  C07D271/113 ,  C07D239/74 ,  C07D209/42 ,  C07D307/93 ,  C07D239/62 ,  C07D493/04 ,  C07D239/70 ,  C07C49/643 ,  C07D257/02 ,  C07D311/20 ,  C07D471/06 ,  C07C281/08 ,  C07D327/08 ,  A61K33/243 ,  A61P35/00 ,  A61K31/53 ,  A61K31/196 ,  A61K31/365 ,  A61K31/4245 ,  A61K31/517 ,  A61K31/404 ,  A61K31/515 ,  A61K31/37 ,  A61K31/122 ,  A61K31/55 ,  A61K31/4748 ,  A61K31/175 ,  A61K31/382

CPC分类号： C07D253/07 ,  C07D487/04 ,  C07C233/81 ,  C07D307/92 ,  C07D271/113 ,  C07D239/74 ,  C07D209/42 ,  C07D307/93 ,  C07D239/62 ,  C07D493/04 ,  C07D239/70 ,  C07C49/643 ,  C07D257/02 ,  C07D311/20 ,  C07D471/06 ,  C07C281/08 ,  C07D327/08 ,  A61K33/243 ,  A61P35/00 ,  A61K31/53 ,  A61K31/196 ,  A61K31/365 ,  A61K31/4245 ,  A61K31/517 ,  A61K31/404 ,  A61K31/515 ,  A61K31/37 ,  A61K31/122 ,  A61K31/55 ,  A61K31/4748 ,  A61K31/175 ,  A61K31/382 ,  C07C2603/40 ,  C07C2603/86

摘要： Provided are compounds and compositions that inhibit glucose-induced growth signaling and methods of using same. The compounds may be suitable to treat glycolytic cancers, such as, for example, esophageal squamous cell carcinoma (ESCC). The compounds may be used to inhibit or partially inhibit glucose-promoted tumor cell proliferation, NME-1 catalyzed histidine phosphorylation of FAK, and FAK interaction with RBI. The compounds may have the following structure:

公开(公告)号：US11856841B2

公开(公告)日：2023-12-26

申请号：US18169524

申请日：2023-02-15

申请人： DUK SAN NEOLUX CO., LTD. ,  SAMSUNG DISPLAY CO., LTD.

发明人： Ki Won Kim ,  Kyung Hwan Oh ,  Bu Yong Yun ,  Hyung Dong Lee ,  Jin Woo Shin ,  Soung Yun Mun ,  Jae Duk Yoo ,  Jung Geun Lee ,  Joon Gu Lee ,  Yeon Hwa Lee ,  Mi Kyung Kim ,  Ji Hyun Seo ,  Kwan Hee Lee

IPC分类号： C07C22/08 ,  H01L51/00 ,  H01L51/50 ,  H10K85/60 ,  H10K85/40 ,  C07D213/26 ,  C07D253/02 ,  C07C211/56 ,  C07D333/76 ,  C07D307/92 ,  C07C43/29 ,  C07C323/09 ,  C07F7/08 ,  C07D209/86 ,  C07D307/91 ,  C07D311/96 ,  C07D487/04 ,  C07D307/93 ,  H10K50/82

CPC分类号： H10K85/615 ,  C07C22/08 ,  C07C43/29 ,  C07C211/56 ,  C07C323/09 ,  C07D209/86 ,  C07D213/26 ,  C07D253/02 ,  C07D307/91 ,  C07D307/92 ,  C07D307/93 ,  C07D311/96 ,  C07D333/76 ,  C07D487/04 ,  C07F7/081 ,  C07F7/0816 ,  H10K85/40 ,  H10K85/60 ,  H10K85/622 ,  C07C2601/16 ,  C07C2602/10 ,  C07C2603/24 ,  C07C2603/42 ,  H10K50/82

摘要： Provided are a fluorinated compound for patterning a metal or an electrode (cathode), an organic electronic element using the same, and an electronic device thereof, wherein a fine pattern of the electrode is formed by using the fluorinated compound as a material for patterning a metal or an electrode (cathode), without using a shadow mask, and it is possible to more easily apply UDC since it is easy to manufacture a transparent display having high light transmittance.

公开(公告)号：US20230357809A1

公开(公告)日：2023-11-09

申请号：US18322167

申请日：2023-05-23

申请人： Givaudan SA

发明人： Ghislain SANHAJI ,  Alix ROUSSEAUX ,  Sandrine NOEL ,  Eric EICHHORN

IPC分类号： C12P17/04 ,  C07D307/92 ,  A61Q13/00

CPC分类号： C12P17/04 ,  C07D307/92 ,  A61Q13/00 ,  C07B2200/07 ,  C07B2200/13 ,  C12Y504/99017

摘要： A solid form of (−)-Ambrox formed by a bioconversion process.

公开(公告)号：US20210395283A1

公开(公告)日：2021-12-23

申请号：US17053820

申请日：2019-04-29

申请人： JIANGSU OXIRANCHEM CO., LTD

发明人： Jianmin Zhu ,  Zhaobin Liu ,  Zhenpeng Dong

IPC分类号： C07F15/00 ,  C07F15/02 ,  C07F15/04 ,  C07D307/92 ,  C08F10/02 ,  C08F4/70

摘要： The present disclosure provides a compound, a complex, a preparation method thereof, and a use thereof. The compound is represented by the following structural formula, in which R1 to R10 are the same or different and are each independently selected from hydrogen, a hydrocarbon group having a carbon number of C1 to C16, a substituted hydrocarbon group, an alkoxy group, an alkylthio group, an alkylamino group, a haloalkylthio group, a halogen-substituted alkoxy group, a halogen-substituted alkylamino group, an aryloxy group, an arylthio group, arylamino group, a diphenylphosphino group, a halogen group, a nitro group, or a nitrile group. The complex of one embodiment of the present disclosure has a high catalytic effect, and can be used to prepare a highly branched, controllable, low molecular weight polymer with a high activity.

公开(公告)号：US11192873B2

公开(公告)日：2021-12-07

申请号：US16487161

申请日：2018-02-13

申请人： BASF SE

发明人： Mathias Schelwies ,  Rocco Paciello ,  Ralf Pelzer ,  Wolfgang Siegel

IPC分类号： C07C51/12 ,  C07C57/02 ,  C07D307/92

摘要： The present invention relates to a process for carbonylating allyl alcohols at low temperature, low pressure and/or low catalyst loading. In an alternative embodiment, an acylation product of the allyl alcohol is used for the carbonylation. The present invention likewise relates to the preparation of conversion products of these carbonylation products and specifically of (−)-ambrox.

公开(公告)号：US20210107883A1

公开(公告)日：2021-04-15

申请号：US16464413

申请日：2017-11-29

申请人： Sumitomo Dainippon Pharma Oncology, Inc.

发明人： Jeevanandam Arumugasamy ,  Wei LI

IPC分类号： C07D307/92 ,  C07C249/02

摘要： Provided herein are methods of preparation of I by reacting i with acid where R1 and R2 are each independently a leaving group. Intermediates to make i are also claimed.

公开(公告)号：US20210024482A1

公开(公告)日：2021-01-28

申请号：US16875479

申请日：2020-05-15

申请人： Sumitomo Dainippon Pharma Oncology, Inc.

发明人： Chiang Jia Li ,  Harry Rogoff ,  Youzhi Li ,  Jifeng Liu ,  Wei Li

IPC分类号： C07D307/92 ,  A61K31/38 ,  A61K31/343 ,  A61P35/00 ,  C07D333/74

摘要： The present invention relates to the use of a novel class of cancer stem cell pathway (CSCP) inhibitors; to methods of using such compounds to treat refractory, recurrent, or metastatic cancers; to methods of selective killing cancer cells by using such corn pounds with specific administration regimen; to methods of targeting cancer stem cells by inhibiting Stat3 pathway; to methods of using novel compounds in the treatment of conditions or disorders in a mammal related to aberrant Stat3 pathway activity; and to processes for preparing such compounds and intermediates thereof and to the pharmaceutical compositions of relevant compounds, and to the specific methods of administration of these compounds.