公开(公告)号：US20230140713A1

公开(公告)日：2023-05-04

申请号：US17905873

申请日：2021-03-19

申请人： SECRETARY OF STATE FOR HEALTH AND SOCIAL CARE ,  THE UNIVERSITY OF SOUTHAMPTON

发明人： John Mark Sutton ,  Charlotte Hind ,  Hywel Morgan ,  Daniel Spencer

IPC分类号： C12Q1/18 ,  G01N15/02 ,  G01N15/10

摘要： Methods are presented which use impedance flow cytometry for rapid susceptibility testing of antimicrobial agents including phage, antimicrobial peptides and rapid analysis of antimicrobial mediated serum bactericidal assays.

公开(公告)号：US20230140684A1

公开(公告)日：2023-05-04

申请号：US17914812

申请日：2021-03-16

申请人： J-Oil Mills, Inc.

发明人： Kenichi KAKIMOTO ,  Ryohei WATANABE ,  Masami INOUE

IPC分类号： G01N33/03

摘要： Provided is an edible oil deterioration level determination device and the like capable of precisely determining the deterioration level of frying oil. A deterioration level determination device 5 for determining the deterioration level of frying oil Y comprises an air bubble image extraction section 51 for extracting an air bubble image that is an image of a portion of air bubbles formed due to deep-fry cooking from an oil surface image, a feature parameter calculation section 54 for calculating a feature parameter F characterizing deterioration of the frying oil Y from the air bubble image extracted by the air bubble image extraction section 51, a deterioration indicator estimation section 55 for estimating a deterioration indicator DI of the frying oil Y based on the feature parameter F, and a deterioration level determination section 56 for determining the deterioration level of the frying oil Y based on the deterioration indicator DI.

公开(公告)号：US20230140545A1

公开(公告)日：2023-05-04

申请号：US17978429

申请日：2022-11-01

申请人： TDK CORPORATION

发明人： Mayumi TAKAHASHI ,  Kotaro TERAO ,  Raitaro MASAOKA

IPC分类号： G01N27/60 ,  G01N33/00

摘要： A gas sensor includes a quartz crystal unit and a sensitive layer formed on the quartz crystal unit and configured to adsorb a gas to be detected, wherein the sensitive layer is porous, and has a particle skeleton made of a plurality of conductive polymer particles and a polyelectrolyte that is at least partially disposed between the adjacent conductive polymer particles.

公开(公告)号：US20230140453A1

公开(公告)日：2023-05-04

申请号：US18052282

申请日：2022-11-03

申请人： KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  KOREA FOOD RESEARCH INSTITUTE

发明人： Eun Mi HWANG ,  Ajung KIM ,  Jaekwang LEE ,  Seoyoung JUNG

IPC分类号： G01N33/50

摘要： The present invention relates to obesity control by regulating the expression level of TREK1.

公开(公告)号：US20230140035A1

公开(公告)日：2023-05-04

申请号：US17935152

申请日：2022-09-26

申请人： Atreca, Inc.

发明人： Jeff DeFalco ,  Daniel Eric Emerling ,  Jessica Finn ,  Norman Michael Greenberg ,  Vera Huang ,  Shaun M. Lippow ,  Fengling Liu ,  Amy Manning-Bog ,  William H. Robinson ,  Alexander Scholz ,  Tito Serafini ,  Nikhil Vad ,  Wayne Volkmuth ,  Yann Chong TAN

IPC分类号： C07K16/30 ,  A61P35/00 ,  A61K39/395 ,  G01N33/68

摘要： Provided herein are antibodies that bind to tumor tissue through a binding interaction with an extracellular RNA-protein complex. Such antibodies are used in methods of inducing an immune response and methods of inhibiting tumor cell growth. Additionally provided are methods of producing such antibodies.

公开(公告)号：US20230139837A1

公开(公告)日：2023-05-04

申请号：US18069005

申请日：2022-12-20

申请人： Wisconsin Alumni Research Foundation

发明人： Ying GE ,  Song JIN ,  Tania GUARDADO ALVAREZ ,  Kyle BROWN

IPC分类号： G01N33/68 ,  C07C309/15

摘要： The present invention provides photo-cleavable anionic surfactants, particularly 4-hexylphenylazosulfonate (Azo) and sodium 4-hexylphenylazosulfonate derivatives, which can be rapidly degraded upon UV irradiation, for top-down and bottom-up proteomics. These surfactants can effectively solubilize proteins and peptide fragments with performance comparable to sodium dodecyl sulfate (SDS) and are compatible with mass spectrometry analysis of the solubilized proteins and peptide fragments. Top-down proteomic studies using the present photo-cleavable anionic surfactants has allowed the detection of 100-fold more unique proteoforms as compared to controls and has enabled the solubilization of membrane proteins for comprehensive characterization of protein post-translational modifications. In addition, the present photo-cleavable anionic surfactants are also suitable for dissolving polypeptides in bottom-up proteomic experiments including extracellular matrix proteomics, and are suitable as a substitute for SDS in gel electrophoresis.

公开(公告)号：US20230139694A1

公开(公告)日：2023-05-04

申请号：US17519351

申请日：2021-11-04

申请人： Instrumentation Laboratory Company

发明人： Demetrio Sanchez-Martinez ,  Joshua Shreve

IPC分类号： B01L3/00 ,  G01N1/28

摘要： Operations performed according to the example techniques described herein include controlling a probe to pierce a stopper of a container containing a substance, where the stopper provides an air-tight seal for the container, and where the air-tight seal supports an internal pressure in the container. The operations also include detecting the internal pressure based on information from a pressure sensor; determining that the internal pressure is not at a target pressure and, based on determining that the internal pressure is not at the target pressure, controlling the probe either to aspirate air from the container or to dispense air into the container in order to move the internal pressure toward the target pressure.

公开(公告)号：US20230139316A1

公开(公告)日：2023-05-04

申请号：US17550267

申请日：2021-12-14

申请人： Saudi Arabian Oil Company

发明人： Dwight W. Swett

IPC分类号： G01N21/3577 ,  G01N33/28

摘要： A miniature Fourier transform mid-infrared (FT-MIR) spectrometer is provided. The FT-MIR includes a metasurface IR source to emit radiation when heated, a microelectromechanical (MEMS) interferometer, and a metasurface microbolometer to measure an interferogram from the MEMS interferometer, wherein the miniature FT-MIR spectrometer is less than about 20 mm in outer diameter.

公开(公告)号：US20230139309A1

公开(公告)日：2023-05-04

申请号：US18090187

申请日：2022-12-28

申请人： W. D. Von Gonten Laboratories, LLC

发明人： Safdar Ali ,  Ashish Mathur ,  Chad Belanger

IPC分类号： G01N24/08 ,  G01N33/24 ,  G01R33/46 ,  G01R33/31 ,  G01R33/30

摘要： Methods for determining a volume of stored gas within a rock sample includes loading a rock sample into an overburden cell. A hydrocarbon gas at a gas pressure is applied to the rock sample and a confining fluid at a confining pressure is applied to the overburden cell. The confining pressure and the gas pressure are increased until a first pressure and temperature condition is met. With the rock sample maintained at the first temperature and pressure condition, a nuclear magnetic resonance spectrometer is used to scan the rock sample and measure a hydrocarbon gas volume within the rock sample. This measured hydrocarbon gas volume is then corrected using a Real Gas Index to determine the volume of stored gas within the rock sample.

公开(公告)号：US20230139301A1

公开(公告)日：2023-05-04

申请号：US17910927

申请日：2021-02-03

申请人： Hitachi High-Tech Corporation

发明人： Daisuke EBIHARA ,  Shinya MATSUOKA

IPC分类号： G01N35/10 ,  G01N35/00

摘要： To provide an automatic analyzer capable of relaxing the effect of a previously created mixed liquid when a new mixed liquid is created. An automatic analyzer according to the present disclosure: is configured so as to create a second mixed liquid after a first mixed liquid is created; and introduces a relaxation reagent to relax the effect of a first reagent remaining in a mixed liquid chamber when the second mixed liquid is created into the mixed liquid chamber on the basis of characteristics of the first mixed liquid.