Specialty Fibrin Product
    6.
    发明公开

    公开(公告)号:US20230398264A1

    公开(公告)日:2023-12-14

    申请号:US18103102

    申请日:2023-01-30

    申请人: Fibrin, LLC

    摘要: The present invention is a specially prepared fibrin foam, and a method of (and equipment for) making it, which is flexible, contains either open cells, closed cells or both, and having individual cell diameters between 0.001 and 2 mm. Typical ratios of reactants, to give the desired foam characteristics, include 50 cc (45-55 cc) of whole blood (prior to separation to the plasma component) with the subsequent addition thereto of 2 ml (1.5-2.5 ml) 3% hydrogen peroxide, 5000 units (4500-5500 units) thrombin and 1 gm (0.9-1.1 g) calcium chloride in 3 cc (2-4 cc) water. The present invention also includes specialty vessels and constructs, namely, automated, or semi-automated inner containers for the non-blood reactants, and a custom outer separation vessel having a punted based with an annular base lip as well as an upper tube shape tapering inward towards its top annular opening.

    POLY(SARCOSINE) POLYMER EXCIPIENTS
    10.
    发明公开

    公开(公告)号:US20230142999A1

    公开(公告)日:2023-05-11

    申请号:US17985428

    申请日:2022-11-11

    申请人: CALUSA BIO, LLC

    IPC分类号: C08L89/00

    CPC分类号: C08L89/00

    摘要: The present disclosure relates to the field of polymer chemistry and more particularly to poly(sarcosine) polymers and uses thereof. The disclosure is also directed to compositions comprising a protein and a poly(sarcosine) polymer and uses thereof.