公开(公告)号：US20220281802A1

公开(公告)日：2022-09-08

申请号：US17631972

申请日：2020-07-31

申请人： Beth Israel Deaconess Medical Center, Inc.

发明人： Leena PRADHAN-NABZDYK ,  Lijun SUN ,  Philip LOGERFO ,  Finith JERNIGAN ,  Gabriel BIRANNE ,  Frank W. LOGERFO

IPC分类号： C07C211/45 ,  C07D249/18 ,  C07C279/18 ,  C07D401/04

摘要： Compounds, pharmaceutical compositions, and methods are disclosed for inhibiting interaction between IL18 and IL18R.

公开(公告)号：US11345867B2

公开(公告)日：2022-05-31

申请号：US17304815

申请日：2021-06-25

申请人： Saudi Arabian Oil Company

发明人： Muthukumar Nagu ,  Nayef M. Alanazi

IPC分类号： C10G7/10 ,  C10G75/02 ,  C07C211/45

摘要： Corrosion inhibitor compositions and methods for inhibiting corrosion on a metal surface exposed to a hydrocarbon fluid are provided. The corrosion inhibition compositions can include a corrosion inhibitor, such as 3-dimethylamino benzoic acid, 4-dimethylamino benzoic acid, or 2,5-dihydroxyterephthalic acid. The corrosion inhibitor composition can further comprise dimethyl sulfoxide, and heavy aromatic naphtha. The corrosion inhibitor composition can be phosphate-free and can inhibit naphthenic acid corrosion. In the methods, a corrosion inhibitor composition is added to the hydrocarbon fluid exposed to the metal surface to prevent or inhibit corrosion on the metal surface, including naphthenic acid corrosion.

公开(公告)号：US11084784B2

公开(公告)日：2021-08-10

申请号：US15128932

申请日：2015-03-25

申请人： PIRAMAL ENTERPRISES LIMITED

发明人： Rajiv Sharma ,  Bichismita Sahu ,  Sunil Vasantrao Mali ,  Deepak Singh ,  Pramod Bhaskar Kumar ,  Mahesh Dawange ,  Hitesh Mistry

IPC分类号： C07C317/32 ,  C07D311/22 ,  C07D335/06 ,  C07D265/36 ,  C07D207/27 ,  C07D295/26 ,  C07C233/29 ,  C07C237/22 ,  A61K31/18 ,  A61K31/351 ,  C07C217/88 ,  C07C317/24 ,  C07C311/08 ,  C07C255/46 ,  C07C233/54 ,  C07C217/48 ,  C07C211/45 ,  C07C215/70 ,  C07C255/50 ,  A61K31/277 ,  C07C309/89 ,  C07C225/22 ,  C07C229/42 ,  C07C317/44 ,  A61K31/165 ,  C07C323/09 ,  A61K31/5375 ,  C07C311/37 ,  C07F5/02 ,  A61K31/402 ,  C07D317/72 ,  C07C217/76 ,  C07C205/36 ,  A61K31/382 ,  C07F7/18 ,  C07C237/52 ,  C07C311/21 ,  C07C381/10 ,  C07D211/14 ,  C07D213/30 ,  C07D231/12 ,  C07D233/58 ,  C07D257/04 ,  C07D295/088 ,  C07D295/135 ,  C07D295/192 ,  C07D305/08

摘要： The present invention relates to a compound of formula I, or an isotopic form, stereoisomer, a tautomer, a pharmaceutically acceptable salt, a solvate, a polymorph, a prodrug, N-oxide or S-oxide thereof; and processes for their preparation. The invention further relates to pharmaceutical compositions containing the compounds and their use in the treatment of diseases or disorders mediated by RORγ.

公开(公告)号：US20200373495A1

公开(公告)日：2020-11-26

申请号：US16611520

申请日：2019-09-25

申请人： WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD.

发明人： Keyan BAI

IPC分类号： H01L51/00 ,  H01L27/32 ,  C07C211/45 ,  C07C209/68 ,  C09K11/06 ,  C07D209/86 ,  C07D209/88 ,  C07D219/02 ,  C07D235/18 ,  C07D249/08

摘要： The present application provides a blue fluorescent material and an OLED display panel, wherein the blue fluorescent material is a tetrahedral structure formed by simultaneously connecting a tert-butyl pyrene and a charge carrier transport unit to a same carbon of cyclohexane; wherein the tert-butyl pyrene increases an external quantum efficiency of the OLED display panel, and the tetrahedral structure increases distance between activated particles and reduces a concentration quenching. The charge carrier transport unit improves a balance of the carrier transfer and alleviates a problem that the current OLED display panel has a low luminous efficiency of the blue light material.

公开(公告)号：US20180111924A1

公开(公告)日：2018-04-26

申请号：US15843860

申请日：2017-12-15

申请人： DOW AGROSCIENCES LLC

发明人： Jeffery D. WEBSTER ,  Natalie C. GIAMPIETRO ,  David A. DEMETER ,  Thomas C. SPARKS

IPC分类号： C07D417/12 ,  A01N55/08 ,  A01N47/34 ,  A01N47/12 ,  A01N43/653 ,  A01N25/32 ,  A01N25/00 ,  A01N47/36 ,  C07F5/04 ,  C07D285/01 ,  C07D405/10 ,  A01N47/40 ,  C07C267/00 ,  C07C335/02 ,  C07C211/45 ,  C07D403/10 ,  C07D277/54 ,  C07C335/26

CPC分类号： C07D417/12 ,  A01N25/00 ,  A01N25/32 ,  A01N43/653 ,  A01N47/12 ,  A01N47/34 ,  A01N47/36 ,  A01N47/40 ,  A01N47/42 ,  A01N53/00 ,  A01N55/08 ,  C07C211/45 ,  C07C267/00 ,  C07C335/02 ,  C07C335/16 ,  C07C335/26 ,  C07D249/08 ,  C07D277/54 ,  C07D285/01 ,  C07D403/10 ,  C07D405/10 ,  C07F5/04

摘要： This disclosure relates to the field of molecules having pesticidal utility against pests in phyla Nematoda, Arthropoda, and/or Mollusca, processes to produce such molecules and intermediates used in such processes, compositions containing such molecules, and processes of using such molecules against such pests. These molecules may be used, for example, as nematicides, acaricides, insecticides, miticides, and/or molluscicides. This document discloses molecules having the following formula (“Formula One” and “Formula Two”).

公开(公告)号：US20180044332A1

公开(公告)日：2018-02-15

申请号：US15790183

申请日：2017-10-23

申请人： Dow AgroSciences LLC

发明人： Natalie C. Giampitro ,  Lindsey G. Fischer ,  Erich W. Baum ,  Gary D. Crouse ,  Andrew L. Ward ,  Thomas C. Sparks ,  Jeff Petkus

IPC分类号： C07D417/12 ,  A01N47/34 ,  A01N47/12 ,  A01N43/653 ,  A01N25/32 ,  A01N25/00 ,  A01N47/36 ,  C07C335/26 ,  C07D285/01 ,  C07D405/10 ,  A01N47/40 ,  C07C267/00 ,  C07C335/02 ,  C07C211/45 ,  C07D403/10 ,  C07D277/54 ,  A01N55/08 ,  C07F5/04

CPC分类号： C07D249/08 ,  A01N25/00 ,  A01N25/32 ,  A01N43/653 ,  A01N47/12 ,  A01N47/34 ,  A01N47/36 ,  A01N47/40 ,  A01N47/42 ,  A01N53/00 ,  A01N55/08 ,  C07C211/45 ,  C07C267/00 ,  C07C335/02 ,  C07C335/16 ,  C07C335/26 ,  C07D277/54 ,  C07D285/01 ,  C07D403/10 ,  C07D405/10 ,  C07D417/12 ,  C07F5/025 ,  C07F5/04

摘要： This disclosure relates to the field of molecules having pesticidal utility against pests in phyla Nematoda, Arthropoda, and/or Mollusca, processes to produce such molecules and intermediates used in such processes, compositions containing such molecules, and processes of using such molecules against such pests. These molecules may be used, for example, as nematicides, acaricides, insecticides, miticides, and/or molluscicides. This document discloses molecules having the following formula (“Formula One”).

公开(公告)号：US20170334819A1

公开(公告)日：2017-11-23

申请号：US15522838

申请日：2015-10-30

申请人： ORGANOFUEL SWEDEN AB

发明人： Armando CÓRDOVA ,  Samson AFEWERKI ,  Carlos PALO-NIETO

IPC分类号： C07C41/18 ,  C07C43/205 ,  C10L1/04 ,  C07C43/23 ,  C07C211/45 ,  C07C1/22 ,  C07C47/575 ,  C07C45/51 ,  C07C209/36 ,  C10L1/02

CPC分类号： C07C41/18 ,  C07C1/22 ,  C07C29/145 ,  C07C41/26 ,  C07C43/205 ,  C07C43/23 ,  C07C45/30 ,  C07C45/512 ,  C07C47/575 ,  C07C209/325 ,  C07C209/36 ,  C07C209/68 ,  C07C211/45 ,  C07C2521/08 ,  C07C2523/44 ,  C07C2531/12 ,  C10G3/45 ,  C10G3/47 ,  C10L1/02 ,  C10L1/04 ,  C10L2200/04 ,  Y02P20/52 ,  Y02P20/584 ,  Y02P30/20 ,  C07C43/2055 ,  C07C33/22 ,  C07C47/55 ,  C07C47/277 ,  C07C211/47 ,  C07C15/06 ,  C07C15/073 ,  C07C15/16 ,  C07C15/02

摘要： A method of reducing a C—O bond to the corresponding C—H bond in a substrate, which could be a benzylic alcohol, allylic alcohol, ester or an ether bond beta to a hydroxyl group or alpha to a carbonyl group using a recyclable metal catalyst system. The recyclable catalyst system is also applicable to reducing a C═O bond to the corresponding C—OH bond and then C—H bond. These methodologies can be linked in one-pot to selective oxidation and depolymerizations of aromatic polyols such as lignin.

公开(公告)号：US20170174582A1

公开(公告)日：2017-06-22

申请号：US15129282

申请日：2015-03-27

申请人： Dow Global Technologies LLC ,  Dow AgroSciences LLC

发明人： Patrick S. Hanley ,  Gregory T. Whiteker ,  Matthias S. Ober ,  William J. Kruper, Jr. ,  Arkady L. Krasovskiy

IPC分类号： C07C1/32 ,  C07B37/04 ,  C07D213/16 ,  C07C22/04 ,  C07C233/00 ,  C07C211/45 ,  C07C22/08 ,  C07C15/14 ,  C07D263/54

CPC分类号： C07C1/322 ,  C07B37/04 ,  C07C1/321 ,  C07C15/14 ,  C07C17/263 ,  C07C22/04 ,  C07C22/08 ,  C07C41/30 ,  C07C45/70 ,  C07C67/343 ,  C07C211/45 ,  C07C231/12 ,  C07C233/00 ,  C07C253/30 ,  C07C2531/22 ,  C07C2531/24 ,  C07C2531/28 ,  C07D213/127 ,  C07D213/16 ,  C07D263/54 ,  C07C233/65 ,  C07C255/50 ,  C07C43/205 ,  C07C49/784 ,  C07C69/76

摘要： In one aspect, there is provided a method of coupling a first aromatic compound having a fluorosulfonate substituent to a second aromatic compound having a boron-containing substituent. In another aspect, there is provided a method of coupling a first aromatic compound having a hydroxyl substituent to a second aromatic compound having a boron-containing substituent in a one-pot reaction.

公开(公告)号：US20160194577A1

公开(公告)日：2016-07-07

申请号：US14912273

申请日：2014-08-14

申请人： JX NIPPON OIL & ENERGY CORPORATION

发明人： Koji HOSHINO ,  Ryuichi UENO ,  Shinji HASEGAWA

IPC分类号： C10M169/04 ,  C10M133/24 ,  C10M129/70 ,  C07C69/78 ,  C07C211/45 ,  C07C69/34 ,  C07C255/50 ,  C07C255/54 ,  C07C39/06 ,  C10M105/02 ,  C07C69/22

CPC分类号： C10M169/04 ,  C07C39/06 ,  C07C69/22 ,  C07C69/34 ,  C07C69/78 ,  C07C211/45 ,  C07C255/50 ,  C07C255/54 ,  C10M105/02 ,  C10M129/70 ,  C10M129/72 ,  C10M129/74 ,  C10M129/76 ,  C10M133/04 ,  C10M133/16 ,  C10M133/24 ,  C10M135/00 ,  C10M2207/142 ,  C10M2207/283 ,  C10M2207/284 ,  C10M2207/285 ,  C10M2207/289 ,  C10M2215/04 ,  C10M2215/082 ,  C10M2215/16 ,  C10N2230/06 ,  C10N2230/56 ,  C10N2240/042 ,  C10N2240/045 ,  C10N2240/10

摘要： A lubricant additive including a compound represented by a general formula (1): (In the general formula (1), R is a hydrocarbon-containing, group having a carbon number of no less than 1; X1 is a single bond, —CONH— group, —NHCO— group, —NH— group, or a linking group having a carbon number of 0 to 1 and having no less than one heteroatom and not having a hydrogen atom bonded to the heteroatom; X2 is a single bond, or a linking group having a carbon number of 0 to 1 and having no less than one heteroatom and not having a hydrogen atom bonded to the heteroatom; Z is —CN group, —CO2CH3 group, or a group having a carbon number of 0 to 6 and having no less than one heteroatom and a hydrogen atom bonded to the heteroatom.).

摘要翻译： 一种润滑剂添加剂，其包含由通式（1）表示的化合物：（在通式（1）中，R是碳数不小于1的含烃基; X1是单键，-CONH - 基团，-NHCO-基团，-NH-基团或碳原子数为0〜1且具有不少于一个杂原子且不具有与该杂原子键合的氢原子的连接基团; X 2为单键，或 碳原子数为0〜1且不少于1个杂原子且不具有与该杂原子键合的氢原子的连接基团; Z为-CN基，-CO 2 CH 3基或碳数为0〜6的基团 并且具有不少于一个杂原子和与该杂原子键合的氢原子）。

公开(公告)号：US20140073500A1

公开(公告)日：2014-03-13

申请号：US14028130

申请日：2013-09-16

申请人： Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences

发明人： Yong Tang ,  Xiaohong Yang ,  Bo Liu ,  Xiuli Sun ,  Zhi Ma ,  Yuan Gao ,  Cong Wang

IPC分类号： C08F10/02 ,  C07D215/40 ,  C07D307/91 ,  C07C211/45

CPC分类号： C08F10/02 ,  C07C211/45 ,  C07C225/14 ,  C07C225/16 ,  C07C225/18 ,  C07C323/25 ,  C07C323/36 ,  C07C323/37 ,  C07C391/02 ,  C07D215/40 ,  C07D307/91 ,  C08F4/65912 ,  C08F10/00 ,  C08F110/02 ,  C08F210/16 ,  C08F4/6543 ,  C08F4/64127 ,  C08F2500/03 ,  C08F210/14 ,  C08F4/62124

摘要： Organic compounds containing heteroatoms and their use in preparing Ziegler-Natta(Ziegler-Natta) catalyst with single activation center. The Ziegler-Natta olefin polymerization catalyst is preparing by adding organic or inorganic solid carrier or compound of them which is pre-activated by heating or pre-treated chemically, organic compound containing heteroatoms and metallic compound into magnesium compound/tetrahydrofuran solution. The Ziegler-Natta olefin polymerization catalyst prepared in the present invention is fluidizable powder and can prepare ethene homopolymer and copolymer of controllable construction with high catalytic activity, during homo-polymerization and combined polymerization with alpha-olefin of C3˜C18 under action of catalyst promoter such as alkyl aluminum, alkyl aluminoxane, and so on.

摘要翻译： 含有杂原子的有机化合物及其用于制备具有单一活化中心的齐格勒 - 纳塔（齐格勒 - 纳塔）催化剂。 齐格勒 - 纳塔烯烃聚合催化剂是通过加入有机或无机固体载体或它们的化合物来制备的，它们通过将含有杂原子和金属化合物的化学有机化合物加热或预处理预活化成镁化合物/四氢呋喃溶液。 在本发明中制备的齐格勒 - 纳塔烯烃聚合催化剂是可流化粉末，并且可以在催化剂促进剂的作用下在均聚和与C3〜C18的α-烯烃的组合聚合期间制备具有高催化活性的可控构造的乙烯均聚物和共聚物 例如烷基铝，烷基铝氧烷等。