Abstract:
The present invention provides a bispecific epitope binding protein comprising an anti-4-1BB agonist antibody and a PD-1 protein or a fragment thereof that binds to PD-L1 with high affinity. The bispecific epitope binding protein simultaneously and independently binds to 4-1BB and PD-L1, which engage 4-1BB upregulated T cells, especially effector CDS + T cells, with tumor cells expressing PD-L1. These interactions induce strong activation of the cytotoxic activity of anti-tumor effector CD8+ T cells by both blocking PD-1/PD-L1-mediated inhibitory signaling and activating 4-1BB-mediated costimulatory signaling in mouse models. This bispecific epitope binding protein has a much stronger oncolytic effect compared to each component alone.
Abstract:
The present invention provides a method and apparatus for allocating uplink resources in a wireless communication system. A base station transmits uplink resource allocation information to a terminal in order to allocate a plurality of clusters that are dispersed in a frequency domain to uplink resources, and receive data on the plurality of clusters. The plurality of clusters is allocated on the basis of at least one of the following: location of each cluster in the frequency domain and gap between the plurality of clusters.
Abstract:
The present invention relates to a wireless communication system, and more particularly to a transmission method and apparatus using a codebook in a wireless communication system supporting multiple antennas. According to one embodiment of the present invention, a method for transmitting, by a base station, a downlink signal using a plurality of transmission antennas comprises the steps of: receiving a PMI from a terminal; applying a precoding matrix indicated by the PMI in a codebook to a plurality of layers, and performing a precoding; and transmitting the precoded signal to the terminal through a plurality of transmission antennas. Among precoding matrices included in the codebook, a precoding matrix for transmission layers which are even in number can be constructed as a 2x2 matrix which contains matrices (W1) as four elements, the matrix (W1) having the number of rows equal to the number of transmission antennas and the number of columns equal to half the number of transmission antennas, wherein the first and second columns of the first row in the 2x2 matrix may be multiplied by a coefficient of 1, the first column of the second row may be multiplied by coefficient "a" of a phase, and the first column of the second row may be multiplied by "-a".
Abstract:
The present invention relates to a wireless communication system. More particularly, the present invention relates to a method and apparatus for transmitting a plurality of PUCCHs in a wireless communication system, wherein the method comprises the following steps: checking a resource for a first PUCCH among the plurality of PUCCHs; inferring, from the resource for the first PUCCH, a resource for the remaining one or more second PUCCHs excluding the first PUCCH among the plurality of PUCCHs; and transmitting the plurality of PUCCHs simultaneously via corresponding relevant resources.
Abstract:
Disclosed are a method and device for transmitting a reference signal in a wireless communication system. A base station: maps each demodulation reference signal (DMRS) of each of a plurality of layers into a first resource element (RE) set and a second resource element set including four resource elements over four orthogonal frequency division multiplexing (OFDM) symbols within a subframe; allocates first orthogonal cover codes (OCCs) having a length of 4 to each DMRS mapped into said first resource element set; allocates second OCCs having a length of 4 to each DMRS mapped into said second resource element set; and transmits each DMRS mapped into said first resource element set and said second resource element set. Said subframe includes two slots, and each slot includes six OFDM symbols. Said second OCCs are formed by respectively swapping positions of bits that constitute said first OCCs.
Abstract:
Provided are a method and apparatus for allocating a plurality of layers to a plurality of antenna ports in a wireless communication system. The method comprises: mapping the plurality of layers to the respective antenna ports; and mapping demodulation reference signals (DMRS) of the plurality of layers to a first code division multiplexing (CDM) set or to a second CDM set, and transmitting the signals via the plurality of antenna ports.
Abstract:
Disclosed are a terminal device for controlling uplink transmission power and a method therefor. A receiving antenna receives uplink transmission mode change information from a base station. A processor determines a transmission power value to be used for the uplink transmission by means of an offset value corresponding to the uplink transmission mode change information. A transmitting antenna transmits an uplink signal with the determined transmission power value.
Abstract:
A data transmission method and device are provided in a wireless communication system. A user equipment transmits uplink data using a first physical uplink shared channel (PUSCH) resource, allocated to a first component carrier (CC) among a plurality of CC's, in a sounding reference signal (SRS) subframe. The plurality of CC's in said SRS subframe includes a single carrier-frequency division multiple access (SRS SC-FDMA) symbol, which is reserved for transmitting SRS.
Abstract:
The present invention relates to a wireless communication system. More particularly, the present invention relates to a method for transmitting acknowledgement/negative ACK (ACK/NACK) in a wireless communication system which supports carrier aggregation, and to an apparatus for the method, wherein the method comprises the following steps: detecting one or more control channels from a plurality of component carriers; receiving one or more data indicated by the downlink control information loaded onto said one or more control channels; and transmitting ACK/NACK information relating to said one or more data via a physical uplink control channel (PUCCH), wherein each of the pieces of downlink control information includes count information which is set in connection with the entire control channel actually allocated to a terminal.
Abstract:
The present invention relates to a wireless communication system. More particularly, the present invention relates to a method for transmitting a signal via a physical uplink control channel (PUCCH) in a wireless communication system, and to an apparatus for the method, wherein the method is configured such that a terminal transmits a signal via the PUCCH and multiple antennas, and comprises the following steps: obtaining a first modulated symbol sequence from control information; performing a spreading process on modulated symbols corresponding to each of the slots in the PUCCH from among the first modulated symbol sequence, such that the modulated symbols correspond to the respective single carrier frequency division multiplexing (SC-FDMA) symbols in the relevant slots, so as to obtain a plurality of spread second modulated symbol sequences corresponding to the respective SC-FDMA symbols in each slot; and transmitting, in the relevant SC-FDMA symbols in the PUCCH, the plurality of spread second modulated symbol sequences via multiple antennas, wherein resources used in the transmission via the PUCCH are orthogonal to one another between antenna ports.