公开(公告)号：US12128128B2

公开(公告)日：2024-10-29

申请号：US16499406

申请日：2018-03-29

申请人： Phyto Sophos Ltd.

发明人： Laura Dewar

IPC分类号： A61K8/9789 ,  A61K8/02 ,  A61K8/19 ,  A61K8/9741 ,  A61K8/9755 ,  A61K8/9783 ,  A61K8/9794 ,  A61K9/00 ,  A61K33/38 ,  A61K36/11 ,  A61K36/14 ,  A61K36/185 ,  A61K36/25 ,  A61K36/258 ,  A61K36/28 ,  A61K36/29 ,  A61K36/30 ,  A61K36/36 ,  A61K36/38 ,  A61K36/48 ,  A61K36/66 ,  A61K36/70 ,  A61K36/74 ,  A61K36/886 ,  A61L26/00 ,  A61P17/02 ,  A61Q19/00

CPC分类号： A61K8/9789 ,  A61K8/0208 ,  A61K8/19 ,  A61K8/9794 ,  A61Q19/00

摘要： In one aspect, a composition for topical application is provided. The composition comprises a base. Dispersed within the base is elemental silver as a colloidal suspension, and plant extract from at least 6 plants. The plants are selected from the group consisting of Echinacea purpurea, Stellaria media, Aloe vera, Matricaria recutita, Hypericum perforatum, Calendula officinalis, Equisetum arvense, Symphytum officinale, Panax ginseng, Rumex crispus, Arctium lappa, Trifolium pratense, Chelidonium majus, Thuja occidentalis, Urtica dioica, Mahonia aquifolium, and Galium aparine.

公开(公告)号：US20240335496A1

公开(公告)日：2024-10-10

申请号：US18421911

申请日：2024-01-24

申请人： INFINITUS (CHINA) COMPANY LTD.

发明人： Lei XIAO ,  Lingling HE ,  Jinlian HUANG ,  Yan GAO

IPC分类号： A61K36/718 ,  A61K9/00 ,  A61K9/06 ,  A61K36/28 ,  A61K36/346 ,  A61K36/42 ,  A61K36/484 ,  A61K36/53 ,  A61K36/539 ,  A61K36/725 ,  A61K36/752 ,  A61K36/808 ,  A61K36/88 ,  A61K36/9068 ,  A61K47/10 ,  A61K47/26 ,  A61K47/38 ,  A61P1/04

CPC分类号： A61K36/718 ,  A61K9/006 ,  A61K9/06 ,  A61K36/28 ,  A61K36/346 ,  A61K36/42 ,  A61K36/484 ,  A61K36/53 ,  A61K36/539 ,  A61K36/725 ,  A61K36/752 ,  A61K36/808 ,  A61K36/88 ,  A61K36/9068 ,  A61K47/10 ,  A61K47/26 ,  A61K47/38 ,  A61P1/04 ,  A61K2236/15 ,  A61K2236/53

摘要： The present invention is related to a modified prescription of Gancao Xiexin decoction and the use thereof. The modified prescription of Gancao Xiexin decoction of the present invention mainly contains Coptidis Rhizoma, Scutellariae Radix, Glycyrrhizae Radix et Rhizoma, Zingiberis Rhizoma, Jujubae Fructus, Citri Reticulatae Pericarpium and Bolbostemmatis Rhizoma with effects of alleviating inflammatory reaction and promoting oral healing, and can be used for treating oral ulcer or for preparing a product for treating oral ulcer, which helps reduce the recurrence of oral ulcer. Meanwhile, the present invention also provides a soft gel containing the aqueous extract of the modified prescription of Gancao Xiexin decoction, which has a simple composition, does not contain toxic traditional Chinese medicine, can be administered by coating oral ulcer, is convenient to use and has a good therapeutic effect.

公开(公告)号：US12097231B2

公开(公告)日：2024-09-24

申请号：US18328066

申请日：2023-06-02

申请人： CARGILL, INCORPORATED

发明人： Dan S. Gaspard ,  Adam John Steinbach ,  Adam T. Zarth

IPC分类号： A23L27/30 ,  A23F3/34 ,  A23L2/56 ,  A23L2/60 ,  A23L2/68 ,  A23L5/40 ,  A23L27/00 ,  A61K31/192 ,  A61K31/235 ,  A61K36/28 ,  B01D15/36 ,  C07H15/256 ,  C07K1/16 ,  C07K1/18

CPC分类号： A61K36/28 ,  A23F3/34 ,  A23L2/56 ,  A23L2/60 ,  A23L2/68 ,  A23L5/40 ,  A23L27/30 ,  A23L27/36 ,  A23L27/39 ,  A23L27/88 ,  A61K31/192 ,  A61K31/235 ,  B01D15/361 ,  C07H15/256 ,  C07K1/16 ,  C07K1/18 ,  A23V2002/00 ,  A23V2200/15 ,  A23V2250/258 ,  A61K2236/31 ,  A61K2236/39

摘要： A steviol glycoside composition with reduced surface tension. The reduced surface tension steviol glycoside composition includes an aqueous solution of a steviol glycoside and a surface tension reducing compound in an amount effective to reduce surface tension. Method for reducing surface tension in a steviol glycoside solution includes contacting a steviol glycoside and a surface tension reducing compound.

公开(公告)号：US12090185B2

公开(公告)日：2024-09-17

申请号：US17813724

申请日：2022-07-20

申请人： SUPER CRITICAL IP, LLC

发明人： Armand J. Noel

IPC分类号： C07D311/80 ,  A61K31/05 ,  A61K31/352 ,  A61K36/185 ,  A61K36/28 ,  C07C37/00 ,  C07C37/74 ,  C07C37/84

CPC分类号： A61K36/28 ,  A61K31/05 ,  A61K31/352 ,  A61K36/185 ,  C07C37/003 ,  C07C37/74 ,  C07C37/84 ,  C07D311/80 ,  A61K2236/35 ,  A61K2236/37 ,  A61K2236/51 ,  A61K2236/53 ,  C07B2200/13 ,  C07C2601/16

摘要： Some variations provide a process of converting a cannabinoid into a purified cannabinoid derivative, comprising: providing a starting composition comprising a cannabinoid; providing a C9-C11 non-aromatic hydrocarbon solvent; introducing the starting composition and the solvent to a conversion reactor; chemically converting some, but not all, of the cannabinoid to a cannabinoid derivative, generating a reaction mixture containing unreacted cannabinoid; conveying the reaction mixture to a crystallization unit; cooling the reaction mixture to precipitate unreacted cannabinoid out of the reaction mixture, thereby generating a mother liquor containing the cannabinoid derivative; and isolating and recovering the cannabinoid derivative from the mother liquor. Systems configured to carry out the disclosed processes are also provided. This invention offers a large-scale solution to economically convert CBD to D9-THC, among many other example. The principles of the invention may be applied to the conversion of various cannabinoids and terpenes into derivative products.

公开(公告)号：US20240293489A1

公开(公告)日：2024-09-05

申请号：US18664874

申请日：2024-05-15

申请人： Housey Pharmaceutical Research Laboratories, L.L.C.

发明人： Gerard M. Housey ,  Monica Elizabeth Balash

IPC分类号： A61K36/28 ,  A61K31/155 ,  A61K31/40 ,  A61K31/4985 ,  A61K38/26 ,  A61K38/28 ,  A61K45/06 ,  G01N33/50

CPC分类号： A61K36/28 ,  A61K31/155 ,  A61K31/40 ,  A61K31/4985 ,  A61K38/26 ,  A61K38/28 ,  A61K45/06 ,  G01N33/5008 ,  A61K2300/00 ,  G01N2333/4703 ,  G01N2500/10

摘要： This invention relates to plant extracts containing nutritionally beneficial or medicinally active compounds. Some of these extracts, or the purified compounds contained therein, may be used for the nutritional support, prevention, treatment, or possible curc of various metabolic and other diseases and disorders in human beings and animals, including type 1 and type 2 diabetes, by regulating insulin signaling. This regulatory effect may include modulations of the levels and/or activity of the Insulin Receptor (IR), the Insulin-like Growth Factor (IGF) Receptor, and/or the Insulin Receptor Substrate (IRS) proteins in cells and tissues in the body.

公开(公告)号：US12076305B2

公开(公告)日：2024-09-03

申请号：US15025105

申请日：2014-09-19

申请人： CALSCIENCE INTERNATIONAL LTD

发明人： Iain William George Forbes ,  William Forbes

IPC分类号： A61K31/216 ,  A01N1/02 ,  A61K8/37 ,  A61K8/9789 ,  A61K8/9794 ,  A61K36/28 ,  A61K45/06 ,  A61K47/55 ,  A61Q7/00 ,  A61Q19/00 ,  A61Q19/06 ,  A61Q19/08

CPC分类号： A61K31/216 ,  A01N1/0205 ,  A61K8/37 ,  A61K8/375 ,  A61K8/9789 ,  A61K8/9794 ,  A61K36/28 ,  A61K45/06 ,  A61K47/55 ,  A61Q7/00 ,  A61Q19/00 ,  A61Q19/06 ,  A61Q19/08

摘要： Use of a composition for the for the prevention, amelioration and/or treatment of disorders and diseases involving cell, tissue or organ senescence, or for the prevention, amelioration and/or treatment of disorders and diseases involving cell, tissue or organ stress caused by an inflammatory process, the composition comprising a conjugate of quinic acid with at least one molecule of caffeic acid, or a derivative, isomer or salt thereof.

公开(公告)号：US20240285721A1

公开(公告)日：2024-08-29

申请号：US18659701

申请日：2024-05-09

申请人： HAUS BIOCEUTICALS, INC.

发明人： Tomy YESUDAS ,  Philip ALEX ,  Michael CENTOLA ,  Adam Joshua PAYNE

IPC分类号： A61K36/90 ,  A61K36/185 ,  A61K36/22 ,  A61K36/23 ,  A61K36/24 ,  A61K36/27 ,  A61K36/28 ,  A61K36/29 ,  A61K36/31 ,  A61K36/35 ,  A61K36/48 ,  A61K36/66 ,  A61K36/68 ,  A61K36/71 ,  A61K36/76 ,  A61K36/77 ,  A61K36/808 ,  A61K36/899

CPC分类号： A61K36/90 ,  A61K36/185 ,  A61K36/22 ,  A61K36/23 ,  A61K36/24 ,  A61K36/27 ,  A61K36/28 ,  A61K36/29 ,  A61K36/31 ,  A61K36/35 ,  A61K36/48 ,  A61K36/66 ,  A61K36/68 ,  A61K36/71 ,  A61K36/76 ,  A61K36/77 ,  A61K36/808 ,  A61K36/899

摘要： Disclosed herein are herbal formulations for relief from symptoms of skin disease. The formulations can also be combined with an active or inactive pharmaceutical ingredient, and/or a pharmaceutically acceptable excipient.

公开(公告)号：US20240269196A1

公开(公告)日：2024-08-15

申请号：US18415498

申请日：2024-01-17

申请人： Hofseth Biocare ASA

发明人： Bomi FRAMROZE

IPC分类号： A61K35/60 ,  A61K31/05 ,  A61K31/20 ,  A61K31/201 ,  A61K31/202 ,  A61K31/353 ,  A61K31/365 ,  A61K31/575 ,  A61K36/28 ,  A61K38/07 ,  A61K38/08 ,  A61K38/12 ,  A61P11/06 ,  A61P37/06

CPC分类号： A61K35/60 ,  A61K31/05 ,  A61K31/20 ,  A61K31/201 ,  A61K31/202 ,  A61K31/353 ,  A61K31/365 ,  A61K31/575 ,  A61K36/28 ,  A61K38/07 ,  A61K38/08 ,  A61K38/12 ,  A61P11/06 ,  A61P37/06

摘要： Provided herein are methods for treating certain inflammatory and/or respiratory conditions, disorders and diseases in humans using salmonid oil compositions. The salmonid oil compositions are orally administered, and may be obtained from mild enzymatic hydrolysis of off-cuts of salmonid fish. The humans suitable for such treatments include those largely resistant to medical and surgical interventions, such as steroid treatments. The salmonid oil compositions described herein have also been found to reduce eosinophil effector function.

公开(公告)号：US20240238302A1

公开(公告)日：2024-07-18

申请号：US18096471

申请日：2023-01-12

申请人： CHRISTOPHER MILLER

发明人： CHRISTOPHER MILLER

IPC分类号： A61K31/522 ,  A61J7/00 ,  A61K9/00 ,  A61K9/06 ,  A61K9/20 ,  A61K31/05 ,  A61K31/122 ,  A61K31/198 ,  A61K31/525 ,  A61K33/06 ,  A61K36/185 ,  A61K36/28 ,  A61K36/53 ,  A61K36/534 ,  A61K36/81 ,  A61K36/9068

CPC分类号： A61K31/522 ,  A61J7/0084 ,  A61K9/0014 ,  A61K9/006 ,  A61K9/06 ,  A61K9/20 ,  A61K31/05 ,  A61K31/122 ,  A61K31/198 ,  A61K31/525 ,  A61K33/06 ,  A61K36/185 ,  A61K36/28 ,  A61K36/53 ,  A61K36/534 ,  A61K36/81 ,  A61K36/9068

摘要： The invention provides a kit for migraine management. More specifically at least three pharmaceutical compounds are provided which seek, in combination, to provide relief to a migraine sufferer in the instance of a present migraine event.

公开(公告)号：US20240226216A1

公开(公告)日：2024-07-11

申请号：US18416129

申请日：2024-01-18

申请人： MARY KAY INC.

发明人： Tiffany CARLE ,  Geetha KALAHASTI ,  Shona BURKES ,  David Gan

IPC分类号： A61K36/28 ,  A61K8/44 ,  A61K8/67 ,  A61K8/9789 ,  A61K9/00 ,  A61K36/23 ,  A61K36/61 ,  A61K36/73 ,  A61K47/10 ,  A61Q19/06

CPC分类号： A61K36/28 ,  A61K8/44 ,  A61K8/676 ,  A61K8/9789 ,  A61K9/0014 ,  A61K36/23 ,  A61K36/61 ,  A61K36/73 ,  A61K47/10 ,  A61Q19/06

摘要： A method of treating fine lines or wrinkles in a person's skin or treating a person's sagging or loose skin is disclosed. The method can include topically applying to the fine line or wrinkle or to sagging or loose skin an effective amount of a topical composition comprising a Myrciaria dubia fruit extract, a Peucedanum graveolens extract, and tetrahexyldecyl ascorbate, wherein the combination reduces the appearance of the fine line or wrinkle, increases skin elasticity, or increases skin firmness.