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    Kit for preparing sample for detecting monoclonal antibody
    1.
    发明授权
    Kit for preparing sample for detecting monoclonal antibody 有权

    公开(公告)号：US12216126B2

    公开(公告)日：2025-02-04

    申请号：US17455089

    申请日：2021-11-16

    Applicant: SHIMADZU CORPORATION

    Inventor： Takashi Shimada ,  Noriko Iwamoto

    IPC: G01N33/68 ,  C12N11/02 ,  C12Q1/00 ,  C12Q1/37 ,  G01N1/10 ,  G01N30/06 ,  G01N30/72 ,  G01N33/577

    Abstract: A sample preparation kit related to the present invention provides a significantly versatile analytical technique that is not affected by the diversity of antibodies, difference in species, matrix and the like. For preparing a sample to be used for detection of a monoclonal antibody through high-performance liquid chromatography-mass spectrometry (LC-MS), the kit includes a porous body for immobilizing a monoclonal antibody to be detected; nanoparticles with an immobilized protease; a reaction vessel for selectively digesting the monoclonal antibody by bringing the porous body and nanoparticles into contact; a buffer to be introduced into the reaction vessel along with the nanoparticles and porous body so that a protease reaction is carried out; and a filtration membrane to remove the porous body and nanoparticles after the proteolysis so as to extract the reaction product and the buffer.

    DEVICE FOR COLLECTING BIOLOGICAL SAMPLES
    3.
    发明申请
    DEVICE FOR COLLECTING BIOLOGICAL SAMPLES 有权

    公开(公告)号：US20250012677A1

    公开(公告)日：2025-01-09

    申请号：US18704641

    申请日：2022-10-26

    Applicant: BIC Violex Single Member S.A. ,  SOCIÉTÉ BIC

    Inventor： Georgios KATSIKAS ,  Panagiotis KOPELAS ,  Efthymios SALTAS ,  Etienne MICHENAUD

    IPC: G01N1/10

    Abstract: The present disclosure relates to a device for collecting one or more biological samples comprising a housing and a collector element, wherein the collector element allows the passage of liquid, and wherein the collector element extends between a first end and a second end, the first end of the collector element protruding out of the housing for collecting the one or more biological samples, the second end of the collector element being arranged within the housing. The device further comprises a fixation element for engaging the second end of the collector element, wherein the fixation element has at least two parts which can be moved relative to one another for engaging the second end of the collector element, and wherein the housing comprises a connector element having an internal shape which is designed to maintain the parts of the fixation element in their engaged position.

    Displaceable receptacle for test sample
    4.
    发明授权
    Displaceable receptacle for test sample 有权

    公开(公告)号：US12158420B2

    公开(公告)日：2024-12-03

    申请号：US17841003

    申请日：2022-06-15

    Applicant: Specac Limited

    Inventor： Michael Ramsay ,  George Harman ,  Ian Gaskin

    IPC: G01N21/552 ,  G01N1/10 ,  G01N1/14 ,  G01N21/03

    Abstract: A system for containing a sample for analysis by a spectrometer, comprising a sample receptacle unit with a well for containment of the sample, the well comprising a well inner wall and well floor, a floor aperture in the well floor, and comprising a first spectroscopy element, the first spectroscopy element spanning the opening of floor aperture, wherein the well further comprises a sealing material at the interface of the inner wall with the first spectroscopy element, wherein radiation is free to pass through the floor aperture to the first spectroscopy element.

    Portable inspection, collection, and delivery apparatus for fluid-based systems
    6.
    发明授权
    Portable inspection, collection, and delivery apparatus for fluid-based systems 有权

    公开(公告)号：US12146837B2

    公开(公告)日：2024-11-19

    申请号：US17805488

    申请日：2022-06-06

    Applicant: International Business Machines Corporation

    Inventor： Madhana Sunder ,  Mary Ann Zaitz ,  Joyce E. Molinelli Acocella ,  Michael J. Ellsworth, Jr.

    IPC: G01N21/88 ,  G01N1/10

    Abstract: An apparatus used for analysis of a fluid-based system that includes a main chamber consisting of an optically transparent high strength material that ensures transmission of infrared and ultraviolet wavelengths and is capable of withstanding high pressures. The apparatus also includes first and second fluid tight endcaps attached to first and second ends of the main chamber, wherein the first endcap permits entry of a fluid into the main chamber and the second endcap permits the fluid to exit the main chamber. The apparatus further includes a fixed filter guide rail located inside the main chamber and attached to one of the end caps, and a filter located inside the main chamber and configured to removably attach to the fixed filter guide rail, wherein the filter is capable of capturing residue or contaminants in the fluid.

    SAMPLE COLLECTION DEVICE AND SAMPLE COLLECTION METHOD
    7.
    发明公开
    SAMPLE COLLECTION DEVICE AND SAMPLE COLLECTION METHOD 审中-公开

    公开(公告)号：US20240361209A1

    公开(公告)日：2024-10-31

    申请号：US18685336

    申请日：2022-08-17

    Applicant: SEEGENE, INC.

    Inventor： Won Sik Sik KIM ,  Kyoung Min Sik ROH ,  Myung Jun Sik SEO ,  Young II Sik UM

    IPC: G01N1/12 ,  G01N1/10

    CPC classification number: G01N1/12 ,  G01N2001/1056

    Abstract: The present invention relates to a sample collection device, comprising: (a) a first tube accommodating a sample; wherein the first tube comprises an opened end part; (b) a second tube accommodating a sample transport medium; wherein the second tube comprises an opened end part; and (c) an adapter; wherein the adapter comprises a first accommodating part formed such that the opened end part of the first tube is inserted, a second accommodating part formed to be coupled to the opened end part of the second tube and a sealing part that comprises a first surface facing the first accommodating part and a second surface facing the second accommodating part, and partitions the first accommodating part and the second accommodating part, and wherein a breaking line is formed on the sealing part such that the sealing part is broken by a contact pressure.

    Portable system for analyzing microbial population in a fluid
    9.
    发明授权
    Portable system for analyzing microbial population in a fluid 有权

    公开(公告)号：US12066422B2

    公开(公告)日：2024-08-20

    申请号：US17288772

    申请日：2019-12-13

    Applicant: LUMINULTRA TECHNOLOGIES LTD.

    Inventor： Patrick Andrew Whalen ,  Derek Christopher Dunn ,  William Dicke ,  Xavier Boulerice ,  David McMullin ,  Michael Brown

    IPC: G01N33/18 ,  G01N1/10 ,  G01N21/76

    CPC classification number: G01N33/18 ,  G01N1/10 ,  G01N21/76

    Abstract: A system and process may be used to test water samples to measure ATP and/or estimate a microbial population, for example using an adenosine triphosphate (ATP) based assay. The system includes a device that is use in combination with single-use or disposable cartridges. The cartridge receives the water sample and is pre-loaded with one or more reagents. The device receives the cartridge and contains physical, electronic and/or mechatronic devices that interact with cartridge. One or more actions such as metering, mixing and conveying are performed automatically by elements of the device and/or cartridge. A sensor in the device measures light produced in the cartridge from a reaction with ATP in the water sample. Optionally, the cartridge also contains a pre-loaded amount of ATP, which is used to provide an internal reference or calibration measurement.

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