公开(公告)号：WO2022007825A1

公开(公告)日：2022-01-13

申请号：PCT/CN2021/104908

申请日：2021-07-07

申请人： NOVOZYMES A/S ,  CAO, Yi

发明人： VIDAL, Bernardo, Jr. ,  FERRER, Oscar, Pastor ,  MANNING, Brian ,  SHOUP, Madelyn, Mallison ,  KAASGAARD, Svend, Gunnar ,  STRINGER, Mary, Ann ,  PALMÉN, Lorena, Gonzalez

IPC分类号： C08B30/04 ,  C12P19/00 ,  C12M1/00

摘要： A method for increasing starch yield and/or gluten yield from corn kernels in a wet milling process, comprising contacting a fiber rich fraction of ground kernels, with an effective amount of SO2, and an effective amount of one or more hydrolytic enzymes, wherein at least one of said hydrolytic enzymes is selected from xylanase and/or cellulase enzymes, during a fiber-washing step.

公开(公告)号：WO2022006378A1

公开(公告)日：2022-01-06

申请号：PCT/US2021/040056

申请日：2021-07-01

申请人： NOVOZYMES A/S ,  GIBBONS, Thomas Patrick

发明人： GIBBONS, Thomas Patrick

IPC分类号： C12P7/64 ,  C11B1/02 ,  C11B1/025 ,  C12P7/6445

摘要： The present invention provides a method for improving oil yield from germ in a wet milling process, the method comprising admixing a process stream comprising corn germ with an enzyme composition comprising an effective amount of one or more hydrolytic enzymes, wherein at least one of said hydrolytic enzymes is a xylanase polypeptide selected from the group consisting of: GH5, GH10, GH30, GH11 polypeptides.

公开(公告)号：WO2021202479A1

公开(公告)日：2021-10-07

申请号：PCT/US2021/024816

申请日：2021-03-30

申请人： NOVOZYMES A/S ,  PHAM, Jonathan

发明人： CAI, Xianpeng ,  MULLIKIN, Ronald ,  CORNELISSEN, Sjef ,  HERMANSEN, Casper Kanstrup ,  BREÜNER, Anne Gay ,  HANSEN, Kim ,  DIANO, Audrey ,  MCBRAYER, Brett ,  BROWN, Stephen ,  CHANDLER, Tyler ,  GE, Haiyan ,  RIISGAARD, Frederik Kier ,  CASSELLS, Benny ,  KRISTENSEN, Kirstine Jessen ,  SEREDA, Valentin

IPC分类号： C12P21/02 ,  C12P39/00 ,  C12Y302/01 ,  C12Y302/01008 ,  C12Y302/01014 ,  C12Y302/01017

摘要： The present invention provides submerged fermentation processes of producing one or more polypeptide of interest, the process comprising: a) fermenting one or more microorganism that produces the one more polypeptide of interest in a fermentation broth, and b) adding at least one enzyme to the fermentation broth; OR co-expressing the at least one enzyme in the one or more microorganism and secreting the at least one enzyme into the fermentation broth in an amount sufficient to reduce the viscosity of the fermentation broth, compared to when the at least one enzyme is not added or co-expressed; and, optionally, c) recovering the one or more polypeptide of interest.

公开(公告)号：WO2021180539A1

公开(公告)日：2021-09-16

申请号：PCT/EP2021/055314

申请日：2021-03-03

申请人： DSM IP ASSETS B.V. ,  NOVOZYMES A/S

发明人： CHATELLE, Claire, Véronique ,  LEHMANN, Otto, Martin

IPC分类号： C12Q1/37

摘要： The present invention provides a method and a kit for measuring protease activity in a feed sample. The method and the kit avoids the influence of feed inhibitors present in a feed sample and thus provides a stable and accurate method for measuring protease activity in the feed sample with high sensitivity.

公开(公告)号：WO2021156342A1

公开(公告)日：2021-08-12

申请号：PCT/EP2021/052618

申请日：2021-02-04

申请人： NOVOZYMES A/S

发明人： NIELSEN, Niels-Viktor ,  SIMONSEN, Ole ,  ANDERSEN, Birgitte

IPC分类号： C12N9/02 ,  A61K9/50 ,  C12N9/96 ,  C12N9/98

摘要： The invention provides an enzyme granule comprising a mixture of a laccase and a buffer in an amount capable of maintaining an alkaline pH.

公开(公告)号：WO2021148364A1

公开(公告)日：2021-07-29

申请号：PCT/EP2021/050978

申请日：2021-01-19

申请人： NOVOZYMES A/S

发明人： DAMAGER, Iben ,  MIKKELSEN, Lise, Munch ,  LUND, Henrik

IPC分类号： C11D3/386 ,  C12N9/2405 ,  C12Y301/01003 ,  C12Y301/21 ,  C12Y302/01001 ,  C12Y302/01004 ,  C12Y302/01006 ,  C12Y302/01078 ,  C12Y304/00

摘要： The present invention relates to compositions such as cleaning compositions comprising a mix of enzymes. The invention further relates to use of compositions comprising such enzymes in cleaning processes.

公开(公告)号：WO2021148278A1

公开(公告)日：2021-07-29

申请号：PCT/EP2021/050464

申请日：2021-01-12

申请人： NOVOZYMES A/S

发明人： MUZZI-ERICHSEN, Gloria

IPC分类号： A01H15/00 ,  C07K14/37 ,  C12N1/14 ,  C12N15/80 ,  C12N2310/20 ,  C12N9/14 ,  C12P21/02 ,  C12R2001/885 ,  C12Y306/05002

摘要： The present invention relates to a mutant of a parent filamentous fungal cell, comprising: a polynucleotide encoding a polypeptide of interest; a racA gene encoding a Rho-GTPase RacA protein, wherein the racA gene is modified rendering the mutant partially or completely deficient in the production of the Rho-GTPase RacA protein; and a ras2 gene encoding a GTPase Ras2 protein, wherein the GTPase Ras2 protein is modified to produce a GTPase Ras2 variant comprising a substitution at a position corresponding to position 16 of SEQ ID NO: 11, wherein the combination of the modified racA gene and the Ras2 variant synergistically increases the productivity of the mutant in the production of the polypeptide of interest. The present invention also relates to a method of producing a polypeptide of interest with such a mutant.

公开(公告)号：WO2021126966A1

公开(公告)日：2021-06-24

申请号：PCT/US2020/065293

申请日：2020-12-16

申请人： NOVOZYMES A/S ,  SOONG, Chee-Leong

发明人： KURAKATA, Yuma ,  OHMAN, Brian Frederick

IPC分类号： C12P7/06 ,  C12P19/00 ,  C12Y302/01008

摘要： The present invention relates to processes for producing fermentation products from starch-containing material, wherein a thermostable xylanase that is resistance to inhibition by metal ions in the liquefying starch-containing material is present and/or added during liquefaction.

公开(公告)号：WO2021089750A1

公开(公告)日：2021-05-14

申请号：PCT/EP2020/081228

申请日：2020-11-06

申请人： NOVOZYMES A/S

发明人： NIELSEN, Lone, Kierstein

IPC分类号： C12N9/24 ,  C12N9/96

摘要： The invention provides liquid enzyme compositions which are physically and microbially stable. The compositions are used, for example, in beer brewing processes.

公开(公告)号：WO2021055395A1

公开(公告)日：2021-03-25

申请号：PCT/US2020/050958

申请日：2020-09-16

申请人： NOVOZYMES A/S ,  LIU, Jiyin

发明人： HUANG, Hong Zhi ,  XU, Hui ,  VLASENKO, Elena ,  MCBRAYER, Brett ,  LIU, Ye ,  TANG, Lan ,  HUFFMAN, James Ron ,  SPODSBERG, Nikolaj

IPC分类号： C12N9/24

摘要： The present invention relates to isolated polypeptides having beta-glucanase activity, catalytic domains, carbohydrate binding modules and polynucleotides encoding the polypeptides, catalytic domains or carbohydrate binding modules. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains or carbohydrate binding modules. The present invention further relates to processes for producing fermentation products from starch-containing or cellulosic-containing material, as well as an enzyme blend or composition, or a recombinant host cell or fermenting organism suitable for use in processes of the invention.