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公开(公告)号：WO2019149889A1
公开(公告)日：2019-08-08
申请号：PCT/EP2019/052502
申请日：2019-02-01
IPC分类号： C01B25/32
CPC分类号： A61K8/0275 , A61K8/24 , A61K2800/412 , A61K2800/413 , A61Q11/00 , C01B25/32 , C01B25/327
摘要： Die vorliegende Erfindung betrifft partikulären Hydroxylapatit mit einer spezifischen Partikelfläche und die Herstellung davon. Zudem betrifft die vorliegende Erfindung eine Oralpflegezusammensetzung, welche den erfindungsgemäßen Hydroxylapatit umfasst und die Verwendung des erfindungsgemäßen Hydroxylapatits insbesondere in der Kariesprophylaxe und Remineralisation des Zahnschmelzes.
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公开(公告)号：WO2019133828A1
公开(公告)日：2019-07-04
申请号：PCT/US2018/067887
申请日：2018-12-28
申请人： PAPAZIAN, Mihran , BECKER, David
发明人： PAPAZIAN, Mihran , BECKER, David
CPC分类号： A61Q11/00 , A61K8/11 , A61K8/19 , A61K8/733 , A61K2800/87
摘要： A spherificated dental medicament that includes an outer membrane containing calcium alginate and an internal core containing at least one of a mouth rinse, a mouthwash, a dental paste, and a dental gel, A method of making the spherificated dental medicament includes immersing a dental medicament composition into a solution containing either a soluble alginate or calcium salt, the dental medicament composition comprising a calcium salt or a soluble alginate and at least one of a mouth rinse, a mouthwash, a dental paste and a dental gel, and then removing the dental medicament composition from the solution following formation of a membrane around the dental medicament composition.
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公开(公告)号：WO2019120467A1
公开(公告)日：2019-06-27
申请号：PCT/EP2017/083245
申请日：2017-12-18
CPC分类号： A61Q11/00 , A61K8/25 , C01P2006/19
摘要： Oral care compositions and methods for reducing dental sensitivity or at least partially occluding dentin tubules of teeth in a subject are described herein. The oral care compositions may include an orally acceptable vehicle and a silica blocking agent configured to at least partially occlude dentin tubules of teeth. The silica blocking agents may include silica particles having a particle size distribution (D95) less than or equal to 7 μm and a BET surface area of greater than or equal to 150 m 2 /g.
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公开(公告)号：WO2019118441A1
公开(公告)日：2019-06-20
申请号：PCT/US2018/064920
申请日：2018-12-11
CPC分类号： A61K8/21 , A61K8/25 , A61K8/27 , A61K8/365 , A61K2800/28 , A61K2800/412 , A61K2800/5922 , A61Q11/00 , C09K3/1409
摘要： This invention relates to dentifrice compositions comprising stannous fluoride and a silica abrasive having a N 2 BET surface area of less than 50 m 2 /g and an Einlehner hardness of from 4 to 11, as well as to methods of using these compositions.
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公开(公告)号：WO2019108218A1
公开(公告)日：2019-06-06
申请号：PCT/US2017/064147
申请日：2017-12-01
发明人： PATEL, Neeta , SZEWCZYK, Gregory , MORGAN, Andre , MUIR, Melissa
摘要： Disclosed herein are oral care compositions comprising a zinc amino acid halide complex, and a humectant system comprising polyethylene glycol and propylene glycol as structuring humectants, which compositions have improved rheological stability. Methods of making and using the compositions are also provided.
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公开(公告)号：WO2019107338A1
公开(公告)日：2019-06-06
申请号：PCT/JP2018/043517
申请日：2018-11-27
申请人： ライオン株式会社
IPC分类号： A61K8/81 , A61K8/34 , A61K8/35 , A61K8/42 , A61K8/9789 , A61K8/9794 , A61Q11/00
CPC分类号： A61K8/34 , A61K8/35 , A61K8/42 , A61K8/81 , A61K8/9789 , A61K8/9794 , A61Q11/00
摘要： 温感剤、冷感剤等の感覚刺激成分による口腔刺激が抑制され、かつ香味発現性が良い口腔用組成物を提供する。 （Ａ）重量平均分子量が１，０００以上２０，０００以下のポリアクリル酸塩、及び（Ｂ）サンショウ抽出物、トウガラシ抽出物、ジンジャー抽出物、オランダセンニチ抽出物、サンショオール、カプサイシン、ジンゲロール、ショウガオール、ジンゲロン、スピラントール及びメントール誘導体から選ばれる１種以上を含有する口腔用組成物。更に、（Ｃ）ノニオン性界面活性剤を含有する上記口腔用組成物。
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公开(公告)号：WO2019098787A1
公开(公告)日：2019-05-23
申请号：PCT/KR2018/014193
申请日：2018-11-19
申请人： 한국화학연구원
IPC分类号： A61K31/704 , A23L33/10 , A23L33/125 , A61K8/60 , A61Q11/00
CPC分类号： A23L33/10 , A23L33/125 , A23V2002/00 , A23V2200/30 , A61K8/602 , A61K31/704 , A61Q11/00 , Y02A50/385 , Y02A50/387 , Y02A50/389 , Y02A50/391
摘要： 본 발명은 진세노사이드 유도체 또는 이의 약학적으로 허용가능한 염을 유효성분으로 함유하는 바이러스 감염 저해제에 관한 것으로써, 본 발명에 따른 진세노사이드 유도체 또는 이의 약학적으로 허용가능한 염은 세포 내 아르보바이러스 유전체를 저해하고 아르보바이러스 단백질을 감소시킬 뿐만 아니라, 아르보바이러스에 의한 세포 사멸 보호 효과를 나타내므로 아르보바이러스의 감염을 예방, 개선 또는 치료하는데 유용하게 사용할 수 있다.
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公开(公告)号：WO2019094568A1
公开(公告)日：2019-05-16
申请号：PCT/US2018/059791
申请日：2018-11-08
申请人： ISP INVESTMENTS LLC
CPC分类号： A61Q11/00 , A61K8/24 , A61K8/731 , A61K2800/48 , A61K2800/594
摘要： A substantially anhydrous thickener system in the form of a gel for use in oral care compositions comprising: carboxymethyl cellulose or its salts thereof, a chelating agent, and hydroxyethyl cellulose, in a solvent system, wherein the thickener system is heated to a temperature ranging from about 70°C to about 120°C to form the gel. A method of preparing the thickener system for use in oral care compositions comprises the steps of: a) charging a mixture of hydroxyethyl cellulose and carboxymethyl cellulose into a reaction container, b) dissolving the mixture of a) in a solvent system, c) charging a chelating agent into b), and d) heating the resultant of c) to a temperature of 70° -120° C for at least about 10 minutes.
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公开(公告)号：WO2019094196A1
公开(公告)日：2019-05-16
申请号：PCT/US2018/057345
申请日：2018-10-24
申请人： MERRELL, Scott, P.
发明人： MERRELL, Scott, P.
IPC分类号： A61K8/18 , A61Q11/00 , A23L33/00 , A23L33/125 , A23L33/16
CPC分类号： A61K8/18 , A23L33/125 , A23L33/16 , A23L33/30 , A23L33/40 , A23V2002/00 , A61K2800/30 , A61Q11/00
摘要： The present invention relates to a method for preventing or treating disease in a mammal, particularly a human, by maintaining a fluoride free diet. Such diseases include autism, cancer, Alzheimer's disease, multiple sclerosis, calcification of the pineal gland, diabetes, depression, schizophrenia, psychotic diseases, muscular dystrophy, and others.
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公开(公告)号：WO2019060273A1
公开(公告)日：2019-03-28
申请号：PCT/US2018/051436
申请日：2018-09-18
CPC分类号： A61K8/0225 , A61K8/19 , A61K8/365 , A61K8/416 , A61K8/4926 , A61K8/73 , A61K2800/222 , A61K2800/92 , A61Q11/00
摘要： The present invention relates to a dry mouthwash comprising granules that reconstitute in an aqueous solution, such as water, to produce a solution that tastes and functions as a typical liquid mouthwash.
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