公开(公告)号：US11933867B2

公开(公告)日：2024-03-19

申请号：US17720473

申请日：2022-04-14

Applicant: Bruker Switzerland AG

Inventor： Daniel Schmidig

IPC: G01R33/31 ,  G05D7/06

CPC classification number: G01R33/31 ,  G05D7/0635

Abstract: Temperature control system for an NMR sample tube (22) using a temperature control device (20) with an interior (21) delimiting a cylindrical wall (39) in the radially outward direction and a plurality of flow channels for temperature-controlling fluid running radially around the interior, of which the radially outermost flow channel (28) is delimited to the outside by a wall (29), and the innermost flow channel (31) by a wall (30) and connected to one another by a first fluid passage (34). The innermost flow channel has a second fluid passage (36) to the interior and the outermost flow channel has a fluid inlet (32). During operation, the wall delimiting the interior in the radially outward direction is temperature-controlled by the fluid so that: abs (TU−TW)≤abs (TU−TFD), where TW is the wall temperature, TFD is the fluid temperature at the first fluid passage and TU is the ambient temperature.

公开(公告)号：US20230184854A1

公开(公告)日：2023-06-15

申请号：US18066381

申请日：2022-12-15

Applicant: Bruker BioSpin GmbH

Inventor： Alexander KRAHN ,  David OSEN ,  Priyanga BANDARA ,  Jürgen GANZ

IPC: G01R33/30 ,  G01R33/31

CPC classification number: G01R33/307 ,  G01R33/31

Abstract: An apparatus for detachably fastening an NMR probe head with a pedestal box to an NMR magnet system of an NMR spectrometer has a holding system rigidly connected to the magnet system. A base plate of the holding system fastens detachably to the probe head pedestal box. A receiving device on or in the base plate receives all electric, electronic, optical, pneumatic, and thermal feed lines and optionally discharge lines required for the operation of the probe head. A lower side of the base plate in contact with an upper side of the pedestal box comprises multiple connecting elements into which the feed lines and discharge lines merge. The upper side of the pedestal box comprises receiving elements into which the feed lines and discharge lines from the connecting elements merge in a predetermined relative assembled position.

公开(公告)号：US20220137169A1

公开(公告)日：2022-05-05

申请号：US17465895

申请日：2021-09-03

Applicant: Massachusetts Institute of Technology

Inventor： Dirk Robert ENGLUND

IPC: G01R33/46 ,  G01R33/32 ,  G01R33/31 ,  G01R33/28

Abstract: Chemical-shift nuclear magnetic resonance (NMR) spectroscopy involves measuring the effects of chemical bonds in a sample on the resonance frequencies of nuclear spins in the sample. Applying a magnetic field to the sample causes the sample nuclei to emit alternating current magnetic fields that can be detected with color centers, which can act as very sensitive magnetometers. Cryogenically cooling the sample increases the sample's polarization, which in turn enhances the NMR signal strength, making it possible to detect net nuclear spins for very small samples. Flash-heating the sample or subjecting it to a magic-angle-spinning magnetic field (instead of a static magnetic field) eliminates built-in magnetic field inhomogeneities, improving measurement sensitivity without degrading the sample polarization. Tens to hundreds of small, cryogenically cooled sample chambers can be integrated in a semiconductor substrate interlaced with waveguides that contain color centers for optically detected magnetic resonance measurements of the samples' chemical-shift NMR frequencies.

公开(公告)号：US11131722B2

公开(公告)日：2021-09-28

申请号：US16718787

申请日：2019-12-18

Applicant: TDK—Micronas GmbH

Inventor： Oliver Kawaletz ,  Martin Cornils

IPC: G01R33/31 ,  G01R33/00

Abstract: An apparatus (10) for checking a component (30) is disclosed. The apparatus (10) comprises a sample holder (20) with a module (28) for receiving at least one component (30), at least one magnetic field generator (60a, 60b, 60c) for generating a magnetic field around the module (28), an inlet (40) for feeding a tempered medium into the module (25), and an outlet (45) for discharging a tempered medium from the module (28).

公开(公告)号：US20210239632A1

公开(公告)日：2021-08-05

申请号：US17168552

申请日：2021-02-05

Applicant: W. D. Von Gonten Laboratories, LLC

Inventor： Safdar Ali ,  Ashish Mathur ,  Chad Belanger

IPC: G01N24/08 ,  G01N33/24 ,  G01R33/30 ,  G01R33/31 ,  G01R33/46

Abstract: Methods for determining a volume of stored gas within a rock sample includes loading a rock sample into an overburden cell. A hydrocarbon gas at a gas pressure is applied to the rock sample and a confining fluid at a confining pressure is applied to the overburden cell. The confining pressure and the gas pressure are increased until a first pressure and temperature condition is met. With the rock sample maintained at the first temperature and pressure condition, a nuclear magnetic resonance spectrometer is used to scan the rock sample and measure a hydrocarbon gas volume within the rock sample. This measured hydrocarbon gas volume is then corrected using a Real Gas Index to determine the volume of stored gas within the rock sample.

公开(公告)号：US20210181275A1

公开(公告)日：2021-06-17

申请号：US16768801

申请日：2018-11-29

Applicant: Washington University

Inventor： Alexander Barnes

IPC: G01R33/30 ,  G01R33/46 ,  G01R33/31

Abstract: Among the various aspects of the present disclosure is the provision of systems and spherical rotors suitable for use in magic angle spinning (MAS) nuclear magnetic resonance (NMR) spectroscopy and methods of use thereof.

公开(公告)号：US11035807B2

公开(公告)日：2021-06-15

申请号：US15915015

申请日：2018-03-07

Applicant: GENERAL ELECTRIC COMPANY

Inventor： Ernst Wolfgang Stautner ,  Eric George Budesheim

IPC: G01N24/08 ,  F25D19/00 ,  F25D29/00 ,  F28F13/00 ,  F28F21/08 ,  G01N1/42 ,  G01N35/00 ,  G01R33/28 ,  G01R33/31

Abstract: A cooling system, an apparatus for producing hyperpolarized samples, where the apparatus includes the cooling system, and a method for assembling and using the cooling system are disclosed. The cooling system includes a cryogenic chamber, a cooling plate, a sample sleeve, a thermal switch, and an interposer. Also, the cryogenic chamber includes a cryogenic fluid and the cooling plate is disposed in the cryogenic chamber, in contact with the cryogenic fluid. Further, the sample sleeve is configured to receive a sample. The sample sleeve is at least partially inserted in the cryogenic chamber. The thermal switch is disposed between the cooling plate and the sample sleeve. Moreover, the interposer is disposed between at least one of (i) the thermal switch and the cooling plate and (ii) the thermal switch and the sample sleeve. The interposer includes a gallium indium tin alloy.

公开(公告)号：US10908237B2

公开(公告)日：2021-02-02

申请号：US15945512

申请日：2018-04-04

Applicant: Howard Hughes Medical Institute

Inventor： Mladen Barbic

IPC: G01R33/31 ,  G01R33/3815 ,  A61K49/06 ,  A61B5/055 ,  G01R33/56 ,  A61N2/00 ,  A61B5/05 ,  A61B5/01 ,  G01R33/28

Abstract: An apparatus includes a magnetic apparatus that defines an actuation volume that is large enough to accommodate a sample, the magnetic apparatus including a magnet that is configured to create a magnetic field having a magnitude B in the sample when supplied with a DC current; at least one biological construct within the sample, the biological construct configured to change its status in response to a change in a property; and at least one magnetocaloric actuator coupled with the biological construct. A change in a characteristic in the actuation volume causes the property of the magnetocaloric actuator to change, which causes a change in the status of the biological construct.

公开(公告)号：US10884155B2

公开(公告)日：2021-01-05

申请号：US16157480

申请日：2018-10-11

Applicant: PetroChina Company Limited

Inventor： Hua Tian ,  Shuichang Zhang ,  Shaobo Liu ,  Caineng Zou ,  Keyu Liu ,  Xuesong Lu ,  Mengjun Zhao ,  Lin Jiang ,  Xingzhi Ma ,  Bin Zhang ,  Junjia Fan ,  Peiqiang Yang

IPC: G01N24/08 ,  G01R33/483 ,  G01R33/44 ,  G01R33/54 ,  G01R33/561 ,  G01R33/31 ,  G01R33/48 ,  G01R33/563 ,  G01V3/32

Abstract: A method and an apparatus for measuring oil content of a tight reservoir based on nuclear magnetic resonance includes applying a pulse sequence to a tight reservoir rock, and after applying a first pulse and a last pulse in the pulse sequence, applying a gradient magnetic field to the tight reservoir rock, respectively, directions of the two applied gradient magnetic fields being opposite to each other, wherein the pulse sequence is composed of three 90° pulses; acquiring a nuclear magnetic resonance signal of the tight reservoir rock; and determining oil content of the tight reservoir rock according to an intensity of the nuclear magnetic resonance signal. The method can accurately distinguish an oil phase nuclear magnetic resonance signal and a water phase nuclear magnetic resonance signal in nanopores of tight reservoir rock, thereby effectively improving the accuracy of the detection result of the oil content of the tight reservoir rock.

公开(公告)号：US10802102B2

公开(公告)日：2020-10-13

申请号：US16331457

申请日：2018-03-08

Applicant: UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA

Inventor： Zongquan Zhou ,  Peiyun Li ,  Chao Liu ,  Xiao Liu ,  Chuanfeng Li ,  Guangcan Guo

IPC: G01R33/60 ,  G01R33/31

Abstract: A pulsed electron paramagnetic resonance spectrometer comprises: a microwave excitation generating unit for generating at least one microwave pulse; a microwave conducting unit comprising a resonant cavity and a microwave transmission line for transmitting microwaves, wherein the microwave transmission line is connected between the microwave excitation generating unit and the resonant cavity, and the resonant cavity is for placing a sample; a cryostat and magnet unit comprising a cryostat that performs ultra-low temperature cooling for the microwave resonant cavity, the microwave transmission line being disposed to pass through the cryostat and connected to the resonant cavity; the cryostat and magnet unit further comprises a magnet that provides a resonance test magnetic field around the sample, the resonant cavity being disposed in a room temperature gap of the magnet. The device of the present disclosure characteristics in ultra-low sample temperature (0.1 Kelvin) and is fully functional and easy to operate.