公开(公告)号：US11204345B2

公开(公告)日：2021-12-21

申请号：US16250399

申请日：2019-01-17

申请人： Yamazen Corporation

发明人： Kihachiro Okura

IPC分类号： B01D15/10 ,  G01N30/91 ,  G01N30/92 ,  G01N30/94 ,  G01N30/95

摘要： To provide a preparative thin layer chromatography method capable of acquiring a target spot efficiently using a simple and convenient method without the possibility of decomposition of a component in a spot. The preparative thin layer chromatography method is a preparative method for dispensing a spot from a thin layer chromatography plate and includes a process 1 that forms a groove by removing the carrier at the circumferential edge of a spot to be dispensed, a process 2 that inserts a nozzle having a packing part at the tip thereof into the groove formed in the process 1, a process 3 that discharges a solvent through the nozzle, and a process 4 that sucks the solvent in which a spot component has been dissolved.

公开(公告)号：US10908152B2

公开(公告)日：2021-02-02

申请号：US15215107

申请日：2016-07-20

申请人： The Administrators of The Tulane Educational Fund

发明人： Sergey S. Shevkoplyas ,  Xiaoxi Yang ,  Julie Kanter Washko ,  Nathaniel Zane Piety

IPC分类号： G01N30/90 ,  G01N33/52 ,  G01N33/80 ,  G01N30/92 ,  G01N33/66 ,  G01N33/86

摘要： The present invention relates to simple, low-cost, rapid paper-based diagnostic devices and their methods of use.

公开(公告)号：US20190170713A1

公开(公告)日：2019-06-06

申请号：US16321200

申请日：2017-12-06

申请人： Panasonic Intellectual Property Management Co., Ltd.

发明人： TOSHIHIRO SAKAMOTO ,  TOSHINOBU MATSUNO

IPC分类号： G01N30/92 ,  G01N30/91 ,  G01N30/94

摘要： The thin layer chromatography plate includes a substrate and a separation layer. The separation layer is disposed on the substrate and is configured to separate multiple components included in a sample from each other. The separation layer includes a first layer and a second layer. The first layer has a porous structure and extends in a first direction. The second layer has a porous structure and extends in the first direction. The first layer and the second layer are arrayed in a second direction orthogonal to the first direction. A zeta potential of the first layer is different from a zeta potential of the second layer.

公开(公告)号：US09726650B2

公开(公告)日：2017-08-08

申请号：US14375677

申请日：2013-02-01

申请人： DAICEL CORPORATION

发明人： Toshiharu Minoda ,  Isamu Ikeda

IPC分类号： B01D15/08 ,  G01N30/93 ,  G01N30/92 ,  B01J20/291 ,  B01J20/32 ,  B01J20/285 ,  G01N30/94 ,  G01N30/88

CPC分类号： G01N30/92 ,  B01D15/08 ,  B01J20/291 ,  B01J2220/46 ,  B01J2220/54 ,  G01N30/93 ,  G01N2030/8877 ,  G01N2030/945

摘要： A chromatographic medium having a separating agent layer, which is used to separate target substances, a filling agent layer, which is used to fix the target substances before the target substances are separated, and a permeation layer, which is used to enable permeation of the target substances separated by the separating agent layer, wherein the filling agent layer comes into contact with the separating agent layer via a plane that intersects the direction of development of the target substances in the chromatographic medium and is positioned on the upstream side in the direction of development, the separating agent layer exhibits separability of the target substances and optical responsiveness to ultraviolet rays, and the permeation layer exhibits an optical responsiveness that is different from those of the target substances and the separating agent layer.

公开(公告)号：US20170191938A1

公开(公告)日：2017-07-06

申请号：US15394045

申请日：2016-12-29

申请人： INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE ,  NATIONAL TSING HUA UNIVERSITY

发明人： Ding-Zheng LIN ,  Ta-Jen YEN ,  Bi-Shen LEE ,  Chih-Hao HUANG

IPC分类号： G01N21/65 ,  G01N30/92

CPC分类号： G01J3/4412 ,  B82Y35/00 ,  G01N15/0211 ,  G01N21/65 ,  G01N21/658 ,  G01N30/92 ,  G01N30/95

摘要： A Raman detecting chip for thin layer chromatography and a method for separating and detecting an analyte are provided. The Raman detecting chip for thin layer chromatography includes a silicon substrate. The silicon substrate includes a flat portion and a plurality of silicon nanowires disposed on the flat portion, wherein each silicon nanowire has a top surface and a sidewall. A metal layer covers the top surface and at least a part of the sidewall. The silicon nanowire has a length from 5 μm to 15 μm.

公开(公告)号：US20150377847A1

公开(公告)日：2015-12-31

申请号：US14843762

申请日：2015-09-02

申请人： BRIGHAM YOUNG UNIVERSITY

发明人： Matthew R. Linford ,  Robert C. Davis ,  Richard Vanfleet ,  David S. Jensen ,  Li Yang ,  Jun Song

IPC分类号： G01N30/92 ,  B01J20/282 ,  B01J20/28 ,  G01N30/93 ,  B01D15/20

CPC分类号： G01N30/92 ,  B01D15/20 ,  B01J20/28007 ,  B01J20/282 ,  B01J20/286 ,  B01J2220/82 ,  B82Y30/00 ,  G01N30/93

摘要： In an embodiment, a method for manufacturing a thin layer chromatography (“TLC”) plate is disclosed. The method includes forming a layer of elongated nanostructures (e.g., carbon nanotubes), and at least partially coating the elongated nanostructures with a coating. The coating includes a stationary phase and/or precursor of a stationary phase for use in chromatography. At least a portion of the elongated nanostructures may be removed after being coated. Embodiments for TLC plates and related methods are also disclosed.

摘要翻译： 在一个实施方案中，公开了薄层色谱（“TLC”）板的制造方法。 该方法包括形成细长的纳米结构层（例如，碳纳米管），并且用涂层至少部分地涂覆细长的纳米结构。 涂层包括用于色谱法的固定相和/或固定相的前体。 至少一部分细长的纳米结构可以在被涂覆之后被去除。 还公开了TLC板的实施例和相关方法。

公开(公告)号：US5300564A

公开(公告)日：1994-04-05

申请号：US637873

申请日：1991-01-08

申请人： David Avnir ,  Michael Ottolenghi ,  Sergei Braun ,  Rivka Zusman

发明人： David Avnir ,  Michael Ottolenghi ,  Sergei Braun ,  Rivka Zusman

IPC分类号： C07K16/00 ,  B01J20/281 ,  B01J20/283 ,  B01J20/291 ,  C03B8/02 ,  C03C4/00 ,  C07K1/14 ,  C12N11/04 ,  C12N11/14 ,  C12P1/00 ,  C12Q1/00 ,  G01N21/77 ,  G01N27/327 ,  G01N30/02 ,  G01N30/88 ,  G01N30/92 ,  G01N31/22 ,  G01N33/543 ,  G01N33/552 ,  G01N33/68 ,  G01N33/84 ,  B01D53/00 ,  G01N21/00 ,  G01N33/00

CPC分类号： G01N33/6869 ,  B01J20/283 ,  B01J20/291 ,  C03C4/0007 ,  C12N11/14 ,  C12P1/00 ,  G01N31/22 ,  G01N33/5436 ,  G01N33/552 ,  G01N33/84 ,  B01J2220/54 ,  G01N2030/484 ,  G01N30/02 ,  G01N30/92 ,  Y02P20/588 ,  Y10S514/944 ,  Y10S514/965 ,  Y10S530/811 ,  Y10T428/2989 ,  Y10T436/10

摘要： A method is proposed of obtaining a chemical interaction between at least one reagent trapped in sol-gel glass by doping it with the reagent, and diffusible solutes or components in an adjacent liquid or gas phase. The reagents, the solutes or the components can be any organic or inorganic compounds or materials of biological origin including enzymes. The doped sol-gel glass in various forms may be useful as analytical test, chromatographic medium, sensor, catalyst or biocatalyst, electrode or enzyme electrode, or other detection device.

公开(公告)号：US5139680A

公开(公告)日：1992-08-18

申请号：US713382

申请日：1991-06-05

申请人： Yuri Tarnopolsky

发明人： Yuri Tarnopolsky

IPC分类号： B01D15/08 ,  G01N30/02 ,  G01N30/38 ,  G01N30/60 ,  G01N30/90 ,  G01N30/92

CPC分类号： G01N30/38 ,  B01D15/1892 ,  G01N2030/388 ,  G01N30/02 ,  G01N30/60 ,  G01N30/92

摘要： Continuous multicomponent separation is conducted in a two-dimensional anisotropic separation bed which has different separating properties in at least two directions, Y and X. The carrier fluid flows repeatedly and alternately in directions Y and X through the bed. The mixture is introduced into the flow in the vicinity of one of the corners. The components are collected through multiple outlets. An example of anisotropic bed is alternating layers of dense chromatographic packing with high separating ability and loose packing with low separating ability. Another example of anisotropic bed is tightly packed aligned fibrillar sorbent. Due to anisotropic properties of the bed, the components move along diverging resulting trajectories.

摘要翻译： 连续多组分分离在二维各向异性分离床中进行，该分离床在至少两个方向Y和X上具有不同的分离性能。载体流体在Y和X方向上反复交替地通过床。 将混合物引入到其中一个角附近的流中。 组件通过多个出口收集。 各向异性床的一个例子是具有高分离能力的密集色谱填料的交替层和具有低分离能力的松散填料。 各向异性床的另一个例子是紧密堆积的对准的纤维吸附剂。 由于床的各向异性特征，组件沿着发散的轨迹移动。

公开(公告)号：US4006069A

公开(公告)日：1977-02-01

申请号：US632884

申请日：1975-11-17

申请人： Nobuo Hiratsuka ,  Nakatsugu Yaginuma

发明人： Nobuo Hiratsuka ,  Nakatsugu Yaginuma

IPC分类号： G01N27/26 ,  B01D69/10 ,  G01N27/447 ,  G01N30/92 ,  G01N27/28

CPC分类号： G01N27/44747 ,  B01D69/10

摘要： A support for use in electrophoretic analysis comprising a porous polymeric flat plate such as filter paper, cellulose acetate or a non-woven fabric and a polymeric gel, such as polyacrylamide gel, enclosed in the open cells of the flat plate. The gel membrane is tough and does not shrink upon drying. The support can also be used as a filter.

摘要翻译： 用于电泳分析的载体，包括封闭在平板的开孔中的多孔聚合物平板如滤纸，乙酸纤维素或无纺织物以及聚合物凝胶如聚丙烯酰胺凝胶。 凝胶膜是坚韧的，干燥后不会收缩。 支撑也可以用作过滤器。

公开(公告)号：US3914174A

公开(公告)日：1975-10-21

申请号：US35744073

申请日：1973-05-04

申请人： CIBA GEIGY CORP

发明人： FUCHS HELMUT

IPC分类号： G01N30/92 ,  B01J20/281 ,  G01N30/90 ,  G01N30/95 ,  G01N31/08

CPC分类号： B01J20/281 ,  B01J2220/54 ,  G01N30/48 ,  G01N30/95

摘要： Layer material and method for the rapid chromatographic identification of liquid substances, yielding reproducible and distinct ring chromatograms said layer containing A. at least two dyestuffs and B. a substrate layer suitable for carrying out chromatographic tests, and wherein A. THE DYESTUFFS ARE IN A FINE AND EVEN STATE OF DISTRIBUTION AND ARE IN CONTACT WITH THE SUBSTRATE LAYER, B. AT LEAST TWO DYESTUFFS YIELD COLOUR RINGS WHICH CAN BE SUFFICIENTLY DISTINGUISHED BY THE EYE, AND C. THE DYESTUFFS AND SUBSTRATE ARE SO ADJUSTED TO EACH OTHER THAT THE ENTIRE SYSTEM IS ABLE TO FORM A RING CHROMATOGRAM SPECIFIC TO A LIQUID SUBSTANCE WHICH IS TO BE IDENTIFIED, BY DEPOSITING A SMALL AMOUNT OF A LIQUID TO BE TESTED FOR ITS CONTENT OF THE LIQUID SUBSTANCE TO BE IDENTIFIED, ON A POINT ON THE SAID SUBSTRATE LAYER AND COMPARING THE RESULTING CHROMATOGRAM WITH ONE WHICH HAS BEEN OBTAINED IN SIMILAR MANNER WITH A TEST SAMPLE OF THE LIQUID SUBSTANCE TO BE IDENTIFIED.

摘要翻译： 用于液体物质的快速色谱鉴定的层材料和方法，产生可再现和不同的环色谱图，所述层含有至少两种染料和B.适于进行色谱测试的底物层，其中A.在A 精细和甚至分配状态，并与基底层接触，B。至少两个可以被眼睛充分辨认的染色颜色的环，和C.染发剂和底物被调整到另外一个完整的系统 能够形成特定于需要识别的液体物质的环状色素，通过沉淀出液体物质的小量被测定，以便液体物质被识别的内容，位于合格基底层上的一点上，并且比较 具有与类似物质相似的样品的结果色谱与待鉴定的液体物质的测试样品。