Abstract:
The present disclosure is directed to pre-filled injection devices and related therapeutic formulations and methods that lack fatty acid particles. The therapeutic formulation may remain fatty acid particle free or substantially fatty acid particle free over time or when subjected to accelerated aging conditions.
Abstract:
Delivering ultrasonic energy to a target musculoskeletal tissue site includes connecting a delivery device to a vacuum source, a fluid source, and a power signal source. The delivery device has a housing portion maintaining an ultrasound transducer and a tip portion having a sleeve and a cannula. The cannula is coupled to the ultrasound transducer and received in the sleeve to define a covered portion and an exposed portion. Ultrasonic energy is generated by sending a power signal from the power signal source to the ultrasound transducer. The ultrasonic energy is transmitted from the ultrasound transducer to the cannula, such that the exposed portion of the cannula delivers ultrasonic energy at a frequency that is pre-selected to debride musculoskeletal tissue upon percutaneous insertion of the tip portion.
Abstract:
The implant (20) is shaped to generally mimic the form of the trapezium (12), or portions thereof. For example, the implant optionally defines a first metacarpal projection (32) and a second metacarpal projection (34) spaced from the first metacarpal projection to form a C-type, or cuff-type receptacle (36) for receiving the first metacarpal (15) such as the first and second metacarpal projections extend along either side of the first metacarpal. The receptacle optionally acts as a support surface (36A) for the first metacarpal during articulation thereof. In some embodiments, the first metacarpal projection is configured to extend adjacent the end portion of the first metacarpal that is adjacent the CMC joint (10) and the second metacarpal projection is configured to extend into the space (19) between the end portions of the first and second metacarpals (15, 18), thereby helping maintain the intermetacarpal spacing between the first and second metacarpals. The implant may comprise an inflatable cover for minimally invasive implantation.
Abstract:
Methods of correcting a spinal deformity, including securing a first rod on a first side of a spine, securing an anchor on a second side of a spine, securing a lateral coupling between the rod and the anchor, translating and derotating the spine to correct the spinal deformity by adjusting an effective length of the lateral coupling, and securing a second rod on a second side of the spine to provide secondary stabilization to the spine.
Abstract:
A spinal management system includes a stabilizing member (12) adapted to extend substantially longitudinally along a target region of a spine tending to exhibit a defective curvature and a set of stabilizing anchors (14A, 14B) adapted for fixation to vertebrae and to receive the stabilizing member to secure the stabilizing member against substantial transverse translation relative to the vertebrae. The system also includes a first correction anchor (18B) adapted for fixation to a vertebra, a second correction anchor (18A) adapted for fixation to a vertebra, and a connection (22C) between the stabilizing member and the first correction anchor and between the first and second correction anchors adapted such that when the connection is tensioned a compressive force is selectively exerted between the first and second correction anchors.
Abstract:
The present disclosure is directed to pre-filled multi-dose injection devices and related therapeutic formulations and methods that lack a cloud point. The therapeutic formulation may be a transparent solution, and preservatives may remain within the aqueous phase without being phase separated to retain antimicrobial effectiveness.
Abstract:
Systems and methods for controlling a rotational effect on stabilizing vertebrae during and/or after deformity correction by directing reactive forces toward, on opposite sides of, and/or relatively closer to the transverse centers of rotation of the stabilizing vertebrae. The system (10) comprises a stabilizing member (12) adapted to extend between the first stabilizing vertebra and the second stabilizing vertebra, a first stabilizing anchor (14A) adapted to locate the stabilizing member with respect to the first stabilizing vertebra, a second stabilizing anchor (14B) adapted to locate the stabilizing member with respect to the second stabilizing vertebra, a correction anchor (18A) adapted to be secured to the correction vertebra and a connector (22A) secured between the stabilizing member and the correction anchor.
Abstract:
Systems, devices, and associated methods for correcting and stabilizing spinal column deformities that promote ease of use and surgical technique, help minimize attachment anchor sites, facilitate use of straight or contoured rods, and/or help promote a more natural, physiologic motion of the spinal column during and/or after correction.