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公开(公告)号:US08389527B2
公开(公告)日:2013-03-05
申请号:US12866365
申请日:2009-02-06
申请人: Brian E. Fink , Soong-Hoon Kim , Yufen Zhao , Ping Chen , Wayne Vaccaro , Litai Zhang , Ashvinikumar V Gavai , Dharmpal S Dodd , Libing Chen
发明人: Brian E. Fink , Soong-Hoon Kim , Yufen Zhao , Ping Chen , Wayne Vaccaro , Litai Zhang , Ashvinikumar V Gavai , Dharmpal S Dodd , Libing Chen
IPC分类号: A01N43/58 , A01N43/60 , C61K31/50 , C07D487/00
CPC分类号: C07D487/04
摘要: The invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I imidazopyridazines inhibit protein kinase activity thereby making them useful as anticancer agents.
摘要翻译: 本发明提供式I化合物及其药学上可接受的盐。 式I咪唑并哒嗪抑制蛋白激酶活性,从而使其成为抗癌剂。