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公开(公告)号：US20240100517A1
公开(公告)日：2024-03-28
申请号：US17935917
申请日：2022-09-27
发明人： HORN-JIUNN SHEEN , PEI-KUEN WEI , YU-JUI FAN , PO-HAN JUAN , YUNG-YU HUANG
CPC分类号： B01L3/5027 , B01L3/50851 , B01L7/52 , C12M1/38 , B01L2300/1827
摘要： The present disclosure provide a detection device of microfluidic polymerase chain reaction (PCR) and a detection system including the same. This all-in-one device and system may be used to detect at least one biological detection chip, so that can amplify gene fragments at the front-end and detect them at the back-end immediately, decreasing the time required for the analysis, enabling real-time, low-cost, and rapid detection of various viruses, such as EBV and COVID-19, without compromising accuracy or sensitivity.
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公开(公告)号：US11441115B2
公开(公告)日：2022-09-13
申请号：US17042301
申请日：2019-03-12
发明人： Taro Nagai , Yoshiki Sawa , Shigeru Miyagawa , Kenji Oyama
摘要： When detachment of a cell sheet from a culture dish has started at an unintended timing, immediately detach the cell sheet from the culture dish while preventing generation of wrinkles and the like in the cell sheet. A cell culture device captures an image of cells in the culture dish, and controls a cooling mechanism and a shaking mechanism based on the image so as to shake the cells while cooling them.
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公开(公告)号：US11193098B2
公开(公告)日：2021-12-07
申请号：US15539978
申请日：2015-12-22
申请人： NANOBIOSYS INC.
发明人： Sung Woo Kim , Jae Young Byun , Eun-Sub Kim , Duck Joong Kim
摘要： A PCR apparatus comprises a PCR heating block having at least two heater units, wherein the at least two heater units are repeatedly disposed on one side of a substrate in a first direction, and each of the at least two heater units has two or more heaters; and a PCR chip having at least two reaction chambers, wherein the at least two reaction chambers are repeatedly formed in the PCR chip, and when the PCR chip is in contact with the PCR heating block, the at least two reaction chambers are arranged to be contacted with the at least two heater units on the PCR heating block, wherein the PCR chip is repeatedly moved in a back-and-forth direction parallel to the first direction and the at least two reaction chambers of the PCR chip is placed to be in contact with the at least two heater units of the PCR heating block.
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公开(公告)号：US20210147771A1
公开(公告)日：2021-05-20
申请号：US17161145
申请日：2021-01-28
申请人： Arctoris Limited
摘要： An apparatus for controlling an experimental temperature of experimental material is disclosed. The apparatus can include a structural holder structured to hold the experimental material, the structural holder including a surface to receive the experimental material. The apparatus can also include a first layer, a second layer and a third layer of respectively a phase change material, a reflective material and an insulating material, the first layer disposed on the surface of the structural holder, the second layer disposed on the first layer, and the third layer disposed on the second layer, at least the first layer of the phase change material being configured to control the experimental temperature of the experimental material when held by the structural holder.
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公开(公告)号：US10850282B2
公开(公告)日：2020-12-01
申请号：US15327300
申请日：2015-06-22
申请人： NANOBIOSYS INC.
发明人： Sung Woo Kim , Duck Joong Kim , Seung Hyun Jeun
摘要： According to one embodiment of the present invention, a multiplex PCR device is disclosed. The multiplex PCR device comprises a multiplex PCR chip simultaneously carrying a plurality of mutually different nucleic acid molecules, and the invention may be characterised in that, attached spaced apart from each other on the multiplex PCR chip, there are a plurality of probes used for hybridization reactions whereby hybridization takes place specifically with mutually different amplified sequences of the nucleic acid molecules.
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公开(公告)号：US20200332238A1
公开(公告)日：2020-10-22
申请号：US16525958
申请日：2019-07-30
发明人： Shuang GAO , Xin JIN , Juan WANG , Yufei ZHAO , Yuqin TAN , Zhisheng LI , Dehua CHANG
摘要： The present disclosure provides a culture device and a preparation method for a cell membrane, and relates to the field of cell culture technology. The culture device for a cell membrane includes a semiconductor refrigerator, and one or more culture vessels configured to culture a cell membrane. The semiconductor refrigerator includes a first insulating substrate, a second insulating substrate, and at least one semiconductor thermocouple disposed between the first insulating substrate and the second insulating substrate. The one or more culture vessels are disposed on a side of the first insulating substrate away from the second insulating substrate.
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公开(公告)号：US20180265830A1
公开(公告)日：2018-09-20
申请号：US15984770
申请日：2018-05-21
申请人： Alga Pangea GmbH
发明人： Juergen SCHUSTER , Ralf ITTERMANN
CPC分类号： C12M21/02 , C12M1/02 , C12M1/38 , C12M23/18 , C12M23/34 , C12M27/20 , C12M31/08 , C12M31/10 , C12M41/22
摘要： A system for growing and reproducing microorganisms that includes a basin system that includes a number of basins, where each basin has a vertical meandering system which is formed by partitions and which can be illuminated, each basin is filled with a nutrient suspension, at least one outer wall of each basin is double-walled such that a cavity is formed, a temperature control medium for controlling the temperature of the nutrient suspension can flow through the cavity.
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公开(公告)号：US10005996B2
公开(公告)日：2018-06-26
申请号：US15112988
申请日：2015-01-22
IPC分类号： C12Q1/04 , C12M1/36 , C12M1/38 , C12M3/00 , C12M1/34 , C12M1/00 , C12M1/12 , G01N33/52 , B05D1/28
摘要： A device for the culturing and/or isolation and/or detection and/or identification and/or counting of at least one target microorganism in a sample liable to contain it, which includes a support and a nutrient medium; the support including: a hydrophilic fibrous substrate, at least one porous layer in contact with one of the faces of the fibrous substrate, including a pigment or a mixture of pigments and at least one binder, the pigment having a size of less than 5 μm and the amount of the pigment or the mixture of pigments being between 50 and 97% by dry weight, with respect to the dry weight of the porous layer; the nutrient medium being included in the fibrous substrate. Also relates to the use and to the process for the manufacture of the device.
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公开(公告)号：US09926530B2
公开(公告)日：2018-03-27
申请号：US14405965
申请日：2013-04-16
发明人： Dominique Vacher , Jean-Noel Gouze
CPC分类号： C12N5/0626 , B01L7/00 , B01L9/52 , B01L2300/1855 , B01L2300/1877 , C09K5/063 , C12M23/10 , C12M41/12 , C12M45/09 , C12M45/20 , C12N2509/00 , C12N2523/00 , Y02E60/145
摘要： The present invention relates to the use of warmers, or autonomous heat packs, for heating and maintaining a solution on at a suitable temperature, for the period of time required to accomplish a chemical, biochemical or biological reaction, in particular in molecular biology or cell biology applications. Biology kits containing warmers are also part of this invention.
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公开(公告)号：US09907117B2
公开(公告)日：2018-02-27
申请号：US14732049
申请日：2015-06-05
发明人： Chen Su , Hsiao-Fen Chang , Pei-Yu Li , Yun-Lung Tsai , Ching-Ko Lin , Wen-Hao Cheng , Pin-Hsing Chou
CPC分类号： H05B1/0247 , B01L7/52 , C12M1/38 , H05B3/06 , H05B3/22 , H05B3/42 , H05B2203/016
摘要： The present disclosure relates to a heating device and a biochemical reactor having the heating device. The heating device includes an upper plate, a lower plate, a middle plate, and an electric heating element. The upper plate has an upper heating hole, an upper receiving hole, and an upper conductive layer. The lower plate has a lower heating hole, a lower receiving hole, and a first lower conductive layer. The middle plate is disposed between the upper and lower plates and has a middle heating hole and a middle receiving hole. The upper, middle and lower receiving holes are connected together to form a receiving through hole. The electric heating element is disposed in the receiving through hole and has two terminals connected to the upper conductive layer and the lower conductive layer, respectively.
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