公开(公告)号：WO2017011685A1

公开(公告)日：2017-01-19

申请号：PCT/US2016/042330

申请日：2016-07-14

Applicant: CELATOR PHARMACEUTICALS, INC.

Inventor： WAN, Leon ,  LUI, Winnie ,  TARDI, Paul ,  MAYER, Lawrence

IPC: A61K9/00

CPC classification number: A61K9/5192 ,  A61K9/0019 ,  A61K9/5153 ,  A61K47/554

Abstract: Nanopaiticle compositions described herein comprise combinations of prodrugs of therapeutic agents that achieve enhanced therapeutic effects as compared to those observed when combinations of free forms of these therapeutic agents are administered.

Abstract translation: 本文所述的纳米微粒组合物包含与施用这些治疗剂的游离形式的组合时观察到的效果相比增强的治疗效果的治疗剂前药的组合。

公开(公告)号：WO2020123481A1

公开(公告)日：2020-06-18

申请号：PCT/US2019/065440

申请日：2019-12-10

Applicant: CELATOR PHARMACEUTICALS INC.

Inventor： HUMPHREYS, Robin ,  TARDI, Paul ,  WAN, Leon ,  LIBOIRON, Barry

IPC: A61K9/00 ,  A61K9/14 ,  A61K9/51 ,  A61K31/337 ,  A61K47/34

Abstract: The invention relates to compositions and methods for improved delivery of combinations of therapeutic agents. More particularly, the invention concerns delivery systems which provide combinations of taxanes and mTOR inhibitors and derivatives thereof as well as methods of treating cancer using the same.

公开(公告)号：WO2023288103A1

公开(公告)日：2023-01-19

申请号：PCT/US2022/037374

申请日：2022-07-15

Applicant: CELATOR PHARMACEUTICALS, INC.

Inventor： TARDI, Paul ,  WAN, Leon ,  GARG, Shyam Madhusudan ,  GAO, Jun ,  LEGROS, Philippe

IPC: A61K9/127 ,  A61K9/10 ,  A61K9/00 ,  A61K31/00

Abstract: Provided herein are methods of purifying liposomal formulations by washing with acidic aqueous solutions.

公开(公告)号：WO2023288100A1

公开(公告)日：2023-01-19

申请号：PCT/US2022/037371

申请日：2022-07-15

Applicant: CELATOR PHARMACEUTICALS, INC.

Inventor： TARDI, Paul ,  WAN, Leon ,  GARG, Shyam Madhusudan ,  GAO, Jun ,  LEGROS, Philippe

IPC: A61K9/127 ,  A61K9/10 ,  A61K31/015 ,  A61K47/6911 ,  A61K31/00

Abstract: Provided herein are liposomes comprising B-cell lymphoma (Bel) protein inhibitors, compositions comprising such liposomes, and methods using such formulations for treating hyperproliferative disorders.