公开(公告)号：US20240361244A1

公开(公告)日：2024-10-31

申请号：US18766095

申请日：2024-07-08

申请人： HAMAMATSU PHOTONICS K.K.

发明人： Tomonori NAKAMURA

IPC分类号： G01N21/64 ,  G01N21/01 ,  G01N21/62 ,  G01N21/63 ,  G01N21/88 ,  G01N21/95

CPC分类号： G01N21/6456 ,  G01N21/62 ,  G01N21/63 ,  G01N21/64 ,  G01N21/6458 ,  G01N21/6489 ,  G01N21/8806 ,  G01N21/8851 ,  G01N21/9501 ,  G01N21/9505 ,  G01N2021/0112 ,  G01N2021/6421 ,  G01N2021/6463 ,  G01N2021/6484 ,  G01N2021/8845

摘要： An inspection apparatus is an inspection apparatus for inspecting a sample on which a plurality of light-emitting elements is formed, and includes an excitation light source that generates excitation light to irradiate the sample, a camera that images fluorescence having a wavelength longer than a reference wavelength in fluorescence from the light-emitting elements, and a control apparatus that determines a quality of each of the light-emitting elements based on fluorescence imaged by the camera, in which the reference wavelength is a wavelength obtained by adding a full width at half maximum of a normal fluorescence spectrum of the light-emitting element to a peak wavelength of the normal fluorescence spectrum.

公开(公告)号：US12130227B2

公开(公告)日：2024-10-29

申请号：US17064775

申请日：2020-10-07

申请人： Excelitas Technologies Corp.

发明人： John Christopher Freitag ,  Theresa Thompson ,  Garth Eliason ,  Jay Pasquantonio

IPC分类号： G01N21/01 ,  A61L2/10 ,  C12M3/00 ,  G01N21/64 ,  B01L3/00 ,  B01L9/00 ,  C12M1/12 ,  G06V20/69

CPC分类号： G01N21/01 ,  A61L2/10 ,  B01L13/02 ,  C12M23/48 ,  B01L3/5085 ,  B01L9/523 ,  B01L2300/0829 ,  C12M37/00 ,  G01N2021/646 ,  G06V20/69

摘要： A system for irradiating a microplate may include a modular light engine with one or more light emitting devices. The light emitting devices are configured to emit germicidal radiation to irradiate the microplate, which is configured to be positioned below the modular light engine inside a chamber of the microplate irradiation system. In this way, a uniform intensity of germicidal radiation may be output by light emitting devices, resulting in disruption of contaminating nucleic acids present in the microplate.

公开(公告)号：US20240353349A1

公开(公告)日：2024-10-24

申请号：US18357572

申请日：2023-07-24

申请人： Nanjing University

发明人： Yixin Zhang ,  Shuai Tong ,  Xuping Zhang ,  Shaoxiong Tang ,  Ruofan Wang ,  Haoran Wang ,  Shun Wang ,  Feng Wang

IPC分类号： G01N21/95 ,  G01N21/01

CPC分类号： G01N21/95 ,  G01N21/01

摘要： A monitoring system and method for broken wires in PCCP based on distributed optical fiber sensing relates to the technical field of optical fiber sensing. The monitoring system for broken wires in PCCP comprises a Sagnac interferometer, a Φ-OTDR system, a dual loopback system and a signal processing system. The Sagnac interferometer comprises a first laser, a first optical coupler, a first delay optical fiber, a Faraday rotating mirror and a first photodetector. The Φ-OTDR system comprises a second laser, a second optical coupler, an acousto-optic modulator, a circulator, a third optical coupler and a second photodetector. The dual loopback system comprises a wavelength division multiplexer and a second delay optical fiber. The invention solves the problems of low positioning accuracy, limited frequency measurement range, detection dead zone and high computing pressure in monitoring broken wires in PCCP.

公开(公告)号：US12111247B2

公开(公告)日：2024-10-08

申请号：US17386229

申请日：2021-07-27

申请人： CUSTOM SENSORS & TECHNOLOGY

发明人： Richard Nordman ,  Mike Ponstingl

IPC分类号： G01N21/01

CPC分类号： G01N21/01

摘要： A flow cell and flow cell system which allows for calibration of an attached sensor to be performed in place. Specifically, the ability to utilize standard addition techniques of calibration without the need to take a test sample from the process stream or remove the sensor from operating on the flow cell.

公开(公告)号：US20240319100A1

公开(公告)日：2024-09-26

申请号：US18574659

申请日：2021-10-20

申请人： TIANJIN UNIVERSITY ,  CIVIL AVIATION UNIVERSITY OF CHINA

发明人： Guanyi CHEN ,  Jian LI ,  Da CHEN ,  Beibei YAN ,  Junyu TAO ,  Wei ZHANG ,  Zhanjun CHENG ,  Shengquan ZHOU

IPC分类号： G01N21/65 ,  G01N1/34 ,  G01N21/01

CPC分类号： G01N21/65 ,  G01N1/34 ,  G01N21/01 ,  G01N2021/0112

摘要： The system includes a dust collector, a pressure controller, a dryer, a gas heat-insulation device, a gas pool, a gas detector, an optical monitor and a computer sequentially connected. The dust collector is used to filter solid particles in a gas. The pressure controller is used to control a flow rate of the gas. The dryer is used to control a humidity of the gas. The gas heat-insulation device is used to control a temperature of the gas. The gas pool is used to carry the gas. The laser is used to irradiate the gas in the gas pool to generate a Raman scattering light. The gas detector is used to collect the Raman scattering light. The optical monitor is used to adjust and amplify a light signal of the Raman scattering light. The computer is used to output a Raman spectrum and a composition and content of a tar.

公开(公告)号：US20240319068A1

公开(公告)日：2024-09-26

申请号：US18732356

申请日：2024-06-03

申请人： SEOUL VIOSYS CO., LTD.

发明人： Hee Ho BAE ,  Yeong Min YOON ,  A Young LEE

IPC分类号： G01N15/1429 ,  G01N1/30 ,  G01N15/00 ,  G01N15/01 ,  G01N15/1434 ,  G01N21/01 ,  G01N21/33 ,  G01N21/64 ,  G01N27/447 ,  G01N33/49

CPC分类号： G01N15/1429 ,  G01N1/30 ,  G01N15/00 ,  G01N15/1436 ,  G01N21/01 ,  G01N21/33 ,  G01N27/447 ,  G01N27/44721 ,  G01N33/49 ,  G01N33/491 ,  G01N15/01 ,  G01N2021/0112 ,  G01N21/6428 ,  G01N21/6486

摘要： A light irradiation device including an injection unit to inject a sample, and a light source to apply light to the sample to identify an abnormal cell in the sample, the light source including a substrate and a light emitter including a light emitting diode, in which the light emitted is to cut a genetic material in the sample into sections of different sizes, and to deform the genetic material to different degrees, such that a determination of an abnormality of the sample is based on the degree of deformation, and an irradiation amount or intensity of the light is at an intensity in which a cytotoxicity value of the sample is greater than or equal to a predetermined value, and a ratio of a degree of deformation of the genetic material of the normal sample to that of the abnormal sample is set to be a minimum value.

公开(公告)号：US20240303980A1

公开(公告)日：2024-09-12

申请号：US18511920

申请日：2023-11-16

申请人： The University of Tokyo ,  Osaka University

发明人： Sadao Ota ,  Issei Sato ,  Katsuhito Fujiu ,  Satoko Yamaguchi ,  Kayo Waki ,  Yoko Itahashi ,  Ryoichi Horisaki

IPC分类号： G06V10/82 ,  C12M1/34 ,  G01N15/10 ,  G01N15/14 ,  G01N15/1404 ,  G01N15/1429 ,  G01N15/1434 ,  G01N21/01 ,  G01N21/27 ,  G01N21/64 ,  G01N21/65 ,  G06F18/21 ,  G06F18/28 ,  G06V10/772 ,  G06V10/778 ,  G06V20/69

CPC分类号： G06V10/82 ,  C12M1/34 ,  G01N15/14 ,  G01N15/1404 ,  G01N15/1429 ,  G01N15/1434 ,  G01N15/1459 ,  G01N15/147 ,  G01N21/01 ,  G01N21/27 ,  G01N21/64 ,  G01N21/65 ,  G06F18/2178 ,  G06F18/28 ,  G06V10/772 ,  G06V10/7784 ,  G06V20/698 ,  G01N2015/1006 ,  G01N2015/1413 ,  G01N2015/1415 ,  G01N2015/145 ,  G06F2218/12

摘要： An analysis device includes an analysis unit configured to receive scattered light, transmitted light, fluorescence, or electromagnetic waves from an observed object located in a light irradiation region light-irradiated from a light source and analyze the observed object on the basis of a signal extracted on the basis of a time axis of an electrical signal output from a light-receiving unit configured to convert the received light or electromagnetic waves into the electrical signal.

公开(公告)号：US20240302270A1

公开(公告)日：2024-09-12

申请号：US18573276

申请日：2022-06-23

申请人： Clearstream Technologies Limited

发明人： Christopher Norris ,  Prathamesh Sharad Dhanpalwar ,  Luke Bernard Anthony Myles

IPC分类号： G01N21/31 ,  G01N21/01 ,  G01N21/35

CPC分类号： G01N21/314 ,  G01N21/01 ,  G01N21/35 ,  G01N2021/3181

摘要： A system for identifying a biological sample in a sample holder. The system comprising a light source for emitting substantially monochrome light directed at the sample holder; a light sensor for detecting the amount of light reflected or transmitted by the biological sample and 5 configured to output measurements indicative of the amount of light detected; and a controller connected to the light sensor and configured to identify the biological sample based on the output measurements of the light sensor.

公开(公告)号：US20240287497A1

公开(公告)日：2024-08-29

申请号：US18649451

申请日：2024-04-29

申请人： Nutcracker Therapeutics, Inc.

发明人： Benjamin Eldridge ,  Ximiao Wen

IPC分类号： C12N15/10 ,  B01J19/00 ,  B01L3/00 ,  C12M1/36 ,  G01N21/01

CPC分类号： C12N15/101 ,  B01J19/0046 ,  B01J19/0093 ,  B01L3/502769 ,  C12M41/48 ,  G01N21/01 ,  B01J2219/00313 ,  B01J2219/00333 ,  B01J2219/00722 ,  B01J2219/00759 ,  B01L2400/0487 ,  G01N2021/0187

摘要： Apparatuses and methods are described herein for processing polynucleotides in a sealed path environment. The apparatuses include optical sensors to monitor operations and to track material usage for good manufacturing practice.

公开(公告)号：US20240280485A1

公开(公告)日：2024-08-22

申请号：US18571316

申请日：2022-06-15

申请人： HITACHI HIGH-TECH CORPORATION

发明人： Takahiro Ando ,  Yasuhiro Keta ,  Yuya Matsuoka ,  Shohei Arita

IPC分类号： G01N21/59 ,  G01N21/01 ,  G01N35/02 ,  H01L25/16

CPC分类号： G01N21/59 ,  G01N21/01 ,  H01L25/167 ,  G01N35/025

摘要： There is provided a light source and an automatic analyzer, which stabilize an amount of light while covering a wide wavelength band used in the automatic analyzer.
The light source of the present invention includes a substrate, a first LED provided on the substrate, and a phosphor that converts an excitation light of the first LED into a broadband light, in which the temperature sensor is embedded in the phosphor together with the first LED. Further, the automatic analyzer of the present invention includes an absorbance measuring unit having this light source, and a reaction disk on which a reaction vessel for containing a reaction solution measured by the absorbance measuring unit is mounted.