公开(公告)号：WO02039901A1

公开(公告)日：2002-05-23

申请号：PCT/JP2001/009987

申请日：2001-11-15

IPC: A61B8/00 ,  G01S15/89

CPC classification number: A61B8/4281 ,  A61B8/4209 ,  A61B8/481 ,  A61B8/483 ,  G01S7/52039 ,  G01S7/52085 ,  G01S7/52095 ,  G01S15/8918 ,  G01S15/8925 ,  G01S15/8945 ,  G01S15/8993 ,  Y10S128/916

Abstract: A ultrasonic diagnostic device for forming a 3-D echo data capturing area. A beam address array is comprised of a plurality of ultrasonic beam addresses constituting a 3-D echo data capturing space. The beam address array is divided into a plurality of address groups, for each of which two address scans are executed repeatedly. Accordingly, a time interval between two pieces of data is shortened, when differential operation is performed on two pieces of data acquired in the same beam position. The presence or behavior of ultrasonic contrast media in a biological tissue is displayed as a 3-D differential image.

Abstract translation: 一种用于形成3-D回波数据捕获区域的超声波诊断装置。 波束地址阵列由构成3-D回波数据捕获空间的多个超声束地址构成。 波束地址阵列被分成多个地址组，对于其中重复执行两个地址扫描的每个地址组。 因此，在对同一波束位置获取的两条数据执行差分运算时，两条数据之间的时间间隔被缩短。 生物组织中超声波造影剂的存在或行为显示为3-D差分图像。

公开(公告)号：WO00066000A1

公开(公告)日：2000-11-09

申请号：PCT/EP2000/003536

申请日：2000-04-17

IPC: A61B8/14 ,  A61B8/00 ,  A61B8/06 ,  G01S7/52 ,  G01S15/89

CPC classification number: A61B8/481 ,  A61B8/543 ,  G01S7/52038 ,  G01S7/52039 ,  G01S15/8981

Abstract: Perfusion of tissue such as the myocardium by a microbubble contrast agent is imaged in realtime by a multiple pulse technique which uses low power transmit pulses which are sufficient to elicit a harmonic response from the microbubbles but are not high enough in power to cause substantial destruction to the microbubbles. In a preferred embodiment the realtime microbubble image sequence is displayed in color, overlaid with a grayscale image of the surrounding tissue in the region being imaged.

Abstract translation: 通过微泡造影剂对诸如心肌的组织灌注通过多脉冲技术实时成像，所述多脉冲技术使用足以引起来自微泡的谐波响应的低功率发射脉冲，但是不足以引起大量破坏 微泡。 在优选实施例中，实时微泡图像序列以彩色显示，并与被成像区域中的周围组织的灰度图像重叠。

公开(公告)号：WO1996009002A1

公开(公告)日：1996-03-28

申请号：PCT/IB1995000773

申请日：1995-09-21

Applicant: BRACCO RESEARCH S.A.

Inventor： BRACCO RESEARCH S.A. ,  ARDITI, Marcel

IPC: A61B08/00

CPC classification number: A61B8/481 ,  G01S7/52038 ,  G01S7/52039

Abstract: This invention is applicable to the electronic circuits found in echographic imaging instruments, such as those used for medical diagnosis. Its implementation requires the injection of specific contrast agents in the body, or more generally in the region to be imaged. The underlying principle of the new imaging proposed is based on use of frequency dependent behaviour of the ultrasound contrast agents containing microbubbles. In essence, these imaging principles exploit certain physical "signatures" of the contrast agent responses, allowing increased contrast with respect to tissue background. This contrast enhancement is much larger than what is determined from direct echo amplitude monitoring.

Abstract translation: 本发明可应用于回波成象仪器中发现的电子电路，例如用于医疗诊断的那些。 其实施需要在体内或更一般地在待成像的区域中注射特定的造影剂。 提出的新成像的基本原理是基于使用含有微泡的超声造影剂的频率依赖性行为。 实质上，这些成像原理利用了造影剂反应的某些物理“签名”，允许增加对组织背景的对比度。 这种对比度增强远远大于直接回波幅度监测所确定的。