公开(公告)号：US20250040829A1

公开(公告)日：2025-02-06

申请号：US18238276

申请日：2023-08-25

Applicant: UltraE Co. Ltd.

Inventor： Hsieh-Hsun Chung ,  Ping-Hsi Hsieh

IPC: A61B5/08 ,  A61B5/097 ,  G01N27/30

Abstract: A method for detecting Helicobacter pylori using an electrochemical test strip, comprising the following steps: making a subject to exhale a first gas sample into a detection zone of an electrochemical test strip via a blowpipe, using the electrochemical test strip to detect the first gas sample to obtain a background pH data; the subject is allowed to consume urea; making the subject to exhale a second gas sample into the detection zone of another/the electrochemical test strip via the blowpipe, using the electrochemical test strip to detect the second gas sample to obtain a desired pH data; comparing the background pH data and the desired pH data to determine whether the subject's stomach is infected with Helicobacter pylori.

公开(公告)号：US20250035578A1

公开(公告)日：2025-01-30

申请号：US18782972

申请日：2024-07-24

Applicant: Sergio Garcia-Segura ,  Rishabh Bansal ,  Vanessa Hald

Inventor： Sergio Garcia-Segura ,  Rishabh Bansal ,  Vanessa Hald

IPC: G01N27/30 ,  G01N27/48

Abstract: A composite electrode includes a polypyrrole matrix, and metal nanoparticles coupled to the polypyrrole matrix. Assessing the presence of an analyte includes placing the composite electrode in a solution to be tested for the analyte, applying an electrical current to the electrode, and assessing the presence of an oxidation peak at a predetermined voltage with respect to a reference electrode. The presence of the oxidation peak at the predetermined voltage indicates the presence of the analyte. Fabricating the composite electrode includes electropolymerizing a polypyrrole matrix onto a metal substrate, separating the polypyrrole matrix from the metal substrate, and electrodepositing the metal nanoparticles onto the polypyrrole matrix to yield the electrode.

公开(公告)号：US12196749B2

公开(公告)日：2025-01-14

申请号：US16942130

申请日：2020-07-29

Applicant: Meso Scale Technologies, LLC.

Inventor： Eli N. Glezer ,  Jonathan K. Leland ,  Mark A. Billadeau ,  Joseph M. Leginus ,  Bandele Jeffrey-Coker ,  Jeff D. Debad ,  Koustubh A. Phalnikar ,  Sriram Jambunathan

IPC: G01N33/543 ,  B01J19/00 ,  B01L3/00 ,  B01L9/00 ,  C12Q1/00 ,  G01N21/76 ,  G01N27/30 ,  B33Y80/00 ,  C40B40/10

Abstract: Assay modules, preferably assay cartridges, are described as are reader apparatuses which may be used to control aspects of module operation. The modules preferably comprise a detection chamber with integrated electrodes that may be used for carrying out electrode induced luminescence measurements. Methods are described for immobilizing assay reagents in a controlled fashion on these electrodes and other surfaces. Assay modules and cartridges are also described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain preferred embodiments, these modules are adapted to receive and analyze a sample collected on an applicator stick.

公开(公告)号：US20250012773A1

公开(公告)日：2025-01-09

申请号：US18709246

申请日：2022-11-11

Applicant: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS

Inventor： Wenchao DUAN ,  Martí GICH GARCíA ,  César FERNÁNDEZ SÁNCHEZ

IPC: G01N33/18 ,  G01N27/30 ,  G01N27/48

Abstract: The present invention relates to a screen-printed electrode (1) for detecting a pollutant in a water sample, comprising: a substrate (2); a plurality of conductive tracks (3); an electrochemical cell (4), further comprising a working electrode (5), a pseudo-reference electrode (6) and an auxiliary electrode (7); and an insulating layer (8). Advantageously, said electrode comprises a filtering element (9) impregnated with an electrolyte, which not only filters the water sample received by the electrochemical cell (4), but also preconditions the sample without any user intervention. Therefore, the screen-printed electrode of the invention saves time in pre-processing samples for water pollution analysis while avoiding any possible contamination thereof by user manipulation.

公开(公告)号：US20250003917A1

公开(公告)日：2025-01-02

申请号：US18738839

申请日：2024-06-10

Applicant: CANON MEDICAL SYSTEMS CORPORATION ,  Nanjing University

Inventor： Xiaotian WU ,  Qiqi XU ,  Hao HUANG ,  Huangxian JU ,  Jie WU

IPC: G01N27/30 ,  C12Q1/6825 ,  C12Q1/70 ,  G01N27/327

Abstract: A method for producing an electrochemiluminescence nanoprobe according to an embodiment includes: a Pdots nanoparticle synthesis step of synthesizing a Pdots nanoparticle by polymerizing a conjugated polymer and a copolymer molecule; and a Pdots nanoparticle modification step of modifying a resulting Pdots nanoparticle using an oligonucleotide chain modified with a quencher molecule.

公开(公告)号：US12159998B2

公开(公告)日：2024-12-03

申请号：US17434540

申请日：2020-02-25

Applicant: NITTO DENKO CORPORATION ,  National Institute of Advanced Industrial Science and Technology

Inventor： Motoki Haishi ,  Mitsunobu Takemoto ,  Tatsuya Kitahara ,  Kentaro Takeda ,  Dai Kato ,  Tomoyuki Kamata

IPC: G01N27/30 ,  H01M4/583

Abstract: A carbon electrode includes a substrate, and a conductive carbon layer disposed at an upper side of the substrate and having an sp2 bond and an sp3 bond. On an upper surface of the conductive carbon layer, the concentration ratio of oxygen to carbon is 0.07 or more. The ratio of a number of sp3 bonded carbon atoms to the sum of a number of sp2 bonded carbon atoms and the number of sp3 bonded carbon atoms is 0.35 or more.

公开(公告)号：US20240393305A1

公开(公告)日：2024-11-28

申请号：US18666900

申请日：2024-05-17

Applicant: The Penn State Research Foundation

Inventor： Huanyu Cheng

IPC: G01N33/00 ,  G01K1/024 ,  G01N27/30

Abstract: An apparatus including at least one vanadium oxide-doped laser-induced graphene sensor is disclosed. The sensor is configured to simultaneously monitor and decouple NOX gas emission and soil temperature. The apparatus may be an electronic device including a plurality of electrical components, such as a controller unit that is connected to non-transitory memory or other type of non-transitory computer readable medium and a transceiver unit.

公开(公告)号：US20240377349A1

公开(公告)日：2024-11-14

申请号：US18692747

申请日：2022-09-16

Applicant: The Regents of the University of California

Inventor： Payton Goodrich ,  Ana Claudia Arias ,  Carol Baumbauer ,  Margaret E. Payne ,  Anju Toor

IPC: G01N27/403 ,  G01N27/30 ,  G01N27/333

Abstract: An example apparatus is disclosed. The apparatus includes a reference electrode and an ion selective electrode (ISE). The reference electrode includes a reference electrode substrate, a reference electrode conductor formed via a printable composition on the reference electrode substrate, and a reference membrane formed on the carbon nanotube layer. The ISE includes an ISE substrate, a ISE conductor printed on the substrate via a printable composition on the ISE substrate, and an ion-selective membrane printed on the conductor via a printable membrane solution.

公开(公告)号：US12138050B2

公开(公告)日：2024-11-12

申请号：US18460271

申请日：2023-09-01

Applicant: Medtronic, Inc.

Inventor： Daniel Hahn ,  Mohsen Askarinya ,  James K. Carney ,  Patrick W. Kinzie ,  Jennifer Lorenz Marckmann ,  Randal C. Schulhauser ,  Santhisagar Vaddiraju ,  Akhil Srinivasan ,  David Probst ,  Alejo Chavez Gaxiola

IPC: A61B5/1468 ,  A61B5/053 ,  A61B5/145 ,  A61B5/1486 ,  G01N27/30 ,  G01N27/327

Abstract: A biocompatible medical device may include an electrochemical sensor including a common reference electrode; at least one counter electrode; and a work electrode platform comprising a plurality of respective work electrodes, each respective work electrode electrically coupled to the common reference electrode and comprising a respective reagent substrate configured to react with a respective analyte to produce a respective signal indicative of a concentration of the respective analyte; and processing circuitry operatively coupled to the electrochemical sensor, and configured to receive from the electrochemical sensor a plurality of signals from the plurality of respective work electrodes; identify the respective signal corresponding to a respective selected work electrode; and process the identified signal to determine the concentration of the respective analyte associated with the respective selected work electrode.

公开(公告)号：US20240360000A1

公开(公告)日：2024-10-31

申请号：US18037559

申请日：2022-06-29

Applicant: SOOCHOW UNIVERSITY

Inventor： Yanyan WANG

IPC: C01G51/00 ,  C01B32/225 ,  C01B32/23 ,  C01G51/04 ,  G01N27/30

CPC classification number: C01G51/30 ,  C01B32/225 ,  C01B32/23 ,  C01G51/04 ,  G01N27/30 ,  C01P2004/03 ,  C01P2004/80

Abstract: A method for preparing a cobalt sulfide/reduced graphite oxide composite includes: preparing a glycerol-cobalt precursor by taking a water-soluble cobalt salt, a micromolecular alcohol solvent, and glycerol as raw materials; mixing the glycerol-cobalt precursor with an alkali liquor to prepare a Co(OH)2 nanoflower; calcining the Co(OH)2 nanoflower to obtain a Co3O4 nanoflower; subjecting the Co3O4 nanoflower to a reaction with a water-soluble sulfur salt to obtain a COS nanoflower, and mixing the COS nanoflower with graphite oxide and carrying out a heat treatment to obtain the composite. The response characteristics of a gas sensor to NO2 gas are studied at room temperature, and the graphite is complexed with a transition metal sulfide with unique morphology to construct a unique heterostructure. While expanding the specific surface area to increase the number of adsorption sites, the heterostructure of a contact surface is used to greatly enhance the charge-transfer efficiency.