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48 条记录 (耗时 0.014 秒)

    Hydrolysis of ribonucleic acid containing material
    1.
    发明授权
    Hydrolysis of ribonucleic acid containing material 失效
    含有抗坏血酸的物质的水解

    公开(公告)号：US3830798A

    公开(公告)日：1974-08-20

    申请号：US5789570

    申请日：1970-06-18

    申请人： RALSTON PURINA CO

    发明人： HERNDON B ,  SCHNEIDER E

    IPC分类号： A23K1/00 ,  A23K1/16 ,  A23L1/229 ,  C07H1/08 ,  C07D51/50

    CPC分类号： C07H1/08 ,  A23K10/10 ,  A23K20/153 ,  A23L27/23 ,  Y10S426/805

    摘要： DOG FOOD COMPOSITIONS WHICH EXHIBIT ENHANCES FLAVOUR AND ACCEPTABILITY WHEN FED TO DOGS CONTAIN SMALL AMOUNTS, ON THE ORDER OF 4 PARTS PER MILLION AND UP, OF A RIBONUCLESOIDE, SUCH AS ADENOSINE, A 2'',3''-RIBONUCLEOTIDE, A SUCH AS 2,3''-URIDYLIC ACID, A POLY-2'',3''-RIBONUCLEOTIDE, A CHEMICALLY HYDROLYZED RIBONUCLEIC ACID-CONTAINING MATERIAL AND/OR CERTAIN OTHER STRUCTURALLY RELATED COMPOUNDS SUCH AS URIC ACID ,URACIL, PYRIMIDINE AND PURINE, AND SALTS AND MIXTURES OF SUCH MATERIALS AND THE LIKE. ENHANCEMENT OF THE FLAVOUR AND ACCEPTABILITY OF SUCH DOG FOOD COMPOSITIONS MAY BE FURTHER IMPROVED BY INCUDING A GLUTAMIC ACID SALT, SUCH AS MONOSODIUM GLUTAMATE. THE COMPOSITIONS MAY BE STABILIZED AGAINST DETERIORATIONS OF THE ENBILIZNG AGENT SUCH AS SODIUM TRIPOLYPHOSPHATE OR A SALT BILIZING AGENT SUCH AS SODIUM TRIPOLYPHOSPHATE OR A SALT OF ETHYLENEDIAMINETETRAACETIC ACID. THE FLAVOR ENHANCING MATERIALS MAY BE ADDED TO CONVENTIONAL DOG RATIONS IN AN AQUEOUS MEDIUM AT THE TIME OF FEEDING OR MAY BE SPRAYED ONTO OR OTHERWISE ADDED TO DOG RATIONS DURING PROCESSING THEREOF. RIBONUCLEIC ACID-CONTAINING MATERIALS, SUCH AS YEASTT MATERIALS, MAY BE SUBJECTED TO CHEMICAL HYDROLYSIS AT A PH ABOVE 12 AND A TEMPERATURE OF 25-55* C. FOR PERIODS OF THREE OR MORE HOURS TO PRODUCE HYDROLYZATE MATERIALS USEFUL FOR ENHANCING THE FLAVOUR AND ACCEPTABILITY OF DOG FOODS.

    5-Substituted 1,2,4-triazole-3-carboxamido nucleosides and analogs thereof
    6.
    发明授权
    5-Substituted 1,2,4-triazole-3-carboxamido nucleosides and analogs thereof 失效
    5-取代的1,2,4-三唑-3-甲酰氨基核苷及其类似物

    公开(公告)号：US3897415A

    公开(公告)日：1975-07-29

    申请号：US29292972

    申请日：1972-09-28

    申请人： ICN PHARMACEUTICALS

    发明人： ROBINS ROLAND K ,  WITKOWSKI JOSEPH T

    IPC分类号： C07H19/04 ,  C07D51/50

    CPC分类号： C07H19/04

    摘要： Disubstituted 1,2,4-triazole nucleosides, e.g., those of structure

    WHEREIN R is hydrogen or acyl and X and Y are differently selected from the group consisting of halogen, carboxamide and carboxylic acid ester groups are prepared by a method comprising fusion of an appropriately substituted 1,2,4-triazole with a tetra-O-acyl blocked ribofuranose. Disubstituted 1,2,4-triazole nucleosides prepared according to the invention have variously exhibited antimicrobial and antiviral activity in vitro, while others are useful in the preparation of such compounds.

    摘要翻译： 二取代的1,2,4-三唑核苷，例如结构化合物R为氢或酰基，X和Y不同地选自卤素，羧酰胺和羧酸酯基团的核苷，通过以下方法制备： 适当取代的1,2,4-三唑与四-O-酰基封端的呋喃核糖。 根据本发明制备的二取代的1,2,4-三唑核苷在体外各种各样地显示出抗微生物和抗病毒活性，而其它可用于制备这些化合物。

    Pyrazole compounds and process for preparing the same
    9.
    发明授权
    Pyrazole compounds and process for preparing the same 失效
    吡咯化合物及其制备方法

    公开(公告)号：US3598807A

    公开(公告)日：1971-08-10

    申请号：US3598807D

    申请日：1969-08-05

    申请人： KYOWA HAKKO KOGYO KK

    发明人： NAKAYAMA KIYOSHI ,  TANAKA HARUO

    IPC分类号： C07D231/38 ,  C07D51/50

    CPC分类号： C07D231/38 ,  C07H19/02 ,  C07H19/14

    摘要： 3(5)-AMINO-4-PYRAZOLE-CARBOXAMIDE, THE 1 - B-D-RIBOFURANOSIDE THEREOF AND THE 1-B-D-RIBOFURANOSIDE-5''-PHOSPHORIC ACID ESTER THEREOF ARE PREPARED BY HEATING THE CORRESPONDING 4-OXY-1H-PYRAZOLO(3,4-D)-PYRIMIDINE AND ITS DERIVATIVES AT A TEMPERATURE OF UP OT 180*C., PREFERABLY 100 -140*C., IN AN AQUEOUS SOLUTION HAVING AN ALKALINE PH, PREFERABLY 9.0-13.0. THE PRODUCTS DISPLAY ANTI-BACTERIAL ACTIVITY AND ARE USEFUL FOR THE STUDY OF NUCLEIC ACID METABOLISM.