SYNTHESIS AND PURIFICATION OF CANNABIGEROL AND ITS APPLICATION

    公开(公告)号:US20220296482A1

    公开(公告)日:2022-09-22

    申请号:US17618111

    申请日:2019-06-11

    申请人: SYMRISE AG

    摘要: The present invention relates to a method for producing cannabigerol and purifying it from a reaction mixture. The present invention also relates to the cosmetic use of cannabigerol for the inhibition of tyrosinase activity and/or the reduction of melanin production in the skin, in particular for reducing pigmentation of the skin, preferably for the improvement of the appearance of the skin in case of hyperpigmentation, lentigo or vitiligo. Furthermore, the present invention relates to cannabigerol for use in a therapeutic method for the inhibition of tyrosinase activity and/or the reduction of melanin production in the skin, preferably for use in a therapeutic method for the treatment and/or prevention of malign skin disorders, in particular skin cancer.

    METHODS OF ISOLATING PHENOLS FROM PHENOL-CONTAINING MEDIA

    公开(公告)号:US20210061743A1

    公开(公告)日:2021-03-04

    申请号:US17003625

    申请日:2020-08-26

    IPC分类号: C07C37/86 C07C37/72 B01D11/04

    摘要: Methods of isolating phenols from phenol-containing media. The methods include combining a phospholipid-containing composition with the phenol-containing medium to generate a combined medium, incubating the combined medium to precipitate phenols in the combined medium and thereby form a phenol precipitate phase and a phenol-depleted phase, and separating the phenol precipitate phase and the phenol-depleted phase. The methods can further include extracting phenols from the separated phenol precipitate phase. The extracting can include mixing the separated phenol precipitate phase with an extraction solvent to solubilize in the extraction solvent at least a portion of the phenols originally present in the phenol precipitate phase.