MAGNETIC RESONANCE SIGNATURE MATCHING (MRSIGMA) FOR REAL-TIME VOLUMETRIC MOTION TRACKING AND ADAPTIVE RADIOTHERAPY

    公开(公告)号:US20250065153A1

    公开(公告)日:2025-02-27

    申请号:US18629415

    申请日:2024-04-08

    Abstract: Described is an approach for tracking 3D organ motion in real-time using magnetic resonance imaging (MRI). The approach may include offline learning, which may acquire signature and 3D imaging data over multiple respiratory cycles to create a database of high-resolution 3D motion states. The approach may further include online matching, which may acquire signature data only in real-time (latency less than 0.2 seconds). From a motion state and motion signature database, the 3D motion state whose signature best (or sufficiently) matches the newly-acquired signature data may be selected. Real-time 3D motion tracking may be accomplished by performing time-consuming acquisition and reconstruction work in an offline learning phase, leaving just signature acquisition and correlation analysis in an online matching step, minimizing or otherwise reducing latency. The approach may be used to adapt radiotherapy procedures based on tumor motion using a magnetic resonance linear accelerator (MR-Linac) system.

    METHOD FOR GENERATING TREATMENT PLAN, COMPUTER DEVICE, AND STORAGE MEDIUM

    公开(公告)号:US20250065150A1

    公开(公告)日:2025-02-27

    申请号:US18454344

    申请日:2023-08-23

    Abstract: Provided is a method for generating an arc treatment plan. The method for generating the arc treatment plan includes: generating a plurality of sub-regions by partitioning a region of interest based on an irradiation duration corresponding to the region of interest in a target volume; and generating the arc treatment plan for the target volume based on the plurality of sub-regions and irradiation durations corresponding to the plurality of sub-regions; wherein the irradiation durations corresponding to the plurality of sub-regions are all less than or equal to a predetermined value, a sum of the irradiation durations corresponding to the plurality of sub-regions is equal to an irradiation duration corresponding to the region of interest, and irradiation positions corresponding to the plurality of sub-regions are the same as an irradiation position corresponding to the region of interest.

    DEVICE FOR GENERATING MAGNETIC FIELD AND METHOD FOR CONTROLLING SAME

    公开(公告)号:US20250065086A1

    公开(公告)日:2025-02-27

    申请号:US18948170

    申请日:2024-11-14

    Applicant: RADEXEL INC.

    Inventor: Jeong Won LEE

    Abstract: Disclosed is a radiation and magnetic field generating apparatus irradiating photon beam radiation to in-body affected tissue of a subject including a radiation generating unit that irradiates the photon beam radiation to the subject and induces generation of secondary electrons in an area of the subject where the photon beam radiation is irradiated, a magnetic field generating unit, which is provided to be inserted into a body, which includes an insertion structure for forming a low-density space, and which forms a magnetic field in an area in which the secondary electrons are generated, and a synchronization control unit that controls formation of the magnetic field such that a part of the secondary electrons moves to the low-density space based on a relationship between an area where the photon beam radiation is irradiated and a location of an affected part, and controls the formation of the magnetic field.

    Intraoral positioning device
    5.
    发明授权

    公开(公告)号:US12233283B2

    公开(公告)日:2025-02-25

    申请号:US18070397

    申请日:2022-11-28

    Abstract: An intraoral positioning device (IPD) is disclosed for positioning in a patient's mouth for radiation therapy planning and treatment, the device comprising an engagement member configured to engage structure within a patient's mouth during radiation planning or treatment, wherein the engagement member includes an upper wall, a lower wall and first and second side walls extending from and between the upper and lower walls, whereby the upper, lower and first and second side walls form top, bottom, front and rear walls of a bite block, and a handle extending from the engagement member to enable a user to grasp the IPD for introducing and removing it from the patient's mouth.

    Apparatus for effecting feedback of vaginal cavity physiology

    公开(公告)号:US12232794B2

    公开(公告)日:2025-02-25

    申请号:US17328972

    申请日:2021-05-24

    Inventor: Alan N. Schwartz

    Abstract: A vaginal device is described. A conformable vaginal insert is shaped for insertion into a vaginal cavity of a female human. A contact point is configured to change a shape of the insert. A sensor is configured to measure and to relay characteristics of the vaginal cavity and the surrounding and supportive structures of the vaginal cavity. A processor is configured to control the contact point to adjust the shape of the insert, generate a treatment for the vaginal cavity and the surrounding structures of the vaginal cavity and the supportive structures of the vaginal cavity comprising a vaginal cavity profile generated from the measured characteristics, store the measured characteristics and the vaginal cavity profile, and based on the stored measured characteristics and the stored vaginal cavity profile, automatically modify the shape of the insert by control of the contact point to provide the treatment to the vaginal cavity.

    PULSATING BRACHYTHERAPY METHOD AND SYSTEM

    公开(公告)号:US20250058145A1

    公开(公告)日:2025-02-20

    申请号:US18935287

    申请日:2024-11-01

    Abstract: The invention provides a method for treating a tumor excise site defined by a center and edges, and includes simultaneously exposing the tumor site to radiation and pulsating heat. The invention also provides a device for treating tumors at a target site, the including a first balloon containing a radio isotope; a second balloon encasing the first balloon wherein the second balloon comprises structures to create a void between the first balloon and the second balloon; wherein the void is adapted to receive pulsing, temperature treated fluid.

    Motion tracking in magnetic resonance imaging using RADAR and a motion detection system

    公开(公告)号:US12228635B2

    公开(公告)日:2025-02-18

    申请号:US17045163

    申请日:2019-03-29

    Abstract: The invention provides for a medical instrument (100, 300, 400, 500) comprising a magnetic resonance imaging system (102). The medical instrument further comprises a subject support (120) with a support surface (121) configured for supporting at least a portion of the subject within an imaging zone (108). The subject support comprises a radar array (125) embedded below the support surface. The medical instrument further comprises a radar system (124) for acquiring a radar signal (144) from the subject. The medical instrument further comprises a motion detection system (122) configured for acquiring a movement signal (146). Execution of machine executable instructions (140) causes a processor (130) to: continuously (200) receive the radar signal; continuously (202) receive the movement signal; continuously (204) calculate a combined motion signal (148) from the radar system and the movement signal; and control (206) the magnetic resonance imaging system with the pulse sequence commands to acquire the magnetic resonance imaging data, wherein the acquisition of the magnetic resonance imaging data is controlled using the combined motion signal.

    ADMINISTRATION SYSTEM
    10.
    发明申请

    公开(公告)号:US20250050132A1

    公开(公告)日:2025-02-13

    申请号:US18729491

    申请日:2023-01-17

    Abstract: A mixture containing particles for use in a method of treating a tumor in an individual, wherein the mixture is administered by a system (1) for administration, the system comprising an administration subsystem (3) comprising at least one administration hydraulic element for containing a mixture with the particles, wherein the at least one administration hydraulic element is movably mounted for homogenizing the mixture, wherein said at least one administration hydraulic element is arranged for administering of the mixture, an actuation subsystem (2) comprising at least one actuation hydraulic element; wherein the at least one actuation hydraulic element is operably connected to the at least one administration hydraulic element for actuating said administration hydraulic element; wherein the at least one actuation hydraulic element is further fluidly connected with an operating element to operate the at least one actuation hydraulic element, wherein the actuation subsystem is hydraulically decoupled from the administration subsystem.

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