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    Phosphorescent four-coordinated platinum (II) complex
    3.
    发明授权
    Phosphorescent four-coordinated platinum (II) complex 有权
    磷光四配位铂（II）络合物

    公开(公告)号：US08722885B1

    公开(公告)日：2014-05-13

    申请号：US14099476

    申请日：2013-12-06

    申请人： National Tsing Hua University

    发明人： Yun Chi ,  Li-Min Huang

    IPC分类号： C07F15/00 ,  C07F9/547

    CPC分类号： C07F15/0086

    摘要： A phosphorescent four-coordinated platinum (II) complex represented by formula (C) is disclosed: where Y represents N or P; R1, R2, R3, R4, R5, R6, R9, R10, R11, and R12 are the same or different, and independently represent hydrogen, or a substituted or unsubstituted organic group; and represents or

    摘要翻译： 公开了由式（C）表示的磷光四配位铂（II）络合物：其中Y表示N或P; R 1，R 2，R 3，R 4，R 5，R 6，R 9，R 10，R 11和R 12相同或不同，独立地表示氢，或取代或未取代的有机基团; 代表或

    Dye including an anchoring group in its molecular structure
    4.
    发明授权
    Dye including an anchoring group in its molecular structure 有权
    染料在其分子结构中包括锚定基团

    公开(公告)号：US08440840B2

    公开(公告)日：2013-05-14

    申请号：US12738703

    申请日：2008-10-27

    申请人： Gerda Fuhrmann ,  Gabriele Nelles ,  Ameneh Bamedi Zilai ,  Akio Yasuda

    发明人： Gerda Fuhrmann ,  Gabriele Nelles ,  Ameneh Bamedi Zilai ,  Akio Yasuda

    IPC分类号： C07F9/02 ,  C07F9/547 ,  C07D209/02 ,  C07D209/04 ,  C07D209/12 ,  C07D209/14 ,  C07D209/18 ,  C08K5/00

    CPC分类号： H01G9/2059 ,  C09B57/007 ,  H01G9/2031 ,  H01G9/2063 ,  H01L51/0064 ,  H01L51/0068 ,  H01L51/0086 ,  Y02E10/542 ,  Y02E10/549

    摘要： A dye including an anchoring group in its molecular structure, said anchoring group allowing a covalent coupling of said dye to a surface, for example a surface of a nanoporous semiconductor layer, said anchoring group being represented by formula 1 wherein attachment of said anchoring group within said molecular structure of said dye is at the terminal carbon marked with an asterisk in above formula, wherein G is selected from —COOH, —SO3H, —PO3H2, —BO2H2, —SH, —OH, —NH2, preferably —COOH, wherein A is selected from the group comprising H, —CN, —NO2, —COOR, —COSR, —COR, —CSR, —NCS, —CF3, —CONR2-OCF3, C6H5-mFm, wherein m=1-5, R being H or any straight or branched alkyl chain of general formula —CnH2n+I, n=O-12, preferably 0-4, or any substituted or non-substituted phenyl or biphenyl.

    摘要翻译： 包含其分子结构中的锚定基团的染料，所述锚定基团允许所述染料与表面共价偶联，例如纳米多孔半导体层的表面，所述锚定基团由式1表示，其中将所述锚定基团连接在 所述染料的所述分子结构为在上式中带有星号的末端碳，其中G选自-COOH，-SO 3 H，-PO 3 H 2，-BO 2 H 2，-SH，-OH，-NH 2，优选-COOH，其中 A选自H，-CN，-NO 2，-COOR，-COSR，-COR，-CSR，-NCS，-CF 3，-CONR 2 -OCF 3，C 6 H 5 -m F m，其中m = 1-5，R 是H或通式-C n H 2n + I，n = O-12，优选0-4的任何直链或支链烷基链，或任何取代或未取代的苯基或联苯基。

    Ionic compound
    7.
    发明授权
    Ionic compound 失效
    离子化合物

    公开(公告)号：US07718826B2

    公开(公告)日：2010-05-18

    申请号：US12092729

    申请日：2006-10-12

    申请人： Masashi Otsuki ,  Hiroshi Kanno

    发明人： Masashi Otsuki ,  Hiroshi Kanno

    IPC分类号： C07F9/547

    CPC分类号： H01M10/0568 ,  C07F9/65815 ,  H01B1/122 ,  H01G9/2004 ,  H01M10/052 ,  Y02E10/542 ,  Y02E60/122 ,  Y02E60/13

    摘要： This invention relates to a novel ionic compound being low in a risk of combustion, and more particularly to an ionic compound represented by the following formula (I): (NPR12)n   (I) [wherein R1s are each independently a halogen element or a monovalent substituent, provided that at least one of R1s is an ionic substituent represented by the following general formula (II): —N+R23X−  (II) (wherein R2s are independently a monovalent substituent or hydrogen, provided that at least one of R2s is not hydrogen and R2s may be bonded with each other to form a ring; and X− is a monovalent anion); and n is 3 to 15].

    摘要翻译： 本发明涉及燃烧危险性低的新型离子化合物，更具体地说，涉及由下式（I）表示的离子化合物：（NPR 12）n（I）[其中R 1各自独立地为卤素元素或 一价取代基，条件是R 1中的至少一个是由以下通式（II）表示的离子取代基：-N + R 23 X - （II）（其中R 2独立地是一价取代基或氢，条件是R 2中的至少一个 不是氢，R2可以彼此键合形成环; X是一价阴离子）; n为3〜15]。

    Process for producing optically active phosphorus heterocyclic dimer
    8.
    发明授权
    Process for producing optically active phosphorus heterocyclic dimer 失效
    光学活性磷杂环二聚体的制备方法

    公开(公告)号：US07411096B2

    公开(公告)日：2008-08-12

    申请号：US10564985

    申请日：2004-07-27

    申请人： Nobuhiko Oohara ,  Tsuneo Imamoto

    发明人： Nobuhiko Oohara ,  Tsuneo Imamoto

    IPC分类号： C07F9/50 ,  C07F9/547

    CPC分类号： C07F9/65683 ,  C07F9/65685 ,  C07F15/008

    摘要： The present invention provides a process for producing an optically active phosphorus heterocyclic dimer including reacting, in the presence of a base, primary phosphine represented by formula (1) R—PH2   (1) is reacted with a compound represented by formula (2) Y—CnH2n—Y   (2) in the presence of a base; the product is reacted with boron trihydride, oxygen, or sulfur to obtain a phosphorus heterocyclic compound represented by formula (3): the resultant compound is dimerized to produce a phosphorus heterocyclic dimer represented by formula (4): and then oxygen, sulfur, or borane is removed from the resultant phosphorus heterocyclic dimer to obtain an optically active phosphorus heterocyclic dimer represented by formula (5):

    摘要翻译： 本发明提供一种光学活性磷杂环二聚体的制备方法，包括在碱的存在下，使由式（1）表示的主要膦与在线式描述=“In-line Formula”中的“ 引线“→R-PH <2>（1）<？in-line-formula description =”In-line Formulas“end =”tail“？>与式（2）表示的化合物反应 ）<？in-line-formula description =“In-line Formulas”end =“lead”？> YC H 2n-Y（2） line-formula description =“In-line Formulas”end =“tail”？>在一个基础的存在下; 将产物与三氢化硼，氧或硫反应，得到由式（3）表示的磷杂环化合物：所得化合物二聚以产生由式（4）表示的磷杂环二聚体：然后氧，硫或 从得到的磷杂环二聚体除去硼烷，得到式（5）表示的光学活性磷杂环二聚体：

    Indole-containing compounds with anti-tubulin and vascular targeting activity
    9.
    发明申请
    Indole-containing compounds with anti-tubulin and vascular targeting activity 审中-公开
    含吲哚的化合物具有抗微管蛋白和血管靶向活性

    公开(公告)号：US20070082872A1

    公开(公告)日：2007-04-12

    申请号：US10555352

    申请日：2004-05-03

    申请人： Kevin Pinney ,  Feng Wang ,  Mallinath Hadimani ,  Maria Mejia

    发明人： Kevin Pinney ,  Feng Wang ,  Mallinath Hadimani ,  Maria Mejia

    IPC分类号： A61K31/675 ,  C07F9/547 ,  A61K31/404 ,  C07D209/36

    CPC分类号： C07D209/12 ,  C07F9/247 ,  C07F9/5728

    摘要： Trimethoxyphenyl substituted indole ligands have been discovered which demonstrate impressive cytotoxicity as well as a remarkable ability to inhibit tubulin assembly. Such compounds as well as related derivatives are excellent clinical candidates for the treatment of cancer in humans. In addition, certain of these ligands, as pro-drugs, may well prove to be tumor selective vascular targeting chemotherapeutic agents or to have vascular targeting activity resulting in the selective prevention and/or destruction of nonmalignant proliferating vasculature.

    摘要翻译： 已经发现了三甲氧基苯基取代的吲哚配体，其表现出令人印象深刻的细胞毒性以及显着的抑制微管蛋白装配的能力。 这些化合物以及相关衍生物是用于治疗人类癌症的优异临床候选物。 此外，作为前药的这些配体中的某些可以很好地证明是肿瘤选择性血管靶向化学治疗剂或具有导致选择性预防和/或破坏非恶性增殖血管的血管靶向活性。