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公开(公告)号:US12237083B2
公开(公告)日:2025-02-25
申请号:US17593845
申请日:2021-06-14
Applicant: Bragg Analytics, Inc.
Inventor: Pavel Lazarev , Alexander Lazarev
IPC: G16H50/20 , A61B5/00 , G01N23/20 , G01N23/201 , G01N33/483 , G06F21/60 , G06N3/08 , G06Q20/08 , G06Q20/32 , G16H10/40 , G16H10/60 , G16H30/20 , G16H40/63 , G16H40/67
Abstract: Provided herein are diffractometer-based global diagnostic systems and uses thereof. The systems may comprise one or more diffraction apparatus operatively coupled to a computer database over a network. The one or more diffraction apparatus may be configured for transfer of data such as pathology lab image data, diffraction pattern data, subject data, or any combination thereof to the computer database over the network. The systems may further comprise one or more computer processors operatively coupled to the one or more diffraction apparatus, which computer processors may be configured to receive the data from the diffraction apparatus, transmit the data to the computer database, and process the data using a data analytics algorithm which may provide a computer-aided diagnostic indicator for the individual subject.
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公开(公告)号:US12181427B1
公开(公告)日:2024-12-31
申请号:US18722957
申请日:2022-12-13
Applicant: THE NOTTINGHAM TRENT UNIVERSITY , CRANFIELD UNIVERSITY
Inventor: Paul Evans , Keith Rogers
IPC: G01N23/20008 , G01N23/04 , G01N23/083 , G01N23/20
Abstract: A sample inspection system (100) includes an X-ray emitter, a collimator (170) and a first energy resolving detector (180) arranged along a symmetry axis (105). The X-ray emitter generates at least one focused conical shell beam (150) of X-ray radiation comprised of X-ray photons that propagate through a focal point on the symmetry axis downstream of the X-ray emitter. The collimator (170) has one or more channels, each channel being adapted to receive diffracted or scattered radiation propagating either along the symmetry axis, or parallel with the symmetry axis, or both along and parallel with the symmetry axis (105). Upon incidence of the conical shell beam (150) onto a sample (106) the first energy resolving detector (180) detects radiation diffracted or scattered by the sample (106) via the collimator (170).
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公开(公告)号:US20240418658A1
公开(公告)日:2024-12-19
申请号:US18722957
申请日:2022-12-13
Applicant: THE NOTTINGHAM TRENT UNIVERSITY , CRANFIELD UNIVERSITY
Inventor: Paul EVANS , Keith ROGERS
IPC: G01N23/20008 , G01N23/04 , G01N23/083 , G01N23/20
Abstract: A sample inspection system (100) includes an X-ray emitter, a collimator (170) and a first energy resolving detector (180) arranged along a symmetry axis (105). The X-ray emitter generates at least one focused conical shell beam (150) of X-ray radiation comprised of X-ray photons that propagate through a focal point on the symmetry axis downstream of the X-ray emitter. The collimator (170) has one or more channels, each channel being adapted to receive diffracted or scattered radiation propagating either along the symmetry axis, or parallel with the symmetry axis, or both along and parallel with the symmetry axis (105). Upon incidence of the conical shell beam (150) onto a sample (106) the first energy resolving detector (180) detects radiation diffracted or scattered by the sample (106) via the collimator (170).
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公开(公告)号:US12146844B2
公开(公告)日:2024-11-19
申请号:US17868283
申请日:2022-07-19
Applicant: TOYOTA JIDOSHA KABUSHIKI KAISHA
Inventor: Masaki Adachi
Abstract: A system of collating a spectral data of an arbitrary material with spectral data of existing materials to identify the kind of the arbitrary material comprises a one-dimensional CNN processor calculating a characteristic value vector based on a spectral data of a material by a one-dimensional convolution neural network algorithm, and a metric learning processor computing a probability that the kind of the material is each kind of the existing materials from the characteristic value vector by a deep metric learning algorithm. The processors learn with the spectral data of existing materials to compute a probability for the kind of each material such that the probabilities for the kinds of the respective materials inputted for data for learning becomes maximum. When the data of the arbitrary material is inputted, the kind giving the maximum probability is identified as the kind of the arbitrary material with high precision.
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公开(公告)号:US12065929B2
公开(公告)日:2024-08-20
申请号:US17647814
申请日:2022-01-12
Applicant: Saudi Arabian Oil Company
Inventor: Ferney Geovany Moreno Sierra , Ahmad Azly Bin Abdul Aziz , Neil W. Craigie , Faisal S. Al Reshedan , Nawaf Aldossary
IPC: E21B7/04 , E21B44/00 , G01N23/20 , G01N23/223 , G01N33/24
CPC classification number: E21B7/04 , E21B44/00 , G01N23/20 , G01N23/223 , G01N33/24 , E21B2200/20 , G01N2223/05 , G01N2223/076 , G01N2223/616
Abstract: A system and methods for petro-steering methodologies are provided. An exemplary method obtains rock fabric data, and integrate rock fabric data with dynamic productivity data to identify patterns between the rock fabric data and dynamic productivity data. Gas rates and steering values are predicted across UBCT wells based on the patterns.
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公开(公告)号:US12017216B2
公开(公告)日:2024-06-25
申请号:US17141786
申请日:2021-01-05
Applicant: Roche Diagnostics Operations, Inc.
Inventor: Andreas Drechsler , Darko Klinec , Michael Koehler , Alexander Jakob , Michael Zeder
IPC: B01L3/00 , G01F23/284 , G01F23/292 , G01F23/80 , G01N23/20 , G01N23/20091 , G01N35/00 , G01N21/3577 , G01N21/3581
CPC classification number: B01L3/502715 , G01F23/284 , G01F23/292 , G01F23/804 , G01N23/20091 , G01N35/00732 , B01L2300/1861 , G01N21/3577 , G01N21/3581
Abstract: A method to process a laboratory carrier in a laboratory system based on a feature of a test liquid in the laboratory carrier is presented. The laboratory system comprises the laboratory carrier comprising the test liquid, a terahertz wave source, a terahertz detector, a laboratory carrier processing device, and a control unit. Using terahertz technology and data analysis, the feature of the test liquid in the laboratory carrier can be determined. In addition, the control unit controls the laboratory carrier processing device based on the determined feature of the test liquid.
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7.
公开(公告)号:US20240103013A1
公开(公告)日:2024-03-28
申请号:US18359483
申请日:2023-07-26
Applicant: VIB VZW , Vrije Universiteit Brussel , The Board of Trustees of the Leland Stanford Junior University
Inventor: Jan Steyaert , Els Pardon , Soren G.F. Rasmussen , Juan Jose Fung , Brian Kobilka , Toon Laeremans
IPC: G01N33/68 , C07K14/705 , C07K14/72 , C07K16/28 , G01N23/20 , G01N33/566
CPC classification number: G01N33/6872 , C07K14/705 , C07K14/723 , C07K16/28 , G01N23/20 , G01N33/566 , G01N33/68 , G01N33/6857 , A61K38/00
Abstract: The present invention relates to the field of GPCR structure biology and signaling. In particular, the present invention relates to protein binding domains directed against or capable of specifically binding to a functional conformational state of a G-protein-coupled receptor (GPCR). More specifically, the present invention provides protein binding domains that are capable of increasing the stability of a functional conformational state of a GPCR, in particular, increasing the stability of a GPCR in its active conformational state. The protein binding domains of the present invention can be used as a tool for the structural and functional characterization of G-protein-coupled receptors bound to various natural and synthetic ligands, as well as for screening and drug discovery efforts targeting GPCRs. Moreover, the invention also encompasses the diagnostic, prognostic and therapeutic usefulness of these protein binding domains for GPCR-related diseases.
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公开(公告)号:US11940757B2
公开(公告)日:2024-03-26
申请号:US17353943
申请日:2021-06-22
Applicant: Accelerate Diagnostics, Inc.
Inventor: Oleg Gusyatin
IPC: G03H1/10 , C12M1/34 , G01N15/02 , G01N15/0227 , G01N15/10 , G01N15/14 , G01N15/1434 , G01N23/20 , G02B21/00 , G02B21/36 , G03H1/00 , G03H1/04 , G03H1/08 , G03H1/26
CPC classification number: G03H1/10 , C12M41/36 , G01N15/0227 , G01N15/1434 , G01N15/1475 , G01N23/20 , G02B21/0008 , G02B21/365 , G03H1/0443 , G01N2015/0233 , G01N2015/1006 , G01N2015/1454 , G01N2015/1493 , G01N2015/1497 , G03H2001/0033 , G03H2001/0447 , G03H1/0866 , G03H2001/2655 , G03H2222/13 , G03H2222/52 , G03H2226/13 , G03H2227/03
Abstract: Disclosed are optical interrogation apparatus that can produce lens-free images using an optoelectronic sensor array to generate a holographic image of sample objects, such as microorganisms in a sample. Also disclosed are methods of detecting and/or identifying microorganisms in a biological sample, such as microorganisms present in low levels. Also disclosed are methods of using systems to detect microorganisms in a biological sample, such as microorganisms present in low levels. In addition or as an alternative, the methods of using systems may identify microorganisms present in a sample and/or determine antimicrobial susceptibility of such microorganisms.
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公开(公告)号:US11927549B2
公开(公告)日:2024-03-12
申请号:US17470183
申请日:2021-09-09
Applicant: KLA Corporation
Inventor: Qian Zhang , Wayne Chiwoei Lo , Joseph Maurino , Tomas Plettner
IPC: G01N23/20 , G01N23/20008 , H01F7/02 , H05K9/00
CPC classification number: G01N23/20008 , H01F7/0273 , H05K9/0075 , G01N2223/052 , G01N2223/20 , G01N2223/30
Abstract: The present disclosure provides an inspection system and a method of stray field mitigation. The system includes an array of electron beam columns, a first permanent magnet array, and a plurality of shielding plates. The array of electron beam columns each includes an electron source configured to emit electrons toward a stage. The first permanent magnet array is configured to condense the electrons from each electron source into an array of electron beams. The first permanent magnet array is arranged at a first end of the array of electron beam columns. The plurality of shielding plates extend across the array electron beam columns downstream of the first permanent magnet array in a direction of electron emission. The array of electron beams pass through a plurality of apertures in each of the plurality of shielding plates, which reduces stray magnetic field in a radial direction of the array of electron beams.
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公开(公告)号:US11913890B1
公开(公告)日:2024-02-27
申请号:US18281237
申请日:2022-01-06
Applicant: Halo X Ray Technologies Limited
Inventor: Anthony Dicken , Daniel Spence
IPC: G01N23/10 , G01N23/044 , G01N23/087 , G01N23/20 , G01N23/20008 , G01N23/20091 , G01N23/205 , G01N23/2055
CPC classification number: G01N23/10 , G01N23/044 , G01N23/087 , G01N23/20008 , G01N23/20083 , G01N23/20091 , G01N23/205 , G01N23/2055 , G01N2223/045 , G01N2223/0561 , G01N2223/0563 , G01N2223/0566 , G01N2223/1016 , G01N2223/316 , G01N2223/3306 , G01N2223/401 , G01N2223/402 , G01N2223/403 , G01N2223/41 , G01N2223/419 , G01N2223/421 , G01N2223/423 , G01N2223/639
Abstract: There is presented a screening system and a corresponding method for screening an item. The screening system includes a detection apparatus (100), a rotatable platform (310) to receive the item, and a mechanical arrangement (320, 330). The detection apparatus has an emitter portion to generate a primary beam of ionising radiation and a detector portion to detect an absorption signal and at least one of a diffraction signal and a scattering signal. The mechanical arrangement is adapted to translate the detection apparatus along a translation axis to scan the item with the primary beam. The screening system may be used for identifying restricted or illicit substances that may be present in some luggage or in mail.
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