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公开(公告)号：US12065680B2
公开(公告)日：2024-08-20
申请号：US18157497
申请日：2023-01-20
申请人： Novozymes A/S
CPC分类号： C12N9/54 , C11D3/386 , C12N9/52 , C12Y304/21062
摘要： The present invention relates to novel subtilase variants exhibiting increased stability and preferably on par or improved wash performance. The variants of the invention are suitable for use in e.g. cleaning or detergent compositions, such as laundry detergent compositions and dish wash compositions, including automatic dish wash compositions. The present invention also relates to isolated DNA sequences encoding the variants, expression vectors, host cells, and methods for producing and using the variants of the invention.
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公开(公告)号：US12060497B2
公开(公告)日：2024-08-13
申请号：US16903028
申请日：2020-06-16
发明人： Hongfei Jia , Ping Wang , Liting Zhang , Andreas Buthe , Xueyan Zhao , Songtao Wu , Masahiko Ishii , Minjuan Zhang
IPC分类号： C09D189/00 , A61K47/60 , C08G65/333 , C09D5/02 , C09D5/16 , C09D7/40 , C09D175/16 , C12N9/14 , C12N9/20 , C12N9/26 , C12N9/54 , C12N9/96 , C12N11/06 , C12N11/089
CPC分类号： C09D189/00 , A61K47/60 , C08G65/33337 , C09D5/024 , C09D5/16 , C09D7/40 , C09D175/16 , C12N9/14 , C12N9/20 , C12N9/2408 , C12N9/2411 , C12N9/54 , C12N9/96 , C12N11/06 , C12N11/089 , C08L2203/02 , C08L2205/02
摘要： Bioactive coatings that are stabilized against inactivation by weathering are provided including a base associated with a chemically modified enzyme capable of enzymatically degrading a component of an organic stain, optionally a lipase or a lysozyme, and optionally a first polyoxyethylene present in the base and independent of the enzyme. The coatings are optionally overlayered onto a substrate to form an active coating facilitating the removal of organic stains or bacterial organic material.
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公开(公告)号：US12043853B2
公开(公告)日：2024-07-23
申请号：US17376669
申请日：2021-07-15
申请人： DANISCO US INC
发明人： Andrew Shaw , David A Estell , Eugene S Sadlowski , Hiroshi Oh , Louise Wallace , Ronaldus Wilhelmus Joannes Hommes , Sang-Kyu Lee
CPC分类号： C12N9/54 , C11D1/02 , C11D3/386 , C11D3/38663 , C12Y304/24
摘要： The present invention provides methods and compositions comprising at least one neutral metalloprotease enzyme that has improved storage stability. In some embodiments, the neutral metalloprotease finds use in cleaning and other applications. In some particularly preferred embodiments, the present invention provides methods and compositions comprising neutral metalloprotease(s) obtained from Bacillus sp. In some more particularly preferred embodiments, the neutral metalloprotease is obtained from B. amyloliquefaciens. In still further preferred embodiments, the neutral metalloprotease is a variant of the B. amyloliquefaciens neutral metalloprotease. In yet additional embodiments, the neutral metalloprotease is a homolog of the the B. amyloliquefaciens neutral metalloprotease. The present invention finds particular use in applications including, but not limited to cleaning, bleaching and disinfecting.
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公开(公告)号：US20240101992A1
公开(公告)日：2024-03-28
申请号：US18473416
申请日：2023-09-25
摘要： Engineered, modified, or mutated Bacillus strains that produce keratinases or serine proteases (KerS) that biologically degrade keratin-containing materials, such as feathers; compositions containing these Bacillus strains or the keratinases they produce, and methods for biologically degrading keratin-containing materials using these strains or keratinases.
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公开(公告)号：US20240076579A1
公开(公告)日：2024-03-07
申请号：US18506648
申请日：2023-11-10
申请人： Novozymes A/S
发明人： Peter Kamp Hansen , Esben Peter Friis , Torben Vedel Borchert , Lars Lehmann Hylling Christensen , Jens Erik Nielsen , Maria Berggaard Silow
CPC分类号： C11D3/38618 , C11D3/044 , C11D3/08 , C12N9/54 , C12Y304/21062
摘要： The present invention relates to compositions comprising protease variants suitable for use in cleaning or detergent compositions, such as laundry detergent compositions and dish wash compositions, including automatic dish wash compositions.
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公开(公告)号：US20240043898A1
公开(公告)日：2024-02-08
申请号：US18265998
申请日：2021-12-23
申请人： SAMYANG CORPORATION
发明人： Jin-Ha KIM , Soun Gyu KWON , Eunsoo CHOI , Bu-Soo PARK , Sin Hye AHN
CPC分类号： C12P21/02 , C12N9/485 , C12Y304/15001 , C12N9/54 , C12Y304/21062 , C12N9/63 , C12Y304/22002
摘要： The present invention relates to a yeast extract having a high tripeptide content and a high dry matter content using a yeast cell containing tripeptide and a method for preparing the same.
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公开(公告)号：US20230295595A1
公开(公告)日：2023-09-21
申请号：US18157497
申请日：2023-01-20
申请人： Novozymes A/S
CPC分类号： C12N9/54 , C11D3/386 , C12N9/52 , C12Y304/21062
摘要： The present invention relates to novel subtilase variants exhibiting increased stability and preferably on par or improved wash performance. The variants of the invention are suitable for use in e.g. cleaning or detergent compositions, such as laundry detergent compositions and dish wash compositions, including automatic dish wash compositions. The present invention also relates to isolated DNA sequences encoding the variants, expression vectors, host cells, and methods for producing and using the variants of the invention.
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公开(公告)号：US20230279068A1
公开(公告)日：2023-09-07
申请号：US18074275
申请日：2022-12-02
IPC分类号： C07K14/51 , A61K47/64 , C07K14/78 , A61K47/60 , A61K38/18 , C07K14/47 , C07K14/49 , C07K14/50 , C07K14/575 , C07K14/65 , C07K14/79 , C12N9/12 , C12N9/54 , C12N9/74
CPC分类号： C07K14/51 , A61K38/1875 , A61K47/60 , A61K47/6435 , A61K47/645 , C07K14/47 , C07K14/4721 , C07K14/49 , C07K14/50 , C07K14/575 , C07K14/65 , C07K14/78 , C07K14/79 , C12N9/12 , C12N9/54 , C12N9/6429 , A61K38/00
摘要： The targeted delivery of growth factors, vasoactive peptides and other representative anabolic peptide drugs from different signaling cascades to bone fracture for accelerated healing is disclosed herein.
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公开(公告)号：US20230183669A1
公开(公告)日：2023-06-15
申请号：US18052489
申请日：2022-11-03
申请人： Novozymes A/S
CPC分类号： C12N9/54 , C12Y304/21062 , C11D3/386 , C12Y304/21
摘要： The present invention relates to protease variants and methods for obtaining protease variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
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公开(公告)号：US20230173014A1
公开(公告)日：2023-06-08
申请号：US17997501
申请日：2021-02-09
发明人： Francisca Isabel BRAVO VÁZQUEZ , Raúl LÓPEZ FERNÁNDEZ , Juan María ALCAIDE HIDALGO , María MARGALEF JORNET , Anna MAS CAPDEVILA , Jose María DEL BAS PRIOR , María Eugenia HERNÁNDEZ DE PABLO , María Begoñia MUGUERZA MARQUÍNEZ
IPC分类号： A61K38/01 , C12N9/54 , A23L33/105 , A23L33/18 , A61P9/12
CPC分类号： A61K38/01 , C12N9/54 , A23L33/105 , A23L33/18 , A61P9/12
摘要： The present invention relates to wine lees and derivatives thereof. Likewise, it relates to their use in medicine.
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