公开(公告)号：WO2023015969A1

公开(公告)日：2023-02-16

申请号：PCT/CN2022/090856

申请日：2022-05-05

申请人： 浙江大学

发明人： 梁波 ,  李天瑜 ,  叶志超 ,  叶学松

IPC分类号： A61B5/0205 ,  A61B5/268 ,  A61B5/28 ,  G01N27/327

摘要： 一种同步监测生理生化参数的导电水凝胶纸基设备。利用多孔的PEDOT:PSS水凝胶在纸纤维上实现自组装，从而使其具有良好的导电性和良好的水润湿性，以实现高效的电子传输和物质扩散，保证其能够作为一个低阻抗的心电传感器和高灵敏的电化学传感器。同时，自发的毛细管流动效应使该滤纸可以作为纸质微流体的亲水通道，用于捕获和分析汗液。运动测试时，水凝胶纸贴片贴于皮肤表面采集心电数据和汗液中的目标物质浓度，从而实现无创监测。可以实现一个柔性的、低成本的、多功能的纸质分析装置，用于运动过程中生理和生化信号的同步监测。

公开(公告)号：WO2022204554A1

公开(公告)日：2022-09-29

申请号：PCT/US2022/022014

申请日：2022-03-25

申请人： UMANA MEDICAL TECHNOLOGIES LTD. ,  MARY FRANCES LUDWIG

发明人： ATTARD TREVISAN, Adrian ,  ZERAFA, Antoine ,  SULTANA, Brendon ,  CAUCHI, Christopher ,  CAUCHI, Eman ,  GALLOPPINI, Alessandro ,  CAMILLERI, Andrea

IPC分类号： A61B5/257 ,  A61B5/268 ,  A61B5/274 ,  A61B5/00

摘要： A multifunctional electrophysiological monitoring system includes a body-worn tattoo sensor pattern (102) and an electrophysiological monitor (200) connected to sensor contacts (150) of the pattern. A dongle (600) performs a supplemental function, such as acquiring information about a physiological parameter. The dongle interfaces with a port (206) of the monitor. The monitor interfaces wirelessly with a mobile communication device (300) and a monitor network. In an embodiment, the monitor transmits ECG, EMG, or EEG signals. The dongle may provide further monitoring such as body temperature or blood oxygen saturation level. In some embodiments a plurality of dongles may be connected to the monitor.

公开(公告)号：WO2022056465A1

公开(公告)日：2022-03-17

申请号：PCT/US2021/050273

申请日：2021-09-14

申请人： BLACKROCK MICROSYSTEMS, LLC ,  TECHNICAL UNIVERSITY OF MUNICH ,  JACOB, Simon Nikolas ,  GEMPT, Jens

发明人： WIEBE, Sherman Perry ,  LEBER, Moritz Michael

IPC分类号： A61B5/383 ,  A61B5/00 ,  A61B5/268

摘要： Embodiments disclosed include systems and methods to stimulate and record electrical activity from a medium (e.g., neural tissue) with high precision, accuracy, and fidelity. The disclosed systems include an electrode array attached to a carrier facilitating the insertion of the array into biological tissue for mapping and characterization of tissue. Embodiments can be used for acute and/or chronic applications for recording activity, stimulating activity, and/or measuring impedance via spectroscopy. Embodiments can be used to characterize tissue near, surrounding, and/or outside of a brain tumor using a thin film electrode array. Embodiments can be used to characterize and/or manipulate (i) tumor cells, (ii) peri-tumor tissue, and/or (iii) non-tumor tissue, using electrophysiological recordings, impedance spectroscopy, and/or stimulation. Embodiments can help better define an extent of tissue to excise, characterize the tumor cells, and/or study tumor-nontumor signaling. Embodiments can guide surgical procedures, and improve effectiveness of rehabilitation, therapy, and/or tumor suppression.