专利检索 ap:("THE REGENTS OF THE UNIVERSITY OF MICHIGAN") AND inv:"ROLLAND, Delphine" 第 1 页

1.

发明申请
RECURRENT GENE FUSIONS IN CUTANEOUS CD30-POSITIVE LYMPHOPROLIFERATIVE DISORDERS 审中-公开
标题翻译：无性系CD30阳性淋巴细胞性贫血的基因融合

公开(公告)号：WO2016123517A2

公开(公告)日：2016-08-04

申请号：PCT/US2016/015714

申请日：2016-01-29

申请人： THE REGENTS OF THE UNIVERSITY OF MICHIGAN

发明人： ELENITOBA-JOHNSON, Kojo , KIEL, Mark J. , ROLLAND, Delphine , BETZ, Bryan L. , BAILEY, Nathanael G. , VELUSAMY, Thirunavukkarasu , LIM, Megan

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6886 , C12Q2600/112 , C12Q2600/156

摘要： Provided herein are kits, compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to recurrent gene fusions (e.g., recurrent translocations involving TYK2) as diagnostic markers and clinical targets for cutaneous CD30-positive lymphoproliferative disorders (e.g., lymphomatoid papulosis; primary cutaneous anaplastic large cell lymphoma).

摘要翻译： 本文提供用于癌症诊断，研究和治疗的试剂盒，组合物和方法，包括但不限于癌症标志物。特别地，本发明涉及复发性基因融合（例如，涉及TYK2的复发性易位）作为诊断标志物和皮肤CD30阳性淋巴增生性疾病（例如淋巴瘤性papulosis;原发性皮肤间变性大细胞淋巴瘤）的临床靶标。

2.

发明申请
METHODS AND BIOMARKERS FOR DETECTION AND TREATMENT OF MATURE T-CELL LEUKEMIA 审中-公开
标题翻译：用于检测和治疗成熟T细胞淋巴细胞的方法和生物标志物

公开(公告)号：WO2015023866A1

公开(公告)日：2015-02-19

申请号：PCT/US2014/051099

申请日：2014-08-14

申请人： THE REGENTS OF THE UNIVERSITY OF MICHIGAN

发明人： ELENITOBA-JOHNSON, Kojo , KIEL, Mark J. , VELUSAMY, Thirunavukkarasu , SAHASRABUDDHE, Anagh , ROLLAND, Delphine , LIM, Megan

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6886 , C12Q2600/118 , C12Q2600/156 , G01N33/57426 , G01N2333/91205 , G01N2800/52

摘要： The present invention relates to methods and biomarkers for detection and characterization of mature T-cell neoplasias / leukemias (e.g., T-cell prolymphocytic leukemia, Sezary syndrome) in biological samples (e.g., tissue samples, blood samples, plasma samples, cell samples, serum samples).

摘要翻译： 本发明涉及用于生物样品（例如，组织样品，血液样品，血浆样品，细胞样品，血液样品，血液样品，血液样品，血清样品）。