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17 条记录 (耗时 0.011 秒)

    Pteridine derivatives and method
    1.
    发明授权
    Pteridine derivatives and method 失效
    吡啶衍生物和方法

    公开(公告)号：US3725408A

    公开(公告)日：1973-04-03

    申请号：US3725408D

    申请日：1971-07-06

    申请人： UNIV STRATHCLYDE

    发明人： WOOD H ,  STUART A

    IPC分类号： C07D209/48 ,  C07D57/28

    CPC分类号： C07D209/48

    摘要： A compound 2-amino-4-hydroxy-6-hydroxymethyl-7,7-dimethyl-7, 8dihydropteridine, or tautomeric forms thereof and pharmaceutically acceptable salts thereof. The compound is useful as a bacteriostat and in antibacterial products. The compound has useful activity against C1. perfringens and Derm. dermatonomous.

    摘要翻译： 化合物2-氨基-4-羟基-6-羟甲基-7,7-二甲基-7,8-二氢喋啶或其互变异构形式及其药物上可接受的盐。 该化合物可用作抑菌剂和抗菌产品。 该化合物对C1有效。 气管和皮肤。 皮肤病

    Synthesis of homopteroic and homofolic acid
    2.
    发明授权
    Synthesis of homopteroic and homofolic acid 失效
    合成和异烟酸的合成

    公开(公告)号：US3637695A

    公开(公告)日：1972-01-25

    申请号：US3637695D

    申请日：1968-03-20

    申请人： US HEALTH EDUCATION & WELFARE

    发明人： KIM YOUNG-HO ,  FRIEDMAN ORRIE M

    IPC分类号： C07D475/04 ,  C07D57/28

    CPC分类号： C07D475/04

    摘要： THE PRODUCTION OF HOMOPTEROIC AND HOMOFOLIC ACIDS BY VIRTUE OF SELECTING A CRITICAL KETO CONDENSING AGENT, NAMELY 1 - ACETOXY-4-(N-ACETY) - (P - CARBETHOXYPHENYL) AMINO)-2BUTANONE, WHICH IS CONDESED WITH A CONVENTIONAL PYRIMIDINE REACTANT, NAMELY 6-HYDROXY-2,4,5-TRIAMINOPYRIMIDINE, UNDER CONDITION OF NARROW PH CONTROL, PREFERABLY IN THE MILDLY ALKALINE RANGE 9.0-9.4.

    Process for the preparation of 1,3-dialkanoyl hexahydropyrimidine
    4.
    发明授权
    Process for the preparation of 1,3-dialkanoyl hexahydropyrimidine 失效
    1,3-二烷酰基六氢嘧啶的制备方法

    公开(公告)号：US3872120A

    公开(公告)日：1975-03-18

    申请号：US44842674

    申请日：1974-03-04

    申请人： US AGRICULTURE

    发明人： MOD ROBERT R ,  MAGNE FRANK C ,  SUMRELL GENE ,  NOVAK ARTHUR F ,  SOLAR JAMES M

    IPC分类号： C07D233/02 ,  C07D239/04 ,  C07D57/28 ,  C07D57/30

    CPC分类号： C07D239/04 ,  C07D233/02

    摘要： 1,3-Diacyl imidazolidines and hexahydropyrimidines were prepared by the reaction of formaldehyde and an N,N''-alkylenebisamide in the presence of a strong acid catalyst, the substituent acyl groups being acetyl, butyryl, pentanoyl, hexanoyl, heptanoyl, octanoyl, nonanoyl, decanoyl, palmitoyl, stearoyl, and oleoyl. These compounds exhibit antimycotic activity.

    摘要翻译： 1,3-二酰基咪唑烷和六氢嘧啶通过在强酸催化剂存在下甲醛与N，N'-亚烷基二甲酰胺的反应制备，取代基酰基为乙酰基，丁酰基，戊酰基，己酰基，庚酰基，辛酰基，壬酰基 癸酰基，棕榈酰基，硬脂酰基和油酰基。 这些化合物显示出抗真菌活性。

    2,7-di-(heterocyclic amino)-4-amino-6-phenyl-pteridines
    10.
    发明授权
    2,7-di-(heterocyclic amino)-4-amino-6-phenyl-pteridines 失效
    2,7-二 - （杂环氨基）-4-氨基-6-苯基 - P子

    公开(公告)号：US3557105A

    公开(公告)日：1971-01-19

    申请号：US3557105D

    申请日：1967-10-11

    申请人： BOEHRINGER SOHN INGELHEIM

    发明人： ROCH JOSEF

    IPC分类号： A61K31/00 ,  C07D475/08 ,  C07D57/28

    CPC分类号： A61K31/00 ,  C07D475/08 ,  Y10S514/929

    摘要： COMPOUNDS OF THE FORMULA

    2-R1,4-(R4-N(-R5)-),6-(C6H5-),7-R3-PTERIDINE

    WHEREIN R1 IS PYRROLIDINO OR 2''-METHYL-MORPHOLINO, R2 IS PYRROLIDINO, PIPERIDINO, 3''-HYDROXY-PIPERIDINO OR 2''-METHYL-MORPHOLINO, R4 IS B-HYDROXY-ETHYL, B-HYDROXY-N-PROPYL OR B, $-DIHYDROXY-N-PROPYL, AND R5 IS B-HYDROXY-N-PROPYL OR METHYL, WITH THE PROVISO THAT R1 AND R3 ARE NOT SIMULTANEOUSLY 2''-METHYL-MORPHOLINO, USEFUL AS CORONARY DILATORS IN WARM-BLOODED ANIMALS.