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1.发明授权公开(公告)号：US11629369B2
公开(公告)日：2023-04-18
申请号：US16632295
申请日：2018-07-13
申请人： LSEE
发明人： Sébastien Delile , Cyril Torre
IPC分类号： C12Q1/00 , C12Q1/26 , C12Q1/32 , C12Q1/48 , G01N27/327
摘要： Devices, systems, and methods are used for personalized monitoring of changes in metabolism as a function of external parameters such as food or physical exercise. More particularly, the present disclosure relates to electrochemical strips for detecting the amount of biomarker for fat metabolism, in particular, glycerol.
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公开(公告)号：US20230097988A1
公开(公告)日：2023-03-30
申请号：US17802328
申请日：2021-02-25
发明人： Andreas BERGMANN
IPC分类号： C12Q1/26 , G01N33/574 , G01N33/68
摘要： The present invention is directed to a method for diagnosis or prognosis of a disease in a subject and/or predicting a risk of getting a disease or adverse event in a subject and/or monitoring a disease or adverse event in a subject by determining the level of peptidylglycine alpha-amidating monooxygenase (PAM) and/or its isoforms and/or fragments thereof in a sample of bodily fluid of said subject.
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公开(公告)号：US20230043193A1
公开(公告)日：2023-02-09
申请号：US17867792
申请日：2022-07-19
发明人： Gareth Ackland
摘要： The present invention relates to the detection or diagnosis of infection or inflammation in a patient. In particular, the invention provides methods that allow the detection of markers in a sample from a patient or subject, such as a blood sample, which will indicate whether the patient or subject has an infection or has an inflammatory response.
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公开(公告)号：US20220389475A1
公开(公告)日：2022-12-08
申请号：US17818912
申请日：2022-08-10
IPC分类号： C12Q1/00 , C12Q1/26 , G01N27/327 , C12N11/082 , G01N33/573 , G01N33/66
摘要： NADP-dependent oxidoreductase compositions, and electrodes, sensors and systems that include the same. Analyte sensors include an electrode having a sensing layer disposed thereon, the sensing layer comprising a polymer and an enzyme composition distributed therein. The enzyme composition includes nicotinamide adenine dinucleotide phosphate (NAD(P)+) or derivative thereof; an NAD(P)+-dependent dehydrogenase; an NAD(P)H oxidoreductase; and an electron transfer agent comprising a transition metal complex.
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5.发明授权公开(公告)号：US11513109B2
公开(公告)日：2022-11-29
申请号：US16016606
申请日：2018-06-24
申请人： NANJING UNIVERSITY
发明人： Jinju Geng , Yingying Fu , Xingsheng Gao , Hongqiang Ren
摘要： A biological toxicity test method for evaluating an ecological safety of an advanced oxidation process comprising the following steps: (1) collecting (preparing) a waste water to be determined; (2) collecting the waste water and a tap water after the advanced oxidation process treatment; (3) subjecting Koi (Cyprinus carpio haematopterus) to the water after treatment for exposure to poison; (4) Determining an anti-oxidation enzyme activity of a liver of the Koi after exposure; (5) Data analyzing. By comparing the changes of liver enzyme activities in different water, the present method evaluates the toxicity changes of micro-pollutant containing water before and after treatment, which fills in the gap of the ecological risk assessment for advanced oxidation technology.
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公开(公告)号：US20220333154A1
公开(公告)日：2022-10-20
申请号：US17858628
申请日：2022-07-06
摘要： Glucose sensors comprising a mutated biomolecule immobilised to a substrate are disclosed. The biomolecule is glucose oxidase, concanavalin A, or glucose binding protein. The mutated biomolecule is immobilised to the substrate via a linker comprising a thiol reactive group and a substrate adherence group. The biomolecule is mutated to introduce one or more surface accessible thiol moieties. The mutated biomolecule is connected to the linker via the one or more surface accessible thiol moieties on the biomolecule and the thiol reactive group on the linker.
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公开(公告)号：US20220333153A1
公开(公告)日：2022-10-20
申请号：US17732296
申请日：2022-04-28
发明人： Zhong GUO , Kirill ALEXANDROV
摘要： The invention relates to biosensors. More particularly, this invention relates to an electrochemical biosensor and to electrochemically active enzymes or variants thereof that are suitable for detection of one or more target molecules in a sample.
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公开(公告)号：US20220333150A1
公开(公告)日：2022-10-20
申请号：US17764665
申请日：2020-09-01
发明人： Kiyoto Nakamura , Hirokazu Sanpei
摘要： A biosensor includes: a flow channel through which a liquid sample flows, the liquid sample containing a specific component; a holding sheet that is disposed in the flow channel and holds a substance corresponding to the specific component; and a first temperature sensor that is disposed to correspond to the holding sheet and detects a reaction heat generated by a contact reaction between the specific component and the corresponding substance. The biosensor acquires information on the specific component based on the reaction heat.
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公开(公告)号：US20220323311A1
公开(公告)日：2022-10-13
申请号：US17472971
申请日：2021-09-13
申请人： Georgia Crawford
发明人： Georgia Crawford
摘要： A personal hygiene wipe with an integral urine glucose detection feature. The wipe includes a substrate that is adapted for impregnation with a composition having one or more drying, cleaning, odor control, or antibacterial properties. The wipe also is saturated with a chemical composition for detecting glucose in urine. When glucose is detected, the wipe turns to a different color.
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公开(公告)号：US20220315979A1
公开(公告)日：2022-10-06
申请号：US17620343
申请日：2020-06-16
摘要： Sensors comprising B-L-S; wherein: B is a biomolecule comprising one or more surface-exposed thiol moieties, L is a thiol reactive linking group, and S is a substrate; wherein L is covalently linked to B via the one or more surface-exposed thiol moieties.
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