公开(公告)号：WO1997032896A1

公开(公告)日：1997-09-12

申请号：PCT/JP1997000728

申请日：1997-03-07

Applicant: YUKIGUNI MAITAKE CO., LTD.

Inventor： YUKIGUNI MAITAKE CO., LTD. ,  NANBA, Hiroaki ,  KUBO, Keiko

IPC: C07K14/375

CPC classification number: A61K36/07 ,  C07K14/375

Abstract: An antitumor substance obtained from the mycelia or fruit bodies of hen-of-the-woods (grifola frondosa) by extraction and fractionation and having a potent immunopotentiating activity. The antitumor activity and immunopotentiating power can be enhanced by extracting the mycelia or fruit bodies with hot water and adding alcohol to the extract in a final concentration of 20-70 % by volume (low-concentration addition) to remove the suspension or deposits.

Abstract translation: 通过提取和分级从丝状体或藤本植物（grifola frondosa）获得的抗肿瘤物质，并具有有效的免疫增强活性。 通过用热水提取菌丝体或果实体并以最终浓度为20-70体积％（低浓度添加）向提取物中加入酒精以除去悬浮液或沉积物，可以增强抗肿瘤活性和免疫增强能力。