公开(公告)号：WO1990014587A1

公开(公告)日：1990-11-29

申请号：PCT/US1990002969

申请日：1990-05-25

Applicant: UNIVERSITY OF UTAH

Inventor： UNIVERSITY OF UTAH ,  McCLENNEN, William, H. ,  ARNOLD, Neil, S. ,  MEUZELAAR, Henk, L., C.

IPC: G01N01/14

CPC classification number: H01J49/0404 ,  G01N1/14 ,  G01N1/2247 ,  G01N1/24 ,  G01N30/10 ,  G01N30/16 ,  G01N2001/225 ,  G01N2030/383

Abstract: The system operates by inducing a sample to flow into an outer chamber (22) and excluding the sample from an inner chamber (18) having an inner chamber orifice (11) located within the outer chamber by inducing a first pressure zone in the inner chamber such that a substantially discrete interface between the first pressure zone and sample is formed at the inner chamber orifice; reducing the first pressure zone to induce the sample to flow through the inner chamber orifice into and through the inner chamber such that the first pressure zone-sample interface is substantially undisturbed when the first pressure zone-sample interface (30) moves therethrough; inducing the sample to flow from the inner chamber into an inner tube (10) having an inner tube orifice within the inner chamber which forms a pathway (12) to a detector (13); inducing a second pressure zone in the inner chamber such that a second substantially discrete interface (31) is formed.

Abstract translation: 该系统通过诱导样品流入外室（22）并且从具有位于外室内部的内室孔口（11）的内室（18）排出样品，通过在内室中引入第一压力区 使得第一压力区和样品之间的基本上离散的界面形成在内室孔口处; 减少第一压力区域以引起样品通过内室孔流入并通过内室，使得当第一压力区 - 样品界面（30）通过其移动时，第一压力区 - 样品界面基本上不受干扰; 使所述样品从所述内室流入内管（10），所述内管（10）在所述内室内具有形成到所述检测器（13）的通路（12）的内管孔。 在内腔中引入第二压力区，从而形成第二基本离散的界面（31）。