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1980 条记录 (耗时 0.036 秒)

    HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME
    3.
    发明公开
    HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME 审中-公开

    公开(公告)号：US20240237516A1

    公开(公告)日：2024-07-11

    申请号：US18512180

    申请日：2023-11-17

    申请人： LT MATERIALS CO., LTD.

    发明人： Dong Jin LEE ,  Won Jang JEONG ,  Dong Jun KIM ,  Dae Hyuk CHOI

    IPC分类号： H10K85/60 ,  C07D313/06 ,  C07D407/12 ,  C07D409/12 ,  C09K11/06

    CPC分类号： H10K85/636 ,  C07D313/06 ,  C07D407/12 ,  C07D409/12 ,  C09K11/06 ,  H10K85/633 ,  H10K50/15

    摘要： The present specification relates to a heterocyclic compound represented by the following Chemical Formula 1 and an organic light emitting device including the same:






    in Chemical Formula 1,
    R1 to R3 are the same as or different from each other, and each independently selected from the group consisting of hydrogen; deuterium; halogen; a cyano group; a substituted or unsubstituted C1 to C60 alkyl group; a substituted or unsubstituted C2 to C60 alkenyl group; a substituted or unsubstituted C2 to C60 alkynyl group; a substituted or unsubstituted C1 to C60 alkoxy group; a substituted or unsubstituted C3 to C60 cycloalkyl group; a substituted or unsubstituted C2 to C60 heterocycloalkyl group; a substituted or unsubstituted C6 to C60 aryl group; a substituted or unsubstituted C2 to C60 heteroaryl group; and a group represented by the following Chemical Formula 2,
    any one of R1 to R3 is the group represented by the following Chemical Formula 2, however, the remaining two are not the group represented by the following Chemical Formula 2,
    a and b are each independently an integer of 0 or 1, and satisfy a+b=1,
    m is one of integers of 1 to 4,
    when a or b is 0, n1 or n2 is each independently one of integers of 1 to 4, and
    when a or b is 1, n1 or n2 is each independently one of integers of 1 to 6,










    in Chemical Formula 2,
    L1, L2 and L3 are the same as or different from each other, and each independently a single bond; a substituted or unsubstituted C6 to C60 arylene group; or a substituted or unsubstituted C2 to C60 heteroarylene group,
    Ar1 and Ar2 are the same as or different from each other, and each independently a substituted or unsubstituted C6 to C60 aryl group; or a substituted or unsubstituted C2 to C60 heteroaryl group, and
    p, q and r are the same as or different from each other, and each independently an integer of 0 to 3.

    TARGETED DELIVERY OF 1,2,4,5 TETRAOXANE COMPOUNDS AND THEIR USES
    9.
    发明公开
    TARGETED DELIVERY OF 1,2,4,5 TETRAOXANE COMPOUNDS AND THEIR USES 审中-公开

    公开(公告)号：US20240101584A1

    公开(公告)日：2024-03-28

    申请号：US18266936

    申请日：2022-01-29

    申请人： Westlake University

    发明人： Dan YANG ,  Ming Kwan WONG

    IPC分类号： C07F9/655 ,  A61K45/06 ,  A61P35/00 ,  C07D323/04 ,  C07D405/12 ,  C07D407/12 ,  C07H13/12

    CPC分类号： C07F9/65522 ,  A61K45/06 ,  A61P35/00 ,  C07D323/04 ,  C07D405/12 ,  C07D407/12 ,  C07H13/12

    摘要： 1, 2, 4, 5-tetraoxane compounds and derivatives thereof that have anticancer properties are disclosed. Pharmaceutical compositions and pharmaceutical formulations in unit dosage form suitable for the delivery of the compounds to a subject in need thereof are disclosed. The pharmaceutical compositions or formulations may include one or more active agents in addition to the compounds, such as one or more additional anticancer agents. Methods for treating a cancer, reducing a cancer, or treating or ameliorating one or more symptoms associated with a cancer in a subject are also disclosed. The methods include (i) administering to a subject in need thereof an effective amount of the compound (s). The compound (s) can be administered by oral administration, parenteral administration, inhalation, mucosal administration, or a combination thereof. The compound can selectively kill cancer cells and/or cancer stem cells over non-cancerous cells by triggering ferroptosis in the cancer cells and/or cancer stem cells.