公开(公告)号：US12208187B2

公开(公告)日：2025-01-28

申请号：US18514916

申请日：2023-11-20

Applicant: Fresenius Medical Care Holdings, Inc. ,  Fresenius Medical Care Deutschland GmbH

Inventor： Martin Joseph Crnkovich ,  Colin Weaver ,  Christian Schlaeper

IPC: A61M1/16 ,  G01N27/06

Abstract: In some embodiments, a medical system includes a dialysis machine having at least one outer surface to be disinfected at a given location, at least one disinfection sensor connected to the dialysis machine at the given location, the disinfection sensor including two or more electrode in fluid contact with the outside surface of the dialysis machine, and a conductivity sensor component in electrical contact with the two or more electrodes, the conductivity sensor component configured to send an electrical signal indicating a conductivity of a liquid on an outside surface of the dialysis machine and in contact with the two or more electrodes, a processor configured to receive the electrical signal and thereby determine a disinfection status of the given location, and a user interface configured to indicate the disinfection status of the given location.

公开(公告)号：US20240410848A1

公开(公告)日：2024-12-12

申请号：US18329907

申请日：2023-06-06

Applicant: Cypress Semiconductor Corporation

Inventor： Volodymyr BIHDAY ,  Yaroslav BERKO ,  Igor KRAVETS ,  Mykhaylo KREKHOVETSKYY ,  VasyI MANDZIY ,  Marian MULIARCHYK ,  Andrii Tsemko

IPC: G01N27/04 ,  G01N27/06

Abstract: One or more computing devices, systems, and/or methods are provided. In an example, a method comprises measuring a first charge generated by a first excitation signal and transferred during a first time interval to a first electrode mounted to a container holding a test fluid, measuring a second charge generated by a second excitation signal and transferred during a second time interval to the first electrode, and determining a parameter of the test fluid based on a first charge transfer curve generated based on the first charge and the second charge.

公开(公告)号：US20240399036A1

公开(公告)日：2024-12-05

申请号：US18700276

申请日：2022-10-11

Applicant: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH

Inventor： Andreas MAIERHOFER

IPC: A61M1/16 ,  A61M1/34 ,  G01N27/06 ,  G01N33/487

Abstract: The invention relates to a method and a device for monitoring blood purification with an extracorporeal blood purification device which is designed such that a blood purification unit 1 is used to perform blood purification with predetermined treatment parameters Qb in an extracorporeal blood circuit 9. The concentration of a substance is measured during the blood purification with at least one sensor 31, 32, 33, 34 and a parameter K which is characteristic of the purifying performance of the blood purification unit 1 is determined with a computing and/or evaluation unit 25 on the basis of the measured concentration of a substance. The parameter K which is characteristic of the purifying performance of the blood purification unit 1 is compared with an expected value Kref. To this end, a tolerance range is determined for the expected value using the computing and/or evaluation unit 25, wherein actions that are predetermined by the computing and/or evaluation unit 25 are triggered depending on whether the parameter which is characteristic of the purifying performance of the blood purification unit lies within or outside the tolerance range for the expected value.

公开(公告)号：US12123817B2

公开(公告)日：2024-10-22

申请号：US18234047

申请日：2023-08-15

Applicant: The Government of the United States of America, as represented by the Secretary of Homeland Security

Inventor： Jeffrey Barber ,  James C. Weatherall ,  Duane Karns ,  Barry T. Smith

IPC: G01N11/00 ,  G01N21/45 ,  G01N27/06

CPC classification number: G01N11/00 ,  G01N21/45 ,  G01N27/06

Abstract: A device to determine density includes a housing, a first transducer disposed in the housing at a first position, and a second transducer disposed in the housing at a second position. The second transducer is located a distance from the first transducer. The device also includes a controller that reads a first output from the first transducer, and reads a second output from the second transducer. The controller determines a density of a liquid based on the first output, the second output, and the distance.

公开(公告)号：US12105041B2

公开(公告)日：2024-10-01

申请号：US17974832

申请日：2022-10-27

Applicant: UIF (University Industry Foundation), Yonsei University

Inventor： Cheol Min Park ,  Jeongok Park ,  Seung Won Lee ,  Ji Hye Jang ,  Hye Jin Kim ,  Kyoung Jin Lee

IPC: G01N27/06 ,  G01N27/07 ,  G01N27/14 ,  G01N27/22

CPC classification number: G01N27/07 ,  G01N27/14 ,  G01N27/226 ,  G01N2201/1211 ,  G01N2201/1218

Abstract: A detection device includes a substrate, first electrodes formed on a first surface of the substrate, a responsive layer, and second electrodes formed on a first surface of the responsive layer, each of the second electrodes are capacitively coupled to one of the first electrodes and each second electrode is connected to a power supply to provide driving power.

公开(公告)号：US11994484B2

公开(公告)日：2024-05-28

申请号：US17703783

申请日：2022-03-24

Applicant: The Regents of the University of California

Inventor： Kevin Freedman ,  Vinay Sharma

IPC: G01N27/06 ,  G01N27/447 ,  G01N33/487 ,  G01N11/04

CPC classification number: G01N27/06 ,  G01N33/48728 ,  G01N11/04 ,  G01N27/447

Abstract: A method includes providing a fluid to a structure including an aperture, applying a voltage signal to a circuit that includes the fluid, applying a substantially periodic pressure signal to the fluid, detecting a current signal in the circuit as an analyte passes through the aperture in response to the substantially periodic pressure signal, and processing the current signal and the substantially periodic pressure signal to determine a switch time and a release time for the analyte. An apparatus includes a structure including an aperture to receive a fluid, a voltage source to provide a voltage signal to an electronic circuit having a path that includes the aperture, a pressure signal generator to provide a substantially periodic pressure signal to the fluid, and a system to process the periodic pressure signal and a current signal induced in the electronic circuit.

公开(公告)号：US20240167068A1

公开(公告)日：2024-05-23

申请号：US18569372

申请日：2022-06-30

Applicant: eTheRNA immunotherapies NV

Inventor： Senne DILLEN ,  Lore DE BRUYNE ,  Michiel HOLTOF

IPC: C12P19/34 ,  C12N9/12 ,  G01N21/59 ,  G01N27/06

CPC classification number: C12P19/34 ,  C12N9/1252 ,  G01N21/59 ,  G01N27/06

Abstract: The present invention relates to the field of nucleic acid production, in particular in vitro RNA transcription. More specifically, the present invention relates to a method wherein physicochemical properties of the reaction mixture are monitored in order to timely stop the reaction and/or to add fresh reagents to allow the reaction to continue under optimal conditions. In particular, conductivity, but also pH and/or optical density is determined at at least two different time points, or continuously during the in vitro transcription reaction.

公开(公告)号：US11977041B2

公开(公告)日：2024-05-07

申请号：US17385145

申请日：2021-07-26

Applicant: Saudi Arabian Oil Company

Inventor： Khaled F. Almarri ,  Hassan M. Alzain

IPC: G01N27/06 ,  G01F23/00 ,  G01N1/14 ,  G01N33/28 ,  G01R31/382

CPC classification number: G01N27/06 ,  G01N1/14 ,  G01N33/28 ,  G01F23/00 ,  G01R31/382

Abstract: Systems, methods, and a machine readable medium for measuring conductivity in a hydrocarbon sample are provided. An example conductivity analyzer includes a peristaltic pump to flow the hydrocarbons over a temperature controller and a conductivity probe. The temperature controller includes a Peltier block. The conductivity analyzer also includes the conductivity probe.

公开(公告)号：US11921073B2

公开(公告)日：2024-03-05

申请号：US17710452

申请日：2022-03-31

Applicant: Meas France

Inventor： Fabien Gayrard ,  Antoine Sirven ,  Vincent Ducere

IPC: G01N27/06 ,  G01N27/02 ,  G01N27/07 ,  G01N29/02

CPC classification number: G01N27/07 ,  G01N27/026 ,  G01N29/022

Abstract: A fluid sensor includes a tuning fork mechanical resonator including a base and a tine projecting from the base along a longitudinal direction of the tine, and a pair of electrodes disposed on the tine. The base and the tine are formed from a piezoelectric material including lithium tantalate. The electrodes are exposed to a fluid.

公开(公告)号：US20230349960A1

公开(公告)日：2023-11-02

申请号：US18213450

申请日：2023-06-23

Applicant: Philip SALKIE

Inventor： Philip SALKIE

IPC: G01R27/02 ,  G01N27/06 ,  G01N27/07

CPC classification number: G01R27/02 ,  G01N27/06 ,  G01N27/07

Abstract: In some embodiments, the conductivity measurement device includes a conductivity probe, a solid state switch device, and a DC measurement circuit. The conductivity probe includes a first and second measurement pin used to measure a conductivity of the liquid. The solid state switch device is coupled to the conductivity probe and is configured to connect and disconnect the first measurement pin and second measurement pin to a first DC reference voltage and a second DC reference voltage. The DC measurement circuit is configured to generate a measurement signal such that the measurement signal is maintained at a first DC reference voltage and the first DC reference voltage is applied to the solid state switch device from the DC measurement circuit. In this manner, an alternating current (AC) voltage is applied to the measurement pins utilizing DC reference voltages, which helps to avoid contamination of the liquid.