公开(公告)号：WO2006124100A3

公开(公告)日：2009-04-09

申请号：PCT/US2006008389

申请日：2006-03-09

Applicant: ANALIZA INC ,  BELGOVSKIY ALEXANDER ,  CHAIT ARNON

Inventor： BELGOVSKIY ALEXANDER ,  CHAIT ARNON

IPC: H01J49/36

CPC classification number: G01N30/86 ,  G01N30/72 ,  G01N30/8658 ,  H01J49/0009

Abstract: The present invention provides for systems and methods for automated quantification of individual compounds in a mixture. The invention is generally concerned with quantitative analysis of solid, liquid, or gas samples and relies on a separation instrument and on a mass detector. The separation instrument provide means to separate the individual compounds typically according to certain physicochemical property, and the mass detector provides means to determine the amount or concentration of an arbitrary compound using an instrument-specific calibration curve. The present invention provides automated capability to analyze such mixtures without user intervention by varying pre-determined control parameters on one or more of the instruments so as to achieve a high degree of analytical resolution of some or all of the individual compounds in the mixture.

Abstract translation: 本发明提供了用于自动定量混合物中各化合物的系统和方法。 本发明通常涉及固体，液体或气体样品的定量分析，并且依赖于分离仪器和质量检测器。 分离仪器提供通常根据某些物理化学性质分离各种化合物的方法，质量检测器提供使用仪器专用校准曲线确定任意化合物的量或浓度的方法。 本发明提供了通过在一个或多个仪器上改变预定控制参数来分析这些混合物而无需用户干预的自动化能力，从而达到混合物中部分或全部个别化合物的高度分析分辨率。