公开(公告)号：US20240059443A1

公开(公告)日：2024-02-22

申请号：US18270932

申请日：2022-01-11

申请人： PHARMA INTEGRATION S.R.L.

发明人： Claudio BECHINI

IPC分类号： B65B43/46 ,  B65B31/00 ,  B65B3/00

CPC分类号： B65B43/46 ,  B65B31/00 ,  B65B3/003

摘要： A device (1) for moving a group of containers (A) for pharmaceutical or biotechnological use, between chambers (11, 12) with a controlled atmosphere comprising a support structure (7), supports (2) configured to accommodate containers (A) with an exposed part (B), a guide (3) for guiding the supports (2), rotationally coupled to the support structure (7), first rotating means (4) of the guide (3) and movement means (5) of the supports along the guide (3). The guide (3) rotates to locate the exposed parts (B) of the containers (A) in one of the chambers (11, 12) and the movement means (5) vary the distances (D) between the supports (2), preferably by means of a main body (51) which is rotationally coupled to the guide (3) and which comprises an external surface (52) on which tracks are formed (53, 54, 55, 56, 57, 58, 59, 60). Also described are an apparatus (100) and a method for producing pharmaceutical or biotechnological articles.

公开(公告)号：US11878829B2

公开(公告)日：2024-01-23

申请号：US18063980

申请日：2022-12-09

申请人： NEW SPS POD, LLC

发明人： Thomas M. McLenithan ,  Andrzej Kepinski ,  John Paselsky ,  Jeff Williams ,  Richard McKenzie ,  Richard Bishop

IPC分类号： B65B3/02 ,  B65B9/04 ,  B65B31/00 ,  B65B39/14 ,  B65B41/12 ,  B65B43/52 ,  B65B47/02 ,  B65B51/00 ,  B65B61/06 ,  B65D65/46 ,  C11D17/04

CPC分类号： B65B9/042 ,  B65B3/022 ,  B65B31/00 ,  B65B39/14 ,  B65B41/12 ,  B65B43/52 ,  B65B47/02 ,  B65B51/00 ,  B65B61/06 ,  B65D65/46 ,  C11D17/042 ,  C11D17/045

摘要： A packaging machine is provided for producing single and multiple compartment film wrapped pouches. Multiple linear motors allow aspects of the forming, filling, cutting and discharging to run at different speeds. The pouches are formed, filled and discharged from platens that are secured to movers that proceed through the packaging process by following magnetic fields created by independently controlled linear motors. Overall, cycle time is decreased as a result of speeding up parts of the process, including the platen return process, possible because there is no mechanical connection and not a single conveyor moving the platens while the other parts of the process may be simultaneously slowed down or even temporarily stopped. Changeover of platens, to accommodate different products, such as single compartment pouch to multiple compartment pouches, is also simplified because platens are simply connected to the movers and are thus easily removed and replaced.

公开(公告)号：US11753192B2

公开(公告)日：2023-09-12

申请号：US17972058

申请日：2022-10-24

申请人： Wisespray International Oy

发明人： Ilkka Parviainen ,  Marcus Weckman

IPC分类号： B65B3/12 ,  B65B31/00

CPC分类号： B65B3/12 ,  B65B31/003

摘要： Filling device for filling an aerosol container with a liquid, such as paint, which device comprises a cup for the liquid for the aerosol container, which cup is provided with an injection opening at its bottom surface; a piston for pushing the liquid from the cup via the injection opening to the aerosol container; and a piston head that is adapted to be detachably fixed on the end of the piston to be in contact with the liquid in the cup when the liquid is transferred from the cup to the aerosol container, which piston head is in the form of a scraper in continuous contact with the side wall of the cup during the liquid transferring operation, wherein the detachable fixing of the piston head allows the piston head to be withdrawn together with the piston from the cup after the liquid transferring operation is done.

公开(公告)号：US11731822B2

公开(公告)日：2023-08-22

申请号：US17470935

申请日：2021-09-09

申请人： A. RAYMOND ET CIE

发明人： Gaëtan Rey

IPC分类号： A61B50/33 ,  B65D77/00 ,  B65B5/06 ,  B65B7/28 ,  B65B31/00 ,  B65D25/10 ,  B65D81/20 ,  A61B50/00 ,  A61B50/30

CPC分类号： B65D77/003 ,  A61B50/33 ,  B65B5/068 ,  B65B7/2842 ,  B65B31/00 ,  B65D25/108 ,  B65D81/2015 ,  A61B2050/006 ,  A61B2050/3008 ,  A61B2050/314

摘要： A packaging system for medical containers having a main opening, comprising: a vessel having a shoulder; a tray provided with cavities that is intended for receiving a medical container and rests on the shoulder; a plurality of caps that close the main opening; and a lid that seals the vessel. A method for packaging medical containers, comprises the following steps: providing a vessel; arranging a tray on the shoulder of the vessel; arranging medical containers in the cavities; arranging a cap on the medical containers so as to close the main opening thereof; sealing a lid on an upper edge of the peripheral wall of the vessel; and placing the vessel in at least one sealed bag.

公开(公告)号：US20230052250A1

公开(公告)日：2023-02-16

申请号：US17976293

申请日：2022-10-28

申请人： Single Use Support GmbH

发明人： Thomas WURM

IPC分类号： B65B3/00 ,  B65B3/18 ,  B65B31/00

摘要： Method for filling a sterile container, in particular a bottle, with a liquid, wherein a sterile connection is established between a flexible bag and a first opening of the container, a sterile connection is established between a second opening of the container and a source of the liquid to be filled into the container, the liquid is filled into the container, a gas, in particular air, which is present in the container is displaced by the liquid and forced into the flexible bag while increasing the volume of the flexible bag and the connection between the source of liquid and the second opening of the container is severed in a sterile way.

公开(公告)号：US11576971B2

公开(公告)日：2023-02-14

申请号：US17350299

申请日：2021-06-17

申请人： Coherus Biosciences, Inc.

发明人： John Ogez ,  Jun Liu ,  Wenchang Ji ,  Patrick Daniel Begley ,  Isaias Prado ,  Mark Manning

IPC分类号： A61K39/39 ,  A61K39/395 ,  C07K16/24 ,  A61K47/18 ,  A61K9/08 ,  B65B31/00 ,  B65B7/28 ,  B65B3/00 ,  A61K47/02 ,  A61J1/06 ,  A61K9/00

摘要： The present invention is directed to methods for filling a container wherein the filled container has no headspace. The present invention is further directed to methods for stabilizing an aqueous drug substance solution by filling a container with the aqueous drug substance solution wherein the filled container has no headspace. The present invention is further directed to methods for detecting headspace in a container.

公开(公告)号：US11559712B2

公开(公告)日：2023-01-24

申请号：US16109055

申请日：2018-08-22

申请人： UTC Fire & Security Corporation

发明人： Henry Arnette

IPC分类号： A62C13/64 ,  B65B31/00 ,  A62C37/50

摘要： A portable fire extinguisher is disclosed which includes a cylinder for storing a pressurized fire extinguishing agent and has a neck portion defining an outlet, and a flexible hermetic seal supported across the outlet of the cylinder, wherein the flexible hermetic seal is adapted and configured to transition between: an unexpanded condition corresponding to an unpressurized cylinder; an expanded condition corresponding to a pressurized cylinder; and a bursted condition corresponding to an opened cylinder.

公开(公告)号：US20230016501A1

公开(公告)日：2023-01-19

申请号：US17951173

申请日：2022-09-23

申请人： Cryovac, LLC

发明人： Iacopo Tibe'

IPC分类号： B65B9/04 ,  B65B31/00 ,  B65B47/10 ,  B65B51/10 ,  B65B25/00

摘要： A process of packaging includes providing a bottom support, providing a top film, and forming a closed chamber where a portion of the bottom support, a product and a portion of the top film are housed. The further includes sealing the portion of the bottom support to the portion of the top film along a sealing band circumscribing the product to sealingly house the product in a volume and forming one or more hollow structures by sealing a part of the portion of the top film to a part of the portion of the bottom support at one or more selected seal zones. Before forming the hollow structure, the part of the portion of the top film and of the portion of the bottom support destined to form the hollow structure are maintained separate at a distance the one from the other.

公开(公告)号：US11534030B2

公开(公告)日：2022-12-27

申请号：US17002767

申请日：2020-08-25

申请人： W. Davis Lee ,  Warren R. Kirsch ,  Christian T. Metcalfe

发明人： W. Davis Lee ,  Warren R. Kirsch ,  Christian T. Metcalfe

IPC分类号： A47J43/12 ,  B65B31/00 ,  B65D83/14 ,  B65D83/42 ,  B65D83/28 ,  A23G3/52

摘要： The invention comprises a container apparatus and/or a method of manufacture thereof, comprising: a pressure containment housing containing both a first chemical and a second chemical; an interface configured to control dispersal of the first and second chemical out of the container; and a pressure within the container at time of manufacture exceeding ten bar. Generally, the mixture includes: (1) nitrous oxide as a gas, a liquid, a supercritical fluid, or a solid and (2) at least one of molecular hydrogen, helium, molecular nitrogen, carbon dioxide, neon, argon, krypton, and xenon in the form of a gas, liquid, supercritical fluid, or solid.

公开(公告)号：US11511896B2

公开(公告)日：2022-11-29

申请号：US16440617

申请日：2019-06-13

申请人： Multivac Sepp Haggenmüller SE & Co. KG

发明人： Michael Rädler ,  Florian Felch ,  Alexander Stötzner

IPC分类号： B65B31/00 ,  B65B9/02

摘要： A method for operating a sealing station of a packaging machine, wherein the method may include one or more of the following steps: filling a packing volume of a package with a gas to create a desired atmosphere to a preset gassing target pressure for a finished package, wherein the packaging volume may be defined by a lower and an upper packaging material; discharging a partial amount of the gas introduced into the packaging volume from the packaging volume into a collection volume while retaining the packaging volume generated by the preceding filling, which reduces the pressure within the packaging volume; and reducing the packaging volume by moving the upper packaging material to an end position that corresponds to a desired appearance such that the pressure inside the package increases again to near the gassing target pressure. A sealing station that performs this method is also described.