ANALYTE SENSOR AND METHOD OF USE
    3.
    发明申请

    公开(公告)号:US20210003499A1

    公开(公告)日:2021-01-07

    申请号:US17023851

    申请日:2020-09-17

    IPC分类号: G01N21/03 G01N21/05 G01N21/62

    摘要: A sensor for isolating, identifying, and quantifying one or more analytes in a sample is provided, the sensor having a metal substrate base and a polymer waveguide disposed on the metal substrate base, the polymer waveguide including an optical channel and a polymer disposed in the optical channel; wherein the polymer waveguide optically couples a first and a second fiber optic cable. Also provided herein are methods of using the sensor for isolating, identifying, and quantifying one or more analytes in a sample, the method including contacting the polymer waveguide with a sample, sequentially heating the sensor to a plurality of temperature thresholds, obtaining an optical output at each temperature threshold, and analyzing differences in sequentially-obtained optical outputs in order to identify and determine concentrations of individual analytes of interest in the sample.

    Systems and methods for testing for a gas leak through a gas flow component

    公开(公告)号:US10408763B2

    公开(公告)日:2019-09-10

    申请号:US15545974

    申请日:2016-01-29

    发明人: Yves Gamache

    摘要: Methods and systems of testing for a gas leak between an inlet zone and an outlet zone of a gas flow component in a shut state are provided. Different tracer and carrier gases are used. The carrier gas is circulated through the outlet zone of the gas flow component to purge the tracer gas from this outlet zone. A spectroscopic emission from the carrier gas indicative of an amount of the purged tracer gas is monitored. A test flow of the tracer gas is introduced in the inlet zone of the gas flow component, and the inlet pressure is increased for successive pressure increments. The presence of a gas leak is determined upon detecting an intensity step variation in the monitored spectroscopic emission following one of the pressure increments in the inlet pressure.

    ANALYTE SENSOR AND METHOD OF USE
    7.
    发明申请

    公开(公告)号:US20190086322A1

    公开(公告)日:2019-03-21

    申请号:US15932299

    申请日:2016-08-18

    IPC分类号: G01N21/03 G01N21/05 G01N21/62

    摘要: A sensor for isolating, identifying, and quantifying one or more analytes in a sample is provided, the sensor having a metal substrate base and a polymer waveguide disposed on the metal substrate base, the polymer waveguide including an optical channel and a polymer disposed in the optical channel; wherein the polymer waveguide optically couples a first and a second fiber optic cable. Also provided herein are methods of using the sensor for isolating, identifying, and quantifying one or more analytes in a sample, the method including contacting the polymer waveguide with a sample, sequentially heating the sensor to a plurality of temperature thresholds, obtaining an optical output at each temperature threshold, and analyzing differences in sequentially-obtained optical outputs in order to identify and determine concentrations of individual analytes of interest in the sample.

    Microfluidic cartridge
    8.
    发明授权

    公开(公告)号:US10065185B2

    公开(公告)日:2018-09-04

    申请号:US14996670

    申请日:2016-01-15

    申请人: HandyLab, Inc.

    发明人: Kalyan Handique

    摘要: The technology described herein generally relates to microfluidic cartridges configured to amplify and detect polynucleotides extracted from multiple biological samples in parallel. The technology includes a microfluidic substrate, comprising: a plurality of sample lanes, wherein each of the plurality of sample lanes comprises a microfluidic network having, in fluid communication with one another: an inlet; a first valve and a second valve; a first channel leading from the inlet, via the first valve, to a reaction chamber; and a second channel leading from the reaction chamber, via the second valve, to a vent.