-
公开(公告)号：US20220010268A1
公开(公告)日：2022-01-13
申请号：US17293832
申请日：2019-12-26
申请人： Calysta, Inc.
发明人： Renee M. Saville , Joshua A. Silverman , Vincent Tang , Eric G. Luning , Paloma Rueda , Megan Hsi , Yelena Stegantseva
摘要： The present disclosure provides methanotrophic bacteria that are modified to produce less glycogen, and methods of using the modified methanotrophic bacteria to produce a desired product, such as protein(s) or metabolite(s).
-
公开(公告)号：US10941426B2
公开(公告)日：2021-03-09
申请号：US16671020
申请日：2019-10-31
摘要： Embodiments of the invention relate to the microbial production of polyhydroxyalkanoic acids, or polyhydroxyalkanoates (PHA), from substrates which cannot be used as a source of carbon and/or energy for microbial growth or PHA synthesis and which have microbial and environmental toxicity. According to one embodiment of the invention, a process for the production of PHA is provided wherein an enzyme such as methane monooxygenase is used to convert volatile organic compounds into PHA through the use of microorganisms that are unable to use volatile organic compounds as a source of carbon for growth or PHA production.
-
公开(公告)号：US10889842B2
公开(公告)日：2021-01-12
申请号：US14599383
申请日：2015-01-16
申请人： CALYSTA, INC.
发明人： Renee M. Saville , Joshua A. Silverman , Eric G. Luning , Brandon D. Doss , Lorraine Joan Giver , Sol M. Resnick , Drew D. Regitsky
摘要： The present disclosure relates to recombinant microorganisms engineered for enhance production of a desired amino acid, as well as related biomass, and compositions which are useful, inter alia, as animal feed ingredients. The present invention also provides related methods.
-
公开(公告)号：US10724055B2
公开(公告)日：2020-07-28
申请号：US15744666
申请日：2016-07-13
申请人： Synata Bio, Inc.
发明人： Robert Hickey
摘要： The methods are disclosed for sustaining a population of microorganisms in an aqueous fermentation broth used in a process to convert syngas to alcohol when the supply of syngas is impaired. The methods involve supplying at least one formate moiety at a rate and amount sufficient to maintain the population of microorganisms. The introduction of the formate moiety also results in the production of at least one metabolic compound other than ethanol and/or acetate by the microorganisms. The metabolic compound can comprise at least one energy storage compound which can be used to support the microorganisms during processing, storage and reactivation.
-
公开(公告)号：US20200172942A1
公开(公告)日：2020-06-04
申请号：US16671020
申请日：2019-10-31
摘要： Embodiments of the invention relate to the microbial production of polyhydroxyalkanoic acids, or polyhydroxyalkanoates (PHA), from substrates which cannot be used as a source of carbon and/or energy for microbial growth or PHA synthesis and which have microbial and environmental toxicity. According to one embodiment of the invention, a process for the production of PHA is provided wherein an enzyme such as methane monooxygenase is used to convert volatile organic compounds into PHA through the use of microorganisms that are unable to use volatile organic compounds as a source of carbon for growth or PHA production.
-
公开(公告)号：US20190264164A1
公开(公告)日：2019-08-29
申请号：US16405587
申请日：2019-05-07
申请人： Calysta, Inc.
摘要： Reactors, systems and processes for the production of biomass by culturing microorganisms in aqueous liquid culture medium circulating inner loop reactor which utilize nonvertical pressure reduction zones are described. Recovery and processing of the culture microorganisms to obtain products, such as proteins or hydrocarbons is described.
-
7.发明授权Method for producing microbial cells and use thereof to produce oxidation products 失效生产微生物细胞的方法及其生产氧化产物的用途
公开(公告)号：US4375515A
公开(公告)日：1983-03-01
申请号：US215248
申请日：1980-12-11
IPC分类号： C07D301/02 , C07D303/04 , C12N1/16 , C12N1/20 , C12N1/30 , C12N1/32 , C12N9/02 , C12N9/04 , C12P7/02 , C12P7/04 , C12P7/06 , C12P7/26 , C12P7/28 , C12P17/02
CPC分类号： C12N9/0073 , C07D301/02 , C07D303/04 , C12N1/16 , C12N1/20 , C12N1/30 , C12N1/32 , C12N9/0006 , C12P17/02 , C12P7/02 , C12P7/04 , C12P7/06 , C12P7/26 , C12P7/28 , C12Y114/13025 , Y02E50/17 , Y10S435/822 , Y10S435/858
摘要： Disclosed are newly discovered and isolated methylotrophic microorganism strains and their natural and/or artificial mutants which grow well under aerobic conditions in a culture medium in the presence of methane as the major carbon and energy source. The methane-grown microbial cells possess a high content of protein and can be utilized as such as feedstuffs. The methane-grown microbial cells or enzyme preparations thereof are also useful in converting C.sub.1 -C.sub.6 alkanes to alcohols, particularly methane to methanol, C.sub.3 -C.sub.6 alkanes to the corresponding C.sub.3 -C.sub.6 sec. alcohols and methyl ketones, C.sub.3 -C.sub.6 sec. alcohols to the corresponding methyl ketones, cyclic hydrocarbons to cyclic hydrocarbyl alcohols (e.g., cyclohexane to cyclohexanol) C.sub.2 -C.sub.4 alkenes selected from the group consisting of ethylene, propylene, butene-1 and butadiene to 1,2-epoxides, styrene to styrene oxide, and converting other oxidizable substrates to oxidized products. The newly discovered and isolated methylotrophic microorganism strains may be aerobically grown on a plurality of methyl-radical donating carbon-containing compounds, such as methanol, methylamine, methyl formate, methyl carbonate, dimethyl ether, etc., to produce microbial cells or enzyme preparations capable of aerobically converting C.sub.3 -C.sub.6 linear secondary alcohols to the corresponding methyl ketones.
摘要翻译： 公开了新发现和分离的甲基营养性微生物菌株及其天然和/或人工突变体，其在甲烷作为主要碳源和能源的存在下，在有氧条件下在培养基中生长良好。 甲烷生长的微生物细胞具有高含量的蛋白质，可以像饲料一样使用。 甲烷生长的微生物细胞或其酶制剂也可用于将C1-C6烷烃转化为醇，特别是甲烷转化为甲醇，C3-C6烷烃转化为相应的C3-C6秒。 醇和甲基酮，C3-C6秒。 醇与相应的甲基酮，环状烃与环状烃类醇（例如环己烷至环己醇）选自乙烯，丙烯，丁烯-1和丁二烯至1,2-环氧化物的C2-C4烯烃，苯乙烯至苯乙烯氧化物 ，并将其它可氧化底物转化为氧化产物。 新发现和分离的甲基营养微生物菌株可以在多个含甲基供体的含碳化合物如甲醇，甲胺，甲酸甲酯，甲基碳酸酯，二甲醚等上进行有氧生长，以产生微生物细胞或酶制剂 能够有用地将C3-C6直链仲醇转化为相应的甲基酮。
-
公开(公告)号：US4003790A
公开(公告)日：1977-01-18
申请号：US603416
申请日：1975-08-11
摘要： Use of urease positive micro-organisms to form ammonium-ions in a process for the culture of hydrocarbon-utilizing micro-organisms.
摘要翻译： 在利用烃类微生物培养的过程中使用脲酶阳性微生物形成铵离子。
-
公开(公告)号：US3834989A
公开(公告)日：1974-09-10
申请号：US22334872
申请日：1972-02-03
申请人： SHELL OIL CO
发明人： HARRISON D
CPC分类号： C12N1/32 , C12N1/00 , C12N1/30 , C12N1/38 , Y10S435/822 , Y10S435/874
摘要： MICRO-ORGANISMS ARE PRODUCED BY INOCULATING WITH MICRO-ORGANISMS A STERILE LIQUID GROWTH MEDIUM CONTAINING ASSIMILABLE SOURCES OF NITROGEN AND ESSENTIAL MINERAL SALTS, ALLOWING THE MICRO-ORGANISMS TO GROW, AND THEN ADDING FRESH STERILE GROWTH MEDIUM CONTAINING A STERILIZING CONCENTRATION OF A MICROBIOCIDE WHICH, AT THE LOWER CONCENTRATIONS PRODUCED BY ADMIXTURE OF THE FRESH MEDIUM WITH THE INOCULATED MEDIUM, IS METABOLIZABLE BY THE MICRO-ORGANISMS.
-
10.发明授权
公开(公告)号：US3764481A
公开(公告)日：1973-10-09
申请号：US3764481D
申请日：1970-09-04
申请人： MULLER H
发明人： MULLER H
CPC分类号： C12N1/30 , Y10S435/812 , Y10S435/818
摘要： IN FERMENTATION REACTIONS IN WHICH BURNABLE COMPOUNDS ARE USED AS THE SOURCE OF CARBON, THE POSSIBILITY OF EXPLOSION IN PRESENT SINCE OXYGEN-CONTAINING GASES MUST ALSO BE INTRODUCED. EMULSIFICATION OF THE ENTIRE CONTENTS OF THE REACTION VESSEL ELIMINATES THE DANGER OF EXPLOSION WITHIN THE VESSEL. ON LEAVING THE VESSEL, THE EMULSION MAY BE BROKEN EITHER BY MECHANICAL OR CHEMICAL MEANS. AT THIS POINT A GAS WHICH DOES NOT SUPPORT COMBUSTION MAY BE ADDED TO DILUTE THE GASEOUS MIXTURE RELEASED FROM THE EMULSION AND THEREBY ELIMATE THE DANGER OF EXPLOSION EXTERNAL TO THE REACTION VESSEL.
-
-
-
-
-
-
-
-
-
搜索结果
77 条记录 (耗时 0.022 秒)