Polyurethane excipient
    1.
    发明授权

    公开(公告)号:US12214041B2

    公开(公告)日:2025-02-04

    申请号:US17275729

    申请日:2019-09-16

    Abstract: In an embodiment, a polyurethane comprises the residues of i. an aliphatic diisocyanate, ii. an aliphatic diol comprising a poly(ethylene oxide) moiety, iii. an aliphatic diol comprising a polycarbonate moiety, and iv. a chain extender, wherein the polyurethane has a melting temperature of 140° C. or less and has a weight average molecular weight of from 100,000 to 500,000 g/mol. In an embodiment, the polyurethane is substantially devoid of catalyst. In an embodiment, the polyurethane is formed by reactive extrusion. In an embodiment, a medical device comprises the polyurethane and a bioactive agent. The medical devices, methods, and polyurethanes may exhibit benefits in end-product biostability, drug release profile, health and safety, and processing speed or reproducibility.

    HIGH-RESILIENCE PU SPRING SPONGE AND PREPARING METHOD THEREOF

    公开(公告)号:US20250018623A1

    公开(公告)日:2025-01-16

    申请号:US18351768

    申请日:2023-07-13

    Abstract: A high-resilience PU spring sponge and a preparing method thereof are provided. The high-resilience PU spring sponge includes a sponge main body and high-strength springs. A top portion of the sponge main body defines a sponge top surface. First grooves are defined on the sponge top surface. A bottom portion of the sponge main body defines a sponge bottom surface. Second grooves are uniformly defined on the sponge bottom surface. The preparing method includes a mold preheating and mold pretreatment step, a material mixing pretreatment step, a slurry introducing step, a slurry foaming curing and demolding step, and a natural curing and finished product processing step. The second grooves are defined on the sponge main body after the sponge main body is cured and the second grooves are formed through the perforated columns. Each of the first grooves is communicated with a corresponding second groove.

    A modified polyisocyanate
    10.
    发明公开

    公开(公告)号:US20240301122A1

    公开(公告)日:2024-09-12

    申请号:US18044460

    申请日:2021-09-29

    Abstract: The invention relates to a modified polyisocyanate and use thereof, especially as a crosslinking component in a water-soluble or water-dispersible coating composition. The modified polyisocyanate comprises iminooxadiazinedione structure and isocyanurate structure, wherein the weight ratio of the iminooxadiazinedione structure to the isocyanurate structure is not less than 1: 5; and relative to the total weight of the modified polyisocyanate, the total amount of molecules with a number average molecular weight greater than 2700 g/mol in the modified polyisocyanate is 4.1% by weight to 22% by weight; and the modified polyisocyanate is obtainable by the reaction of: an aminosulfonic acid, a polyisocyanate; a tertiary amine; and optionally a polyether alcohol containing ethylene oxide groups.

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