Methods and apparatus for authenticating articles with luminescent phosphor compounds
    2.
    发明授权
    Methods and apparatus for authenticating articles with luminescent phosphor compounds 有权
    用发光荧光体化合物认证物品的方法和装置

    公开(公告)号:US09239262B2

    公开(公告)日:2016-01-19

    申请号:US13537414

    申请日:2012-06-29

    摘要: Methods and apparatus for article authentication include an exciting radiation generator that exposes an area of the article to exciting radiation, and at least two radiation detectors that detect emitted radiation from the area in a first band and in a second band that does not overlap the first band. The first band corresponds with a first emission sub-band of an emitting ion, and the second band corresponds with a second emission sub-band of the same emitting ion. A processing system calculates a comparison value that represents a mathematical relationship (e.g., a ratio) between a first intensity of the emitted radiation in the first band with a second intensity of the emitted radiation in the second band, and determines whether the comparison value compares favorably with an authentication parameter. When the comparison value compares favorably with the authentication parameter, the article is identified as being authentic.

    摘要翻译: 用于物品认证的方法和装置包括将物品的区域暴露于激发辐射的激发辐射发生器,以及至少两个辐射检测器,其检测来自第一频带中的区域和不与第一频带重叠的第二频带中的区域的发射辐射 带。 第一带对应于发射离子的第一发射子带,第二带对应于相同发射离子的第二发射子带。 处理系统计算表示第一频带中发射的辐射的第一强度与第二频带中发射的辐射的第二强度之间的数学关系(例如,比率)的比较值,并且确定比较值是否比较 有利于认证参数。 当比较值与验证参数相比较时,该物品被识别为真实的。

    Measurement system
    3.
    发明授权
    Measurement system 失效
    测量系统

    公开(公告)号:US07466408B2

    公开(公告)日:2008-12-16

    申请号:US10287658

    申请日:2002-11-05

    申请人: Takeo Tanaami

    发明人: Takeo Tanaami

    CPC分类号: G01N21/6452 G01N2021/6482

    摘要: A measurement system that optically measures in turn a plurality of samples arranged in an array via an objective lens and an imaging lens is disclosed, which is characterized by comprising an actuator means that moves the above described objective lens corresponding to each position of the above mentioned samples, and a photo-detecting part that detects a sample image via the above objective lens and imaging lens.

    摘要翻译: 公开了一种测量系统,其通过物镜和成像透镜来依次光学地测量以阵列布置的多个样本,其特征在于包括致动器装置,该致动器装置将上述物镜移动到与上述 样品和经由上述物镜和成像透镜检测样本图像的光检测部分。

    Method and device for conducting the spectral differentiating, imaging measurement of fluorescent light
    6.
    发明授权
    Method and device for conducting the spectral differentiating, imaging measurement of fluorescent light 有权
    用于进行光谱分化,荧光成像测量的方法和装置

    公开(公告)号:US07304733B2

    公开(公告)日:2007-12-04

    申请号:US10515673

    申请日:2003-05-15

    摘要: A method and a device for image producing measurement of fluorescent light, according to which a sample containing fluorophores of different species is irradiated with excitation light of at least one excitation channel defined by its spectral properties. The fluorescent light emitted by the sample is received by at least one detection channel defined by its spectral detection characteristic, and is converted into a digital signal, which is stored for further processing The properties of a number of measuring channels, respectively defined as specific combinations consisting of an excitation channel and a detection channel, are automatically set before conducting the measurement according to the result of a mathematical optimization process, which takes into account the fluorescence characteristics of at least some of the fluorophores presumed by the user to be in the sampler.

    摘要翻译: 用于产生荧光测量的图像的方法和装置,根据该方法和装置,使用由其光谱特性限定的至少一个激发通道的激发光照射含有不同种类的荧光团的样品。 由样本发射的荧光被由其光谱检测特性限定的至少一个检测通道接收,并被转换为数字信号,该信号被存储用于进一步处理。多个测量通道的特性分别被定义为特定组合 由激励信道和检测信道构成的信号在根据数学优化处理的结果进行测量之前被自动设置,该数学优化过程考虑了用户假设在采样器中的至少一些荧光团的荧光特性 。

    Polychronic laser scanning system and method of use
    7.
    发明授权
    Polychronic laser scanning system and method of use 失效
    多功能激光扫描系统及其使用方法

    公开(公告)号:US07248360B2

    公开(公告)日:2007-07-24

    申请号:US11090673

    申请日:2005-03-25

    摘要: A system for laser scanning provides spectral flexibility needed for the spectroscopic monitoring of highly multiplexed samples, such as cellular and particle assays in whole blood or other suspensions. In accordance with embodiments of the present invention, the system comprises a scanner to direct an excitation laser through a sample, an objective to collect light emitted by the sample in response to the excitation laser, a spectrograph to disperse the emitted light over a plurality of wavelengths as a spectrum, and a charge coupled device for detecting the spectrum. The system can be used with samples having a variety of reporter tags, including one or more SERS tags, fluorescent organic and protein tags, and quantum dot tags. A laser scanning apparatus and method of using the same is also provided.

    摘要翻译: 用于激光扫描的系统提供了高分辨率样品的光谱监测所需的光谱灵活性,例如全血或其它悬浮液中的细胞和颗粒测定。 根据本发明的实施例,该系统包括扫描器,用于将激发激光引导通过样本,用于响应于激发激光收集由样本发射的光的目标,将发射的光分散在多个 波长作为光谱,以及用于检测光谱的电荷耦合器件。 该系统可以与具有各种报告标签的样品一起使用,包括一个或多个SERS标签,荧光有机和蛋白质标签以及量子点标签。 还提供了一种激光扫描装置及其使用方法。

    Radioactive marker
    8.
    发明授权
    Radioactive marker 失效
    放射性标记

    公开(公告)号:US5521391A

    公开(公告)日:1996-05-28

    申请号:US100610

    申请日:1993-07-30

    申请人: Sergio Bocian

    发明人: Sergio Bocian

    摘要: A radioactive marker including a housing and a light module disposed in the housing, the light module including a tritium light source disposed in a light source housing.

    摘要翻译: 一种放射性标记,包括设置在壳体中的壳体和光模块,该光模块包括设置在光源壳体中的氚光源。

    System and method for metered dosage illumination in a bioanalysis or other system
    10.
    发明授权
    System and method for metered dosage illumination in a bioanalysis or other system 有权
    生物分析或其他系统中计量剂量照明的系统和方法

    公开(公告)号:US08466436B2

    公开(公告)日:2013-06-18

    申请号:US13282108

    申请日:2011-10-26

    摘要: A system and method for metered dosage illumination in a bioanalysis or other system includes an illumination system or subsystem that can provide optimized amounts of excitation light within the short exposure times necessary to measure fast biological activity. The amount of light can be precisely measured to provide quantitative results. The light flux can be precisely controlled to generate a prescribed minimum amount of light, in order to reduce adverse lighting effects on both fluors and samples. The system and method is particularly useful in any quality-control, analysis, or assessment-based environment. Typical research and development applications can include quality control, instrument calibration, and light output standardization; while clinical and diagnostics applications can include clinical monitoring, bioassay calibration and control for diagnostics, treatment and or therapeutic evaluation.

    摘要翻译: 在生物分析或其他系统中的计量剂量照明的系统和方法包括照明系统或子系统,其可以在测量快速生物活性所需的短曝光时间内提供优化量的激发光。 可以精确测量光量以提供定量结果。 可以精确地控制光通量以产生规定的最小量的光,以便减少对荧光和样品的不利的照明效果。 该系统和方法在任何质量控制,分析或评估环境中特别有用。 典型的研发应用包括质量控制,仪器校准和光输出标准化; 而临床和诊断应用可以包括用于诊断,治疗和/或治疗评估的临床监测,生物测定校准和控制。