公开(公告)号：US20230124565A1

公开(公告)日：2023-04-20

申请号：US17800405

申请日：2021-02-05

申请人： PRESTIGE BIOPHARMA PTE LTD.

发明人： Jae Young YANG ,  Ji Sung PARK ,  Jae Ho SHIM ,  Yoon Joeng UM ,  Moon Jae LEE

IPC分类号： C07K16/06 ,  C07K1/18 ,  C07K16/24 ,  C07K1/34 ,  B01D15/36 ,  B01D15/32 ,  B01D15/42 ,  B01D15/18

摘要： The present invention relates to a method of preparing a population of antibodies, whereby a desired high-purity and high-quality population of antibodies can be prepared by removing impurities without using an expensive protein A column, and in particular, production costs can be significantly reduced while achieving process automation; and a population of antibodies prepared thereby.

公开(公告)号：US20230093889A1

公开(公告)日：2023-03-30

申请号：US17956291

申请日：2022-09-29

申请人： IFP Energies Nouvelles

发明人： Guillaume BLANCKE ,  Amir Hossein AHMADI-MOTLAGH ,  Alexandre VONNER ,  Mohamed DAHRAOUI ,  Ayoub ABOURICHA

IPC分类号： B01D15/18 ,  B01D15/20 ,  B01D15/42

摘要： Distribution and collection panel comprising an upper screen (4), a collector (5), a separation plate (6) with outlet openings (11), a distributor (7), a lower screen (8), an injection/withdrawal tank (9) adjacent to the separation plate, and a jet breaker element (12) perpendicular to the flow (E) of a main fluid and comprising two solid jet breaker plates (13) that are: extended on either side of the injection/withdrawal tank; juxtaposed with the lower screen; disposed beneath the outlet openings (11); designed to direct the main fluid in the distributor in a direction orthogonal to the direction of the flow (E), the ratio I/L of the width I of the solid jet breaker plate to the width L of the lateral part of the separation plate being at least 0.1.

公开(公告)号：US20230070693A1

公开(公告)日：2023-03-09

申请号：US17798399

申请日：2021-02-16

申请人： The General Hospital Corporation

发明人： Hakho Lee ,  Ralph Weissleder ,  Jan Van Deun

IPC分类号： B01D15/18 ,  G01N1/40 ,  B01D15/34 ,  B01D15/36 ,  B01D71/56 ,  B01D69/02 ,  B01D21/26 ,  B01D61/14

摘要： The present disclosure provides, in some embodiments, devices, methods, and kits for purifying extracellular vesicles (EVs) using size exclusion chromatography in tandem with cation exchange chromatography, which can be referred to as dual-mode chromatography (DMC).

公开(公告)号：US20230046104A1

公开(公告)日：2023-02-16

申请号：US16464356

申请日：2017-11-24

申请人： SAMYANG CORPORATION

发明人： Ji Won PARK ,  Sung Won PARK ,  Hye Jung KIM ,  Chong Jin PARK ,  Kang Pyo LEE

IPC分类号： C13K13/00 ,  C13K11/00 ,  B01D15/18 ,  B01D15/36 ,  B01D15/24

摘要： The present invention relates to a method for effectively utilizing fructose raffinate obtained in the process for separating psicose conversion product with a high purity chromatography in the process for preparing psicose, and more specifically, it is utilized for preparation of fructose-containing raw material solution for preparing psicose by supplying the fructose raffinate obtained in the separation step of psicose preparation into the psicose conversion reaction.

公开(公告)号：US11566043B2

公开(公告)日：2023-01-31

申请号：US17872326

申请日：2022-07-25

申请人： Mobius Biomedical, Inc.

发明人： Jason M. Criscione ,  Ali Ersen ,  John R. Linton ,  Sammy S. Datwani

IPC分类号： C07K1/36 ,  C07K16/00 ,  C07K1/34 ,  C07K1/22 ,  C07K1/26 ,  B01D69/10 ,  B01D15/38 ,  B01D57/02 ,  B01D15/20 ,  B01D15/18 ,  B01D71/68 ,  B01D63/10 ,  B01D69/02 ,  B01D69/14 ,  B01D59/10

摘要： Provided herein are, inter alia, biological manufacturing and downstream purification processes.

公开(公告)号：US20230016781A1

公开(公告)日：2023-01-19

申请号：US17374807

申请日：2021-07-13

申请人： BlueSky IP, LLC

发明人： Dimple K. Kundiyana ,  Nick Dokoozlian ,  Timothy Holt ,  Thomas Blair ,  Ravi Ponangi ,  Leah Chapin

IPC分类号： C12G1/02 ,  B01D15/18 ,  A23N1/00 ,  A23L2/04 ,  A23L2/10 ,  C13B20/14

摘要： This disclosure relates to a method and a system for processing grapes. An example system includes a simulated moving bed (SMB) device configured to receive a feed stream and an eluent stream as inputs and provide an extract stream and a raffinate stream as outputs. The feed stream includes a grape juice, the extract stream includes a high-sugar grape juice, and the raffinate stream includes a low-sugar grape juice. The system also includes fermentation equipment configured to produce a low-alcohol wine from the low-sugar grape juice.

公开(公告)号：US20230016539A1

公开(公告)日：2023-01-19

申请号：US17851293

申请日：2022-06-28

申请人： SHELL USA, INC.

发明人： Alan Anthony DEL PAGGIO ,  Wes W. Whitecotton ,  Christopher Rausch ,  Alexandra Ioana Sakamoto

IPC分类号： C10G1/00 ,  B01J20/18 ,  B01J20/08 ,  B01J20/04 ,  B01J20/02 ,  B01J20/28 ,  B01J20/34 ,  C10G1/10 ,  C10G69/06 ,  C10G61/06 ,  B01D15/18 ,  B01D15/20

摘要： A system for the treatment of a liquid plastic-derived oil having a pretreating section that includes a pretreating system having one or more reactors that may receive the liquid plastic-derived oil having one or more contaminants and a first contamination level. The one or more reactors includes a sorbent material having a faujasite (FAU) crystal framework type zeolitic molecular sieve and that may remove a first portion of the one or more contaminants from the liquid plastic-derived oil and generate a treated liquid plastic-derived oil having a second contamination level that is less than the first contamination level. The liquid plastic-derived oil is derived from a solid plastic waste (SPW), and the first portion of the one or more contaminants includes a halogen.

公开(公告)号：US20230008006A1

公开(公告)日：2023-01-12

申请号：US17947932

申请日：2022-09-19

申请人： Mobius Biomedical, Inc.

发明人： Jason M. Criscione ,  Ali Ersen ,  John R. Linton ,  Sammy S. Datwani

IPC分类号： C07K1/36 ,  C07K1/34 ,  C07K1/22 ,  C07K1/26 ,  B01D69/10 ,  B01D15/38 ,  B01D57/02 ,  B01D15/20 ,  B01D15/18 ,  B01D71/68 ,  B01D63/10 ,  B01D69/02 ,  B01D69/14 ,  C07K16/00 ,  B01D59/10

摘要： Provided herein are, inter alia, biological manufacturing and downstream purification processes.

公开(公告)号：US20220370696A1

公开(公告)日：2022-11-24

申请号：US17323081

申请日：2021-05-18

申请人： Medtronic, Inc.

发明人： Bryant J. Pudil ,  Mark David Schneider ,  Michael J. Elvidge

IPC分类号： A61M1/16 ,  B01J20/28 ,  B01J20/06 ,  B01J20/08 ,  B01J20/02 ,  B01J20/20 ,  B01J20/24 ,  B01J39/12 ,  B01J41/10 ,  A61M39/10 ,  B01D15/22 ,  B01D15/18

摘要： Sorbent cartridges having a flow control insert to improve the functional capacity of a sorbent cartridge is provided. Flow control inserts can include a plurality of flow channels filled with sorbent material through which fluid to be regenerated can travel in the sorbent cartridge.

公开(公告)号：US11498851B2

公开(公告)日：2022-11-15

申请号：US17837288

申请日：2022-06-10

申请人： Roy Kuennen

发明人： Roy Kuennen

IPC分类号： C02F1/00 ,  C02F1/76 ,  B01D29/15 ,  B01D35/26 ,  B01D35/28 ,  B01D35/30 ,  B01D15/12 ,  B01D15/14 ,  B01D15/18 ,  B01D15/10 ,  C02F1/28

摘要： A two-stage filtering system including a first and second filter container. The first filter container has a first filter assembly with a foam filter sleeve enveloping a fluid intake device, a connected valve, and transfer tubing. The second filter includes a pump connected to a spout, a second stage splashguard strainer, a second stage cup filter, and a second filter assembly. The second filter assembly includes at least one main filter comprising at least one carbon body filter enveloping a filter chamber, and exit tubing. The first filter container is structured to stack on top of the second filter container and the transfer tubing is structured to transfer first stage filtered fluid to the second filter container. The pump is structured to draw second stage filtered fluid from the second container through the exit tubing and expel the second stage filtered fluid out the spout to provide purified water.