Steroidal piperidone derivative, synthesis method, and use thereof

    公开(公告)号:US11751567B2

    公开(公告)日:2023-09-12

    申请号:US17951129

    申请日:2022-09-23

    IPC分类号: A01N43/42 A01P7/04 C07J73/00

    CPC分类号: A01N43/42 A01P7/04 C07J73/005

    摘要: A steroidal piperidone derivative, a synthesis method, and a use thereof are provided. The steroidal piperidone derivative has a chemical structure shown in general formula (1) or general formula (2), where R is any one selected from the group consisting of alkyl, phenyl, substituted phenyl, and a heterocycle. In the synthesis method of the steroidal piperidone derivative, dehydroepiandrosterone (DHEA) is used as a basic raw material to prepare the steroidal piperidone derivative of the present disclosure through a series of reactions. A product prepared by the synthesis method has a high yield and is easily separated, and thus the synthesis method is the optimal method for preparing the steroidal piperidone derivative of the present disclosure. The present steroidal piperidone derivative exhibits prominent toxic activity against sucking pests, such as aphids, spider mites, rice planthoppers, and B. tabaci, and can be used for the control of a plant pest.